{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:58:43Z","timestamp":1782845923287,"version":"3.54.5"},"reference-count":33,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Cardio"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Efforts to improve diversity in clinical trials often prioritize recruitment based on broad demographic factors. This approach may overlook the influence of community context and health-related social needs on health behaviors, including sodium intake, a key modifiable risk factor for hypertension and cardiovascular disease.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This study aims to assess the impact of enrollment site, sociodemographic factors, and health-related social needs on baseline dietary sodium intake among participants in a mobile health clinical trial aimed at lowering blood pressure.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The myBPmyLife study is a prospective, randomized controlled trial evaluating a mobile health intervention to lower blood pressure through increased physical activity and lower sodium food choices. Participants with hypertension were recruited from a university health system and a federally qualified health center (FQHC). All participants completed a validated sodium screener at enrollment. Sociodemographic data and health-related social needs were self-reported. Univariable and multivariable linear regression models were used to evaluate the associations between sodium intake and participant characteristics. This analysis presents a cross-sectional examination of the baseline characteristics of participants enrolled in the myBPmyLife study.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Among 600 included participants, 96 (16.0%) were from the FQHC. Mean age was 60.1 (SD 13.5) years; 48.2% (289\/600) were women, and 13.0% (78\/600) were Black. FQHC participants were significantly younger (mean age 47.9, SD 11.1 vs 62.5, SD 12.7 years), more likely to be Black (43\/96, 44.8% vs 35\/504, 6.9%), and 8.5 times more likely to have difficulty paying for their health-related social needs. Mean baseline sodium intake was 3082.3 (SD 1072.5) mg\/day, with 85.5% (513\/600) of participants exceeding the World Health Organization\u2019s recommended daily sodium limit. Baseline sodium intake was significantly higher for FQHC participants (mean difference 381.1, SD 1064.2 mg\/d; 95% CI 84.5-677.7;\n P<\/jats:italic>\n =.01), men (mean difference 543.9, SD 1038.3 mg\/d; 95% CI 377.3-710.5;\n P<\/jats:italic>\n <.001), Black participants (mean difference 442.5, SD 1043.4 mg\/d; 95% CI 119.7-765.3;\n P<\/jats:italic>\n =.008) and those with difficulty affording basic needs (mean difference 338.1, SD 1066.7 mg\/d; 95% CI 95.2-581.0;\n P<\/jats:italic>\n =.02). Sodium intake was lower in older participants (\u2212196.4 mg\/d per 10 years; 95% CI \u2212258.0 to \u2212134.9;\n P<\/jats:italic>\n <.001). In a multivariable analysis, age, gender, and race remained independently associated with sodium intake, while differences by site and health-related social needs were not statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Differences in sodium intake were observed across sociodemographic groups. While the enrollment site was not independently associated with sodium intake after adjustment, it played a role in shaping the participant population, evidenced by the differences in demographics and health-related social needs among participants based on enrollment site. These findings underscore the importance of recruiting from distinct clinical settings to capture a range of contextual factors that influence health behaviors. Clinical trials aiming for representativeness should consider both individual- and community-level factors during recruitment to more accurately inform interventions and health outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/71343","type":"journal-article","created":{"date-parts":[[2025,8,31]],"date-time":"2025-08-31T15:50:07Z","timestamp":1756655407000},"page":"e71343-e71343","source":"Crossref","is-referenced-by-count":0,"title":["Daily Dietary Sodium Intake Among Clinical Trial Participants Recruited From a University Health System or a Federally Qualified Health Center: Secondary Analysis of Baseline Participant Characteristics"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-1425-5674","authenticated-orcid":false,"given":"Gabriella V","family":"Rubick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2910-1879","authenticated-orcid":false,"given":"Michael P","family":"Dorsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0924-3135","authenticated-orcid":false,"given":"Scott L","family":"Hummel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5846-7557","authenticated-orcid":false,"given":"Tanima","family":"Basu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4582-0034","authenticated-orcid":false,"given":"Evan","family":"Luff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2379-6553","authenticated-orcid":false,"given":"Kimberly","family":"Warden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6725-8479","authenticated-orcid":false,"given":"Michael","family":"Giacalone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0149-997X","authenticated-orcid":false,"given":"Sarah","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7186-1383","authenticated-orcid":false,"given":"Mark W","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3088-9838","authenticated-orcid":false,"given":"Lesli E","family":"Skolarus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4331-6649","authenticated-orcid":false,"given":"Brahmajee K","family":"Nallamothu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9538-3926","authenticated-orcid":false,"given":"Jessica R","family":"Golbus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Boden-Albala B Waddy SP Appleton N Kuczynski H Nangle E Recruitment PNS . 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