{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:03:02Z","timestamp":1782846182957,"version":"3.54.5"},"reference-count":26,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Gingival recession and periodontal pockets are the results of the gradual deterioration of the alveolar bone and periodontal ligament caused by periodontitis, which is caused by inflammation of the tissues supporting the tooth. The primary goal of periodontal therapy is to eradicate these aberrant traits. Despite being a popular treatment, scaling and root planing (SRP) has limitations, such as difficulty accessing deeper pockets and root concavities.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The aim of this study is to assess the effectiveness of oxygen-releasing gel as a supplement to nonsurgical treatment for chronic periodontitis.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Twenty-two systemically healthy people with sites of chronic periodontitis were the participants of a split-mouth randomized controlled experiment. For every patient, two locations were chosen and divided into two groups at random. In total, 44 sites were chosen and divided into two groups: Group I (the test group) consisted of 22 test sites, while Group II (the control group) consisted of 22 control sites. While group II underwent SRP alone, group I underwent SRP followed by the use of BlueM oral gel. Plaque index, full mouth bleeding score, clinical attachment level, and probing pocket depth were measured at baseline, one month, and three months, and were compared appropriately.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n All the clinical measurements will be recorded. It can be anticipated that SRP followed by the use of BlueM oral gel will provide additional benefits in the management of chronic periodontitis by promoting better healing and clinical outcomes.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Within the constraints of this study, it can be anticipated that by encouraging improved healing and clinical results in chronic periodontitis, oxygen-releasing gel is more advantageous when used in conjunction with SRP than when SRP is done alone.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/75795","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T16:50:09Z","timestamp":1753375809000},"page":"e75795-e75795","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Evaluation of Effectiveness of Oxygen-Releasing Gel With Scaling and Root Planing (SRP) With That of Scaling and Root Planing Alone in the Management of Chronic Periodontitis Patients: Study Protocol for Cross-Sectional Survey"],"prefix":"10.2196","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3878-4954","authenticated-orcid":false,"given":"Geeta","family":"Bhandari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7093-5221","authenticated-orcid":false,"given":"Priyanka","family":"Jaiswal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9440-8048","authenticated-orcid":false,"given":"Shweta","family":"Bhagat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5726-2637","authenticated-orcid":false,"given":"Sakshi","family":"Kotecha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,3,2]]},"reference":[{"issue":"S1","key":"R1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri\u2010Implant Diseases and Conditions","volume":"89","author":"Papapanou","journal-title":"J Periodontol"},{"issue":"11","key":"R2","doi-asserted-by":"publisher","first-page":"4950","DOI":"10.1128\/JCM.41.11.4950-4954.2003","article-title":"Comparison of real-time PCR and culture for detection of Porphyromonas gingivalis in subgingival plaque samples","volume":"41","author":"Boutaga","journal-title":"J Clin Microbiol"},{"issue":"3","key":"R3","doi-asserted-by":"publisher","first-page":"392","DOI":"10.4103\/0972-124X.100918","article-title":"Evaluation of efficacy of tetracycline fibers in conjunction with scaling and root planing in patients with chronic periodontitis","volume":"16","author":"Sadaf","journal-title":"J Indian Soc Periodontol"},{"issue":"5","key":"R4","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1111\/j.1600-051x.1994.tb00725.x","article-title":"Influence of a single application of subgingival chlorhexidine gel or tetracycline paste on the clinical parameters of adult periodontitis patients","volume":"21","author":"Unsal","journal-title":"J Clin Periodontol"},{"issue":"9","key":"R5","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1177\/0022034519860449","article-title":"The subgingival microbiome relationship to periodontal disease in older women","volume":"98","author":"Genco","journal-title":"J Dent Res"},{"issue":"6","key":"R6","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.sdentj.2024.04.004","article-title":"Topical oxygen therapy as a novel strategy to promote wound healing and control the bacteria in implantology, oral surgery and periodontology: a review","volume":"36","author":"Leventis","journal-title":"Saudi Dent J"},{"issue":"2","key":"R7","doi-asserted-by":"publisher","DOI":"10.3390\/life12020218","article-title":"Pathogenic molecular mechanisms in periodontitis and peri-implantitis: role of advanced glycation end products","volume":"12","author":"Plemmenos","journal-title":"Life (Basel)"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Wang XX Chen Y Leung WK . 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