{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:03:07Z","timestamp":1782846187945,"version":"3.54.5"},"reference-count":38,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Smoking cessation plans under Japan\u2019s national health insurance system are hindered by low completion and success rates. A small-group intervention combining nicotine replacement therapy with digital peer support demonstrated improved smoking cessation success outcomes. However, the extent to which the type of tobacco products used affects the program\u2019s efficacy remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the differences in smoking cessation success rates among cigarette-only smokers, heated tobacco product (HTP)\u2013only users, and individuals who use both (dual smokers), following a group-based intervention combining nicotine replacement therapy and a digital peer\u2013supported app.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective study involved smokers from Japanese workplaces who owned smartphones. Participants received free nicotine replacement therapy (either patches or gum) and access to a digital peer support app. This app facilitated anonymous group chats (up to 5 participants) to encourage interactions and smoking cessation efforts by sharing activity reports, including photos and comments. Participants were classified into 3 groups: cigarette-only smokers, HTP-only users, and dual smokers. Logistic regression analysis was conducted to compare cessation success rates, with cigarette-only smokers being the reference group (odds ratios [ORs] and 95% CIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 435 participants were included in the final analysis, comprising 163 cigarette-only smokers (37.5%), 218 HTP-only users (50.1%), and 54 dual smokers (12.4%). The participants had a mean age of 46.6 (SD 10.1) years, with a predominant male representation (416\/435, 95.6%) and a significant proportion (296\/435, 68.1%) having more than 20 years of smoking history. The smoking cessation success rate was significantly higher among HTP-only users than among cigarette-only smokers (63.3% vs 52.8%; adjusted OR 1.84, 95% CI 1.57\u20102.16). Conversely, dual smokers exhibited a nonsignificantly lower success rate than cigarette-only smokers (48.1% vs 52.8%; adjusted OR 0.96, 95% CI 0.79\u20101.16).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A group-based smoking cessation program using a digital peer support app yielded higher success rates among HTP-only users than among cigarette-only smokers. However, no significant differences were found in dual smokers. These findings highlight the importance of considering tobacco product type in workplace cessation programs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/75876","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T01:24:47Z","timestamp":1754443487000},"page":"e75876-e75876","source":"Crossref","is-referenced-by-count":2,"title":["Smoking Cessation Strategies for Different Types of Cigarette Users Using a Digital Peer\u2013Supported App and Nicotine Aids: Prospective Study"],"prefix":"10.2196","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-8461-4488","authenticated-orcid":false,"given":"Shota","family":"Yoshihara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8083-255X","authenticated-orcid":false,"given":"Kayoko","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8674-3476","authenticated-orcid":false,"given":"Chiaki","family":"Uemura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8848-6329","authenticated-orcid":false,"given":"Shin","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0692-9769","authenticated-orcid":false,"given":"Daichi","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9947-8984","authenticated-orcid":false,"given":"Ying","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6317-3904","authenticated-orcid":false,"given":"Hiroshi","family":"Yamato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2025,8,5]]},"reference":[{"key":"R1","unstructured":"Heated tobacco product: information sheet. World Health Organization. 2020. URL: https:\/\/www.who.int\/publications\/i\/item\/WHO-HEP-HPR-2020.2 [Accessed 11-12-2024]"},{"issue":"6","key":"R2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17062161","article-title":"Use of multiple tobacco and tobacco-like products including heated tobacco and e-cigarettes in Japan: a cross-sectional assessment of the 2017 JASTIS Study","volume":"17","author":"Sugiyama","journal-title":"Int J Environ Res Public Health"},{"key":"R3","unstructured":"Report of the National Health and Nutrition Survey in Japan [Report in Japanese]. Ministry of Health, Labour, and Welfare of Japan; 2023. URL: https:\/\/www.mhlw.go.jp\/content\/10900000\/001338334.pdf [Accessed 20-07-2025]"},{"issue":"2","key":"R4","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17020409","article-title":"Heat not burn tobacco product-a new global trend: impact of heat-not-burn tobacco products on public health, a systematic review","volume":"17","author":"Ratajczak","journal-title":"Int J Environ Res Public Health"},{"issue":"Suppl 1","key":"R5","doi-asserted-by":"publisher","first-page":"s111","DOI":"10.1136\/tobaccocontrol-2018-054340","article-title":"Heated tobacco products: another tobacco industry global strategy to slow progress in tobacco control","volume":"27","author":"Bialous","journal-title":"Tob Control"},{"issue":"26","key":"R6","doi-asserted-by":"publisher","first-page":"22111","DOI":"10.1021\/acsomega.2c01527","article-title":"Should IQOS emissions be considered as smoke and harmful to health? A review of the chemical evidence","volume":"7","author":"Uguna","journal-title":"ACS Omega"},{"issue":"5","key":"R7","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1136\/tobaccocontrol-2018-054419","article-title":"Heat-not-burn tobacco products: a systematic literature review","volume":"28","author":"Simonavicius","journal-title":"Tob Control"},{"issue":"8","key":"R8","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18084079","article-title":"Lung damage caused by heated tobacco products and electronic nicotine delivery systems: a systematic review","volume":"18","author":"Bravo-Guti\u00e9rrez","journal-title":"Int J Environ Res Public Health"},{"key":"R9","unstructured":"Special survey on the effectiveness of smoking cessation treatment under the nicotine dependence management fee: results from the 2017 survey related to the FY2016 revision of medical service fees [Report in Japanese]. Central Social Insurance Medical Council; 2018. URL: https:\/\/www.mhlw.go.jp\/content\/12404000\/000569129.pdf [Accessed 20-07-2025]"},{"issue":"7","key":"R10","doi-asserted-by":"publisher","first-page":"1094","DOI":"10.1093\/ntr\/ntab018","article-title":"Effectiveness of varenicline versus combination nicotine replacement therapy for smoking cessation: one-year outcomes in a smoking cessation clinic in Taiwan","volume":"23","author":"Hsueh","journal-title":"Nicotine Tob Res"},{"issue":"4","key":"R11","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1001\/jama.2015.19284","article-title":"Effects of nicotine patch vs varenicline vs combination nicotine replacement therapy on smoking cessation at 26 weeks: a randomized clinical trial","volume":"315","author":"Baker","journal-title":"JAMA"},{"issue":"2","key":"R12","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1007\/s13142-017-0492-2","article-title":"A systematic review of smartphone applications for smoking cessation","volume":"7","author":"Haskins","journal-title":"Transl Behav Med"},{"issue":"3","key":"R13","doi-asserted-by":"publisher","first-page":"412","DOI":"10.3390\/jpm4030412","article-title":"mHealth for smoking cessation programs: a systematic review","volume":"4","author":"Ghorai","journal-title":"J Pers Med"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.2196\/42776","article-title":"The usefulness of a smartphone app-based smoking cessation program for conventional cigarette users, heated tobacco product users, and dual users: retrospective study","volume":"25","author":"Noda","journal-title":"J Med Internet Res"},{"issue":"12","key":"R15","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-063489","article-title":"Outcomes of a telemedicine smoking cessation programme for heated tobacco product users in Japan: a retrospective cohort study","volume":"12","author":"Nomura","journal-title":"BMJ Open"},{"issue":"9","key":"R16","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1093\/ntr\/ntad059","article-title":"Effectiveness of peer-support interventions for smoking cessation: a systematic review and meta-analysis","volume":"25","author":"Yuan","journal-title":"Nicotine Tob Res"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.2196\/56184","article-title":"Digital peer-supported app intervention to promote physical activity among community-dwelling older adults: nonrandomized controlled trial","volume":"7","author":"Tabira","journal-title":"JMIR Aging"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.2196\/53759","article-title":"Smartphone-based digital peer support for a walking intervention among public officers in Kanagawa Prefecture: single-arm pre- and postintervention evaluation","volume":"8","author":"Okamoto","journal-title":"JMIR Form Res"},{"issue":"8","key":"R19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0305765","article-title":"Impact on step count by commitment-based health application","volume":"19","author":"Takebayashi","journal-title":"PLoS One"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.2196\/72659","article-title":"Effects of using a digital peer-supported app on glycated hemoglobin changes among patients with type 2 diabetes: prospective single-arm pilot study","volume":"9","author":"Yoshihara","journal-title":"JMIR Form Res"},{"issue":"1","key":"R21","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-22337-3","article-title":"Heated tobacco products and circulating high-density lipoprotein cholesterol concentrations","volume":"12","author":"Hu","journal-title":"Sci Rep"},{"issue":"e1","key":"R22","doi-asserted-by":"publisher","first-page":"e50","DOI":"10.1136\/tobaccocontrol-2020-056237","article-title":"Nicotine dependence of cigarette and heated tobacco users in Japan, 2019: a cross-sectional analysis of the JASTIS Study","volume":"31","author":"Lau","journal-title":"Tob Control"},{"issue":"11","key":"R23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0260154","article-title":"Use of heated tobacco products by people with chronic diseases: The 2019 JASTIS study","volume":"16","author":"Nakama","journal-title":"PLoS One"},{"key":"R24","unstructured":"Pharmaceuticals and medical devices. Ministry of Health, Labour, and Welfare of Japan. 2019. URL: https:\/\/www.mhlw.go.jp\/english\/policy\/health-medical\/pharmaceuticals\/index.html [Accessed 20-07-2025]"},{"issue":"2","key":"R25","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19020892","article-title":"E-cigarettes use behaviors in Japan: an online survey","volume":"19","author":"Koyama","journal-title":"Int J Environ Res Public Health"},{"issue":"21","key":"R26","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17218030","article-title":"Reasons for regularly using heated tobacco products among adult current and former smokers in Japan: finding from 2018 ITC Japan survey","volume":"17","author":"Xu","journal-title":"Int J Environ Res Public Health"},{"issue":"8","key":"R27","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1016\/j.rmed.2008.02.017","article-title":"Common predictors of smoking cessation in clinical practice","volume":"102","author":"Caponnetto","journal-title":"Respir Med"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-018-0051-3","article-title":"The use of social features in mobile health interventions to promote physical activity: a systematic review","volume":"1","author":"Tong","journal-title":"NPJ Digit Med"},{"issue":"6","key":"R29","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17062098","article-title":"Concurrent daily and non-daily use of heated tobacco products with combustible cigarettes: findings from the 2018 ITC Japan survey","volume":"17","author":"Sutanto","journal-title":"Int J Environ Res Public Health"},{"issue":"6","key":"R30","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1136\/thoraxjnl-2020-216253","article-title":"Association of heated tobacco product use with tobacco use cessation in a Japanese workplace: a prospective study","volume":"76","author":"Kanai","journal-title":"Thorax"},{"issue":"1","key":"R31","doi-asserted-by":"publisher","first-page":"38","DOI":"10.4278\/0890-1171-12.1.38","article-title":"The transtheoretical model of health behavior change","volume":"12","author":"Prochaska","journal-title":"Am J Health Promot"},{"issue":"4","key":"R32","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1136\/tobaccocontrol-2020-056168","article-title":"Heated tobacco product use and combustible cigarette smoking relapse\/initiation among former\/never smokers in Japan: the JASTIS 2019 study with 1-year follow-up","volume":"31","author":"Matsuyama","journal-title":"Tob Control"},{"issue":"1","key":"R33","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013790.pub2","article-title":"Heated tobacco products for smoking cessation and reducing smoking prevalence","volume":"1","author":"Tattan-Birch","journal-title":"Cochrane Database Syst Rev"},{"issue":"15","key":"R34","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17155591","article-title":"Beliefs about the harmfulness of heated tobacco products compared with combustible cigarettes and their effectiveness for smoking cessation among Korean adults","volume":"17","author":"Kim","journal-title":"Int J Environ Res Public Health"},{"key":"R35","doi-asserted-by":"crossref","unstructured":"Yoshihara S Takahashi K Uemura C Murakami S Harada D Yamato H . Effectiveness of a digital peer-supported application intervention in promoting smoking cessation: non-randomized controlled trial. JMIR Preprints. Preprint posted online on Nov 11, 2024. [doi: 10.2196\/68638]","DOI":"10.2196\/68638"},{"issue":"2","key":"R36","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1080\/14622200210123581","article-title":"Biochemical verification of tobacco use and cessation","volume":"4","author":"Benowitz","journal-title":"Nicotine Tob Res"},{"key":"R37","unstructured":"Grammarly. 2025. URL: https:\/\/app.grammarly.com\/ [Accessed 03-06-2025]"},{"key":"R38","unstructured":"GPT-4. OpenAI. 2025. URL: https:\/\/openai.com\/index\/gpt-4-research\/ [Accessed 03-06-2025]"}],"container-title":["Journal of Medical Internet Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jmir.org\/2025\/1\/e75876","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:07:10Z","timestamp":1782842830000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jmir.org\/2025\/1\/e75876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,5]]},"references-count":38,"URL":"https:\/\/doi.org\/10.2196\/75876","relation":{},"ISSN":["1438-8871"],"issn-type":[{"value":"1438-8871","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,5]]},"article-number":"v27i6e75876"}}