{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:47:27Z","timestamp":1790315247896,"version":"4.1.0"},"reference-count":38,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Med Educ"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Physician empathy is important not only for improving patient satisfaction and health outcomes but also for increasing physician job satisfaction and protecting against burnout. However, amid concerns over declining empathy levels in medical education, there is a need for innovative teaching approaches that address the empathy gap, a critical element in patient-centered care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to use a mixed-methods analysis to explore the effectiveness of a virtual reality (VR) intervention versus traditional lecture methods in enhancing empathy among medical students.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Overall, 50 first- and second-year medical students were randomized to either a VR intervention, which simulated patient experiences, or a control group receiving traditional empathy lectures. Both groups watch 2 videos with reflections gathered after each video to capture students\u2019 experiential learning. Empathy was measured using the Jefferson Scale of Empathy-Student Version before and after the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Quantitative analysis revealed significant increases in empathy scores post intervention for both groups (lecture group: mean increase 4.71, SD 11.01; VR group: mean increase 5.6, SD 10.02;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001), indicating that both interventions enhanced empathy. The VR group exhibited a significant difference in qualitative empathy coding after the second video (\n                      <jats:italic>U<\/jats:italic>\n                      =165.5;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001) compared to the lecture group. Qualitative feedback from the VR group emphasized a more profound emotional and cognitive engagement with the patient perspective than the lecture group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study supports the integration of VR into medical education as a complementary approach to traditional teaching methods for empathy training. VR immersion provides a valuable platform for students to develop a deeper, more nuanced understanding of empathy. These findings advocate for further exploration into VR\u2019s long-term impact on empathy in clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/76504","type":"journal-article","created":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T14:50:07Z","timestamp":1764514207000},"page":"e76504-e76504","source":"Crossref","is-referenced-by-count":4,"title":["Investigating the Impact of a Virtual Reality Experience on Medical Student Empathy: Mixed Methods Study"],"prefix":"10.2196","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-4723-6756","authenticated-orcid":false,"given":"Allen G","family":"Mundok","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-2352-4319","authenticated-orcid":false,"given":"Vivian N","family":"Ho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3494-6334","authenticated-orcid":false,"given":"Lauren A","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3518-6314","authenticated-orcid":false,"given":"Ann Blair","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4830-2852","authenticated-orcid":false,"given":"Shannon","family":"Stark-Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"issue":"1","key":"R1","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1111\/j.1749-6632.2009.04418.x","article-title":"The social neuroscience of empathy","volume":"1156","author":"Singer","journal-title":"Ann N Y Acad Sci"},{"issue":"3","key":"R2","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1177\/0163278704267037","article-title":"The effects of physician empathy on patient satisfaction and compliance","volume":"27","author":"Kim","journal-title":"Eval Health Prof"},{"issue":"3","key":"R3","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1097\/ACM.0b013e3182086fe1","article-title":"Physicians\u2019 empathy and clinical outcomes for diabetic patients","volume":"86","author":"Hojat","journal-title":"Acad Med"},{"issue":"9","key":"R4","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1176\/appi.ajp.159.9.1563","article-title":"Physician empathy: definition, components, measurement, and relationship to gender and specialty","volume":"159","author":"Hojat","journal-title":"Am J Psychiatry"},{"issue":"9","key":"R5","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1111\/j.1365-2929.2004.01911.x","article-title":"An empirical study of decline in empathy in medical school","volume":"38","author":"Hojat","journal-title":"Med Educ"},{"issue":"8","key":"R6","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1097\/ACM.0b013e318299f3e3","article-title":"Teaching empathy to medical students: an updated, systematic review","volume":"88","author":"Batt-Rawden","journal-title":"Acad Med"},{"issue":"10","key":"R7","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1080\/0142159X.2017.1355451","article-title":"Empathy training in medical students - a randomized controlled trial","volume":"39","author":"W\u00fcndrich","journal-title":"Med Teach"},{"issue":"1","key":"R8","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1037\/0022-3514.93.1.65","article-title":"An additional antecedent of empathic concern: valuing the welfare of the person in need","volume":"93","author":"Batson","journal-title":"J Pers Soc Psychol"},{"issue":"4","key":"R9","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1002\/ejsp.163","article-title":"Perspective taking and prejudice reduction: the mediational role of empathy arousal and situational attributions","volume":"33","author":"Vescio","journal-title":"Euro J Social Psych"},{"issue":"5","key":"R10","doi-asserted-by":"publisher","first-page":"594","DOI":"10.1177\/0146167203262802","article-title":"The effects of perspective-taking on prejudice: the moderating role of self-evaluation","volume":"30","author":"Galinsky","journal-title":"Pers Soc Psychol Bull"},{"issue":"10","key":"R11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204494","article-title":"Building long-term empathy: a large-scale comparison of traditional and virtual reality perspective-taking","volume":"13","author":"Herrera","journal-title":"PLoS ONE"},{"issue":"6","key":"R12","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1111\/jcc4.12173","article-title":"Experiencing nature: embodying animals in immersive virtual environments increases inclusion of nature in self and involvement with nature","volume":"21","author":"Ahn","journal-title":"J Comput-Mediat Comm"},{"issue":"6","key":"R13","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1037\/a0037679","article-title":"Empathy: a motivated account","volume":"140","author":"Zaki","journal-title":"Psychol Bull"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.psych.51.1.93","article-title":"Social cognition: thinking categorically about others","volume":"51","author":"Macrae","journal-title":"Annu Rev Psychol"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1016\/j.chb.2016.02.007","article-title":"Virtually old: embodied perspective taking and the reduction of ageism under threat","volume":"60","author":"Oh","journal-title":"Comput Human Behav"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Sirkkunen E V\u00e4\u00e4t\u00e4j\u00e4 H Uskali T Rezaei PP . Journalism in virtual reality. Presented at: AcademicMindtrek\u201916; Oct 17-18, 2016:297-303; Tampere, Finland. [doi: 10.1145\/2994310.2994353]","DOI":"10.1145\/2994310.2994353"},{"issue":"9","key":"R17","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1097\/00001888-200409000-00004","article-title":"What is empathy, and how can it be promoted during clinical clerkships?","volume":"79","author":"Benbassat","journal-title":"Acad Med"},{"issue":"10","key":"R18","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1097\/00005053-199010000-00006","article-title":"The empathic process and its mediators. a heuristic model","volume":"178","author":"Gallop","journal-title":"J Nerv Ment Dis"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.10.009","article-title":"Are we really measuring empathy? Proposal for a new measurement framework","volume":"83","author":"Coll","journal-title":"Neurosci Biobehav Rev"},{"key":"R20","unstructured":"Creswell JW Plano Clark VL . Designing and Conducting Mixed Methods Research. 3rd ed. Sage Publications; 2017. URL: https:\/\/collegepublishing.sagepub.com\/products\/designing-and-conducting-mixed-methods-research-3-241842 [Accessed 30-12-2025] ISBN: 9781506394671"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2018.07.002","article-title":"The role of physiological arousal for self-reported emotional empathy","volume":"214","author":"Deuter","journal-title":"Auton Neurosci"},{"issue":"5","key":"R22","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s10459-018-9839-9","article-title":"The Jefferson Scale of Empathy: a nationwide study of measurement properties, underlying components, latent variable structure, and national norms in medical students","volume":"23","author":"Hojat","journal-title":"Adv Health Sci Educ Theory Pract"},{"issue":"10 Suppl","key":"R23","doi-asserted-by":"publisher","first-page":"S58","DOI":"10.1097\/00001888-200210001-00019","article-title":"The Jefferson Scale of Physician Empathy: further psychometric data and differences by gender and specialty at item level","volume":"77","author":"Hojat","journal-title":"Acad Med"},{"issue":"1","key":"R24","doi-asserted-by":"publisher","DOI":"10.1002\/nop2.2054","article-title":"Psychometric evaluation of the \u2018Jefferson Scale of Empathy\u2019 in a sample of nursing students in the United Kingdom","volume":"11","author":"Yu","journal-title":"Nurs Open"},{"issue":"5","key":"R25","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1007\/s10459-020-09965-y","article-title":"Empathy trajectories throughout medical school: relationships with personality and motives for studying medicine","volume":"25","author":"Piumatti","journal-title":"Adv Health Sci Educ Theory Pract"},{"issue":"8","key":"R26","doi-asserted-by":"publisher","first-page":"520","DOI":"10.7556\/jaoa.2019.091","article-title":"Empathy in medicine National norms for the Jefferson Scale of Empathy: a nationwide project in osteopathic medical education and empathy (POMEE)","volume":"119","author":"Hojat","journal-title":"J Am Osteopath Assoc"},{"key":"R27","doi-asserted-by":"crossref","unstructured":"Braun V Clarke V Terry G Hayfield N . Thematic analysis. In: Liamputtong P , editor. Handbook of Research Methods in Health and Social Sciences. Springer; 2019:843-860. [doi: 10.1007\/978-981-10-5251-4_103]","DOI":"10.1007\/978-981-10-5251-4_103"},{"key":"R28","unstructured":"Braun V Clarke V . Successful Qualitative Research: A Practical Guide for Beginners. SAGE Publications; 2013. URL: https:\/\/uk.sagepub.com\/en-gb\/eur\/successful-qualitative-research\/book233059 [Accessed 17-12-2025] ISBN: 9781847875815"},{"issue":"2","key":"R29","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"Braun","journal-title":"Qual Res Psychol"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6920-11-54","article-title":"Psychometric properties and confirmatory factor analysis of the Jefferson Scale of Physician Empathy","volume":"11","author":"Tavakol","journal-title":"BMC Med Educ"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1521\/soco.2014.32.supp.12","article-title":"On the other side of the mirror: priming in cognitive and social psychology","volume":"32","author":"Doyen","journal-title":"Soc Cogn"},{"issue":"3","key":"R32","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1037\/\/0022-3514.71.3.464","article-title":"Automatic activation of impression formation and memorization goals: nonconscious goal priming reproduces effects of explicit task instructions","volume":"71","author":"Chartrand","journal-title":"J Pers Soc Psychol"},{"key":"R33","doi-asserted-by":"crossref","unstructured":"Knowles MS Holton EF Swanson RA . The Adult Learner. 8th ed. Routledge; 2015. [doi: 10.4324\/9781315816951]","DOI":"10.4324\/9781315816951"},{"issue":"2","key":"R34","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1177\/1534582304267187","article-title":"The functional architecture of human empathy","volume":"3","author":"Decety","journal-title":"Behav Cogn Neurosci Rev"},{"issue":"119","key":"R35","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1002\/ace.309","article-title":"Adult learning theory for the twenty\u2010first century","volume":"2008","author":"Merriam","journal-title":"New Dir Adult Contin Educ"},{"issue":"1","key":"R36","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1089\/cyber.2017.29099.gri","article-title":"Neuroscience of virtual reality: from virtual exposure to embodied medicine","volume":"22","author":"Riva","journal-title":"Cyberpsychol Behav Soc Netw"},{"issue":"Pt 4","key":"R37","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1016\/j.neubiorev.2014.09.001","article-title":"Empathy: gender effects in brain and behavior","volume":"46 Pt 4","author":"Christov-Moore","journal-title":"Neurosci Biobehav Rev"},{"issue":"9","key":"R38","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-036471","article-title":"Assessing the effect of empathy-enhancing interventions in health education and training: a systematic review of randomised controlled trials","volume":"10","author":"Winter","journal-title":"BMJ Open"}],"container-title":["JMIR Medical Education"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/mededu.jmir.org\/2026\/1\/e76504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:08:04Z","timestamp":1782842884000},"score":1,"resource":{"primary":{"URL":"https:\/\/mededu.jmir.org\/2026\/1\/e76504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,4]]},"references-count":38,"URL":"https:\/\/doi.org\/10.2196\/76504","relation":{},"ISSN":["2369-3762"],"issn-type":[{"value":"2369-3762","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,4]]},"article-number":"v12i1e76504"}}