{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:49:59Z","timestamp":1790369399828,"version":"4.1.0"},"reference-count":42,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Previous research has demonstrated that the use of continuous glucose monitoring (CGM) can improve glycemic control in people with type 2 diabetes when used regularly alongside a digital diabetes self-management education and support (DSMES) program. However, to date, there is limited evidence showing the benefits of a digitally delivered DSMES program combined with real-time CGM for adults with type 2 diabetes.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n \n The objective of this study is to evaluate the impact of a DSMES program coupled with CGM on hemoglobin A\n 1c<\/jats:sub>\n (HbA\n 1c<\/jats:sub>\n ) and CGM-derived glycemic measures compared to usual care for adults with type 2 diabetes over 6 months.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Participants with type 2 diabetes and HbA\n 1c<\/jats:sub>\n of 8% or higher (64 mmol\/mol) who were not using mealtime bolus insulin (aged 26\u201083 y; mean HbA\n 1c<\/jats:sub>\n 9.6%, SD 1.4% [mean 81.2 mmol\/mol, SD 15.8 mmol\/mol]) were randomly assigned to a digital DSMES+CGM integrated solution (n=51) or usual care (n=49) for 6 months. The primary outcome was HbA\n 1c<\/jats:sub>\n . The secondary outcomes were CGM-derived glycemic measures, including glucose management indicator, percent time in range 70 to 180 mg\/dL, percent time above range (>180 mg\/dL), percent time below range (<70 mg\/dL), and mean glucose. Linear mixed effects models were used for intention-to-treat analyses.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n HbA\n 1c<\/jats:sub>\n was lower among the intervention group versus the usual care group at 3 months (difference=\u22120.7%, 95% CI \u22121.4% to \u22120.1% or difference=\u22128.1 mmol\/mol, 95% CI \u221215.5 to \u22120.7 mmol\/mol;\n P<\/jats:italic>\n =.03) and at 6 months (difference=\u22120.6%, 95% CI \u22121.4% to 0.2% or difference=\u22126.9 mmol\/mol, 95% CI \u221215.7 to 1.9 mmol\/mol;\n P<\/jats:italic>\n =.12) but only reached statistical significance at 3 months. CGM-derived glycemic measures, including glucose management indicator (difference=\u22120.9%, 95% CI \u22121.7% to \u22120.1%;\n P<\/jats:italic>\n =.03), time in range (difference=14.6%, 95% CI 1.0% to 28.2%;\n P<\/jats:italic>\n =.04), time above range (difference=\u221214.9%, 95% CI \u221229.0% to \u22120.9%;\n P<\/jats:italic>\n =.04), and mean glucose (difference=\u221236.4 mg\/dL, 95% CI \u221270.0 to \u22122.9 mg\/dL;\n P<\/jats:italic>\n =.03), also significantly improved for the intervention group versus the usual care group at 6 months.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The combination of digital DSMES+CGM is effective for supporting adults with type 2 diabetes in managing their condition and has the potential to reduce the risk of long-term health complications.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/78321","type":"journal-article","created":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T13:55:07Z","timestamp":1776002107000},"page":"e78321-e78321","source":"Crossref","is-referenced-by-count":1,"title":["A Digital Diabetes Self-Management Education and Support Program Integrated With Continuous Glucose Monitoring for Type 2 Diabetes: Randomized Controlled Trial"],"prefix":"10.2196","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5269-2924","authenticated-orcid":false,"given":"Ashley","family":"Berthoumieux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7014-2990","authenticated-orcid":false,"given":"Jeanean B","family":"Naqvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0802-2066","authenticated-orcid":false,"given":"Sean","family":"Zion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0271-5937","authenticated-orcid":false,"given":"Jenna","family":"Napoleone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6257-3793","authenticated-orcid":false,"given":"Amanda","family":"McGuill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2160-3148","authenticated-orcid":false,"given":"Christian J","family":"Cerrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8105-821X","authenticated-orcid":false,"given":"Hyun Jung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3487-2504","authenticated-orcid":false,"given":"Timothy C","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1335-1857","authenticated-orcid":false,"given":"David","family":"Kerr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3819-670X","authenticated-orcid":false,"given":"Carolyn Bradner","family":"Jasik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7129-3416","authenticated-orcid":false,"given":"Sarah","family":"Linke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"issue":"Suppl 1","key":"R1","doi-asserted-by":"publisher","first-page":"S20","DOI":"10.2337\/dc24-S002","article-title":"2. 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