{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:46:08Z","timestamp":1787024768303,"version":"build-2736575974"},"reference-count":20,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dementia is one of Canada\u2019s most pressing public health challenges, with rates expected to surge in response to the country\u2019s aging population. Given the rapidly growing issue of dementia, understanding national research efforts is critical to prioritizing and advancing strategic directions in brain health and dementia research. Recently, the Canadian Institutes of Health Research awarded a 1-year funding grant from the Brain Health and Cognitive Impairment in Aging Research Initiative to map the scope of brain health and dementia research in Canada.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This scoping review of reviews protocol aims to address this call by outlining the methodology that will be used for mapping the research landscape, documenting the knowledge gaps, and identifying areas of innovation to advance brain health and dementia research in Canada.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Given the large volume of literature, a scoping review of Canadian-led reviews was selected as the most appropriate method because it would allow for a robust synthesis of nationally relevant research while mapping knowledge gaps and innovation. Our scoping review of reviews will follow the framework by Arksey and O\u2019Malley along with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. The search will focus on peer-reviewed literature reviews published between January 1, 2020, and January 1, 2025, to capture the current state of knowledge since the national dementia strategy\u2019s publication in 2019. This search will be conducted using 5 electronic databases: CINAHL, PubMed, PsycInfo, Scopus, and Web of Science. Our data extraction table will include the following categories: author, province, and year; aim; review timeline; method; theme; knowledge gaps; innovations; and findings. The data will be analyzed using a combination of deductive and inductive thematic analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This protocol was registered on June 5, 2025, with the Open Science Framework. This study was funded by the Canadian Institutes of Health Research from November 2024 to November 2025. The anticipated timeline for the publication of the full scoping review of reviews is May 2026. The findings from this review will be shared through targeted knowledge mobilization activities such as presentations at national funding agency meetings, academic conferences, and community workshops.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our scoping review of reviews will provide a robust synthesis of the brain health and dementia research landscape, helping document critical knowledge gaps and identify areas for innovation. The results of this research will provide critical data to help inform strategic funding initiatives and future research directions. The findings from our scoping review will have implications for research funders, policymakers, community organizations, and researchers that are working to accelerate brain health and dementia research across Canada.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/79020","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T00:00:07Z","timestamp":1767830407000},"page":"e79020-e79020","source":"Crossref","is-referenced-by-count":2,"title":["Mapping the Landscape, Knowledge Gaps, and Areas for Innovation in Brain Health and Dementia Research in Canada: Protocol for a Scoping Review of Reviews"],"prefix":"10.2196","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2819-1617","authenticated-orcid":false,"given":"Juanita-Dawne","family":"Bacsu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6872-5841","authenticated-orcid":false,"given":"Kiana","family":"Mero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6159-4322","authenticated-orcid":false,"given":"Megan E","family":"O'Connell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8306-4629","authenticated-orcid":false,"given":"Megan","family":"Funk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5509-8960","authenticated-orcid":false,"given":"Alixe","family":"M\u00e9nard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8588-0162","authenticated-orcid":false,"given":"Myrna","family":"Norman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9637-5488","authenticated-orcid":false,"given":"Sheila","family":"Blackstock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7048-7844","authenticated-orcid":false,"given":"Jim","family":"Mann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7506-459X","authenticated-orcid":false,"given":"Wendy","family":"Hulko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3156-0663","authenticated-orcid":false,"given":"Melba Sheila","family":"D\u2019Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4291-6298","authenticated-orcid":false,"given":"Sarah","family":"Fraser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"R1","unstructured":"Dementia numbers in Canada. Alzheimer Society. 2025. URL: https:\/\/alzheimer.ca\/en\/about-dementia\/what-dementia\/dementia-numbers-canada [Accessed 24-01-2025]"},{"key":"R2","unstructured":"Dementia: overview. Government of Canada. 2025. URL: https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/dementia.html [Accessed 09-11-2025]"},{"key":"R3","unstructured":"Dementia: risk factors and prevention. Government of Canada. 2025. URL: https:\/\/www.canada.ca\/en\/public-health\/services\/diseases\/dementia\/risk-factors-prevention.html [Accessed 05-11-2025]"},{"key":"R4","unstructured":"Dementia in Canada: summary. Canadian Institute for Health Information. URL: https:\/\/www.cihi.ca\/en\/dementia-in-canada\/dementia-in-canada-summary [Accessed 03-06-2025]"},{"key":"R5","unstructured":"The older people are all right. Statistics Canada. 2024. URL: https:\/\/www.statcan.gc.ca\/o1\/en\/plus\/7059-older-people-are-all-right [Accessed 18-01-2025]"},{"key":"R6","unstructured":"Navigating the path forward for dementia in Canada. Alzheimer Society Canada. 2022. URL: https:\/\/alzheimer.ca\/sites\/default\/files\/documents\/Landmark-Study-Report-1-Path_Alzheimer-Society-Canada_0.pdf [Accessed 08-11-2025]"},{"key":"R7","unstructured":"Dementia in Canada: economic burden 2020 to 2050. Canadian Centre for Economic Analysis. 2023. URL: https:\/\/www.cancea.ca\/wp-content\/uploads\/2023\/07\/CANCEA-Economic-Impact-of-Dementia-in-Canada-2023-01-08.pdf [Accessed 25-01-2026]"},{"issue":"4","key":"R8","doi-asserted-by":"publisher","first-page":"340","DOI":"10.5770\/cgj.23.426","article-title":"Improving dementia care among family physicians: from stigma to evidence-informed knowledge","volume":"23","author":"Bacsu","journal-title":"Can Geriatr J"},{"key":"R9","unstructured":"Dementia. World Health Organization. 2025. 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