{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:06:54Z","timestamp":1782846414981,"version":"3.54.5"},"reference-count":10,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Dermatol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Dermal fillers are commonly used for facial augmentation, but delayed complications such as granulomatous inflammation and filler migration can mimic chronic bacterial infections, such as cervicofacial actinomycosis, and lead to diagnostic misdirection. We present the case of a woman aged 56 years with a chronic, draining abscess on the right cheek that persisted for 3 years and was initially suspected to represent cervicofacial actinomycosis. Tissue cultures were negative, and histopathologic analysis following excisional biopsy revealed polymethyl methacrylate microspheres and hyaluronic acid surrounded by granulomatous inflammation and reactive lymphoid aggregates, consistent with a foreign body reaction to dermal filler. The patient experienced complete resolution after surgical excision. This case underscores the diagnostic challenges posed by delayed filler complications and highlights the importance of considering prior cosmetic procedures in patients with chronic facial abscesses.<\/jats:p>","DOI":"10.2196\/80278","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:40:07Z","timestamp":1766709607000},"page":"e80278-e80278","source":"Crossref","is-referenced-by-count":0,"title":["Chronic Facial Abscess Mimicking Cervicofacial Actinomyces From Dermal Filler Migration: Case Report"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2306-5782","authenticated-orcid":false,"given":"Monika","family":"Ziogaite","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3506-904X","authenticated-orcid":false,"given":"Sarah","family":"Mannlein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3931-9839","authenticated-orcid":false,"given":"Nicole","family":"Bender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7020-3506","authenticated-orcid":false,"given":"Scott J","family":"Mahlberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"issue":"4","key":"R1","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/j.det.2009.08.003","article-title":"Semipermanent and permanent injectable fillers","volume":"27","author":"Jones","journal-title":"Dermatol Clin"},{"issue":"15","key":"R2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14151640","article-title":"Review of the adverse effects associated with dermal filler treatments: part I nodules, granuloma, and migration","volume":"14","author":"Hong","journal-title":"Diagnostics (Basel)"},{"issue":"3","key":"R3","doi-asserted-by":"publisher","first-page":"256","DOI":"10.4103\/JCAS.JCAS_194_20","article-title":"Giant PMMA foreign body granulomas with imaging","volume":"16","author":"Sivam","journal-title":"J Cutan Aesthet Surg"},{"issue":"2","key":"R4","doi-asserted-by":"publisher","first-page":"232","DOI":"10.5999\/aps.2015.42.2.232","article-title":"Foreign body granulomas after the use of dermal fillers: pathophysiology, clinical appearance, histologic features, and treatment","volume":"42","author":"Lee","journal-title":"Arch Plast Surg"},{"issue":"4","key":"R5","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.fsc.2015.07.006","article-title":"Facial filler complications","volume":"23","author":"Woodward","journal-title":"Facial Plast Surg Clin North Am"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S50546","article-title":"Dermal fillers in aesthetics: an overview of adverse events and treatment approaches","volume":"6","author":"Funt","journal-title":"Clin Cosmet Investig Dermatol"},{"issue":"2","key":"R7","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1093\/asj\/sjv195","article-title":"Complications and management of polymethylmethacrylate (PMMA) injections to the midface","volume":"36","author":"Limongi","journal-title":"Aesthet Surg J"},{"issue":"4","key":"R8","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.clindermatol.2011.06.027","article-title":"Actinomycetoma and advances in its treatment","volume":"30","author":"Welsh","journal-title":"Clin Dermatol"},{"issue":"6","key":"R9","doi-asserted-by":"publisher","first-page":"1842","DOI":"10.1097\/PRS.0b013e31818236d7","article-title":"Foreign body granulomas after all injectable dermal fillers: part 1. Possible causes","volume":"123","author":"Lemperle","journal-title":"Plast Reconstr Surg"},{"issue":"9","key":"R10","first-page":"1053","volume":"13","author":"Rao","journal-title":"J Drugs Dermatol"}],"container-title":["JMIR Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/derma.jmir.org\/2026\/1\/e80278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:13:40Z","timestamp":1782843220000},"score":1,"resource":{"primary":{"URL":"https:\/\/derma.jmir.org\/2026\/1\/e80278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":10,"URL":"https:\/\/doi.org\/10.2196\/80278","relation":{},"ISSN":["2562-0959"],"issn-type":[{"value":"2562-0959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]},"article-number":"v9i4e80278"}}