{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:06:54Z","timestamp":1782846414846,"version":"3.54.5"},"reference-count":49,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Depression and anxiety can significantly impact workplace productivity, for instance, by increasing absenteeism and presenteeism. This loss of productivity leads to diminished workplace economic outcomes. Internet-based cognitive behavioral therapy (iCBT) has emerged as a cost-effective intervention within workplace settings that improves workplace productivity loss due to depression and anxiety, but more generalizable evidence beyond the workplace, such as in a national health service setting, is lacking.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This naturalistic, repeated-measures, retrospective study investigated the impact of iCBT on work productivity metrics using nationally representative data from patients enrolled in the Irish national health service (ie, the Health Service Executive).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed repeated measures retrospective data from 7125 employed patients enrolled in iCBT at the Health Service Executive between March 2023 and May 2024. The Work Productivity and Activity Impairment questionnaire was used to measure absenteeism, presenteeism, overall productivity loss, and activity impairment. Secondary outcomes included depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7). Patients were primarily 25 to 64 years old (n=5578, 78%), female (n=4956, 70%), and met clinical scoring criteria on the Patient Health Questionnaire-9 or Generalized Anxiety Disorder-7 (n=4774, 67%). Missing data were handled using multiple imputation. We used mixed-effects models to assess pre-post treatment changes in outcomes and then utilized Irish national salary estimates from 2022 to derive cost savings (in 2022 \u20ac values; \u20ac1=approximately US $1.05) based on productivity improvement during use of the iCBT program.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      From baseline to follow-up, absenteeism reduced by 6.85% (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 5.79%\u20107.91%, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.21), presenteeism reduced by 5.84% (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 4.59%\u20107.09%, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.18), productivity loss reduced by 9.48% (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 8.30%\u201010.66%, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.27), and activity impairment reduced by 8.34% (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 7.07%\u20109.61%, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.30). Depression symptom scores reduced by 2.70 points (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 2.50\u20102.90, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.51) and anxiety symptom scores reduced by 2.71 points (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001, 95% CI 2.51\u20102.91, Cohen\n                      <jats:italic>d<\/jats:italic>\n                      =0.52) scores posttreatment. Larger reductions in depression and anxiety symptoms were linked to greater improvements in workplace functioning outcomes (\n                      <jats:italic>r<\/jats:italic>\n                      =0.06-0.34, all\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001). Patients with higher baseline clinical severity experienced approximately 6% greater improvements in workplace productivity than subclinical patients (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001). These improvements in work productivity from baseline to follow-up corresponded to more than \u20ac4000 annual savings per patient treated, which equated to an estimated annual savings of \u20ac29 million in the sample (in 2022 \u20ac values). The average currency exchange rate in 2022 would be \u20ac1 to approximately US $1.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Building on work that primarily focused on work productivity improvements from iCBT in occupational contexts, this study provides evidence that iCBT for the general adult population in a national routine health care setting is associated with improvements in both Common mental disorders (CMD) and workplace productivity losses associated with CMD. These productivity improvements were further associated with sizable cost savings. These findings suggest that integrating iCBT into national mental health infrastructure can be a feasible, scalable solution, which could generate clinical and economic benefits at a population level.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/80689","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T14:00:15Z","timestamp":1767621615000},"page":"e80689-e80689","source":"Crossref","is-referenced-by-count":0,"title":["Changes in Workplace Productivity and Estimated Cost Savings During Internet-Based Cognitive Behavioral Therapy in the Irish National Health Service: Naturalistic, Repeated-Measures, Retrospective Survey Study"],"prefix":"10.2196","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3404-5368","authenticated-orcid":false,"given":"Chi Tak","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7560-9185","authenticated-orcid":false,"given":"Siobh\u00e1n","family":"Harty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-4008","authenticated-orcid":false,"given":"Angel","family":"Enrique","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7440-1480","authenticated-orcid":false,"given":"Alba","family":"Jim\u00e9nez-D\u00edaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7099-8417","authenticated-orcid":false,"given":"Garrett","family":"Hisler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9722-0437","authenticated-orcid":false,"given":"Daniel","family":"Duffy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0871-4078","authenticated-orcid":false,"given":"Derek","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"R1","unstructured":"World mental health report: transforming mental health for all. 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