{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:39:11Z","timestamp":1792175951405,"version":"4.4.0"},"reference-count":48,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Aging"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Mild cognitive impairment (MCI) is an intermediate state between normal aging and dementia, characterized by subjective cognitive decline and objective memory impairment. Cognitive training has consistently shown short-term benefits for individuals with MCI, but evidence on the long-term effectiveness is extremely limited. Given the progressive nature of MCI and the need for sustainable strategies to delay cognitive decline, research on the long-term impact of cognitive training is necessary and timely. Mobile-based platforms offer a promising solution by enhancing accessibility and adherence, but their durability of effect over extended periods remains underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to evaluate the long-term effects of a mobile-based cognitive training app on the cognitive function of older adults with MCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In total, 28 older adults with MCI used Cogthera, a mobile cognitive training app based on metamemory training. Participants completed 2 training sessions daily for 3 months, and 9 (32%) continued for an additional 12 months. Cognitive function and quality of life were assessed using the Alzheimer\u2019s Disease Assessment Scale-Cognitive Subscale 14 and EQ-5D-5L.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Cognitive function improved over 15 months, as measured by Alzheimer\u2019s Disease Assessment Scale-Cognitive Subscale (F2,35.56=7.08; P=.003). EQ-5D-5L scores increased at 3 months but did not show sustained change at 15 months (F2,42.14=3.40; P=.04). Greater cognitive improvements were associated with younger age, higher functional status, and lower baseline cognitive function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study showed that long-term use of a mobile-based metamemory cognitive training app was associated with cognitive improvements over 15 months. Although limited by the small sample size and the absence of a control group, these findings suggest potential for mobile cognitive training as a sustainable intervention that warrants validation in larger trials.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/81648","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T21:35:10Z","timestamp":1764970510000},"page":"e81648","source":"Crossref","is-referenced-by-count":2,"title":["Long-Term Effects of Mobile-Based Metamemory Cognitive Training in Older Adults With Mild Cognitive Impairment: 15-Month Prospective Single-Arm Longitudinal 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