{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:06:22Z","timestamp":1782846382850,"version":"3.54.5"},"reference-count":60,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Hum Factors"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Informal caregivers (ICs), often family members or close friends, provide essential support to individuals with head and neck cancer. However, they are frequently unprepared for the emotional, practical, and medical challenges involved. Web-based applications offer promising opportunities to support ICs, but their long-term adoption and acceptance remain uncertain.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This paper presents the development of Carer eSupport, a web-based application to support ICs\u2019 well-being and preparedness for caregiving. We detail the design and functionality of the Carer eSupport application and explain how it responds to both the functional and psychological needs of ICs. Additionally, we report findings from the pilot study and highlight the initial challenges ICs faced when engaging with the application, along with the strategies used to overcome them.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The study involved a multicenter research trial across ear, nose, and throat clinics and oncology and radiotherapy clinics at 4 university hospitals in Sweden. The application was developed through 3 human-centered design (HCD) iterations involving ICs, health care professionals, and researchers in human-computer interaction and cancer care.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The results present an overview of the current version of Carer eSupport (developed during the third design iteration), with a focus on features that address the psychological needs of ICs, including competence, autonomy, and a sense of connection to others. The pilot study achieved a 66.7% (20\/30) consent rate, a 75% (9\/12) successful login rate among participants, and a 13.3% (4\/30) attrition rate, meeting the established criteria. The pilot study confirmed the application\u2019s readiness for further evaluation in an ongoing randomized controlled trial. It also identified challenges, including the time constraints of ICs, login and authentication issues, limited IT infrastructure, and gaps in digital literacy.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Findings from the HCD process and pilot study indicate that a personalized, interactive application like Carer eSupport can provide meaningful support for ICs of individuals with head and neck cancer. The integration of HCD and health care science offers early guidance for developing digital tools that are both evidence-based and empathetic, with potential relevance beyond caregiving contexts.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/81896","type":"journal-article","created":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:09Z","timestamp":1772323209000},"page":"e81896-e81896","source":"Crossref","is-referenced-by-count":0,"title":["The Development of a Web-Based Application to Support Informal Caregivers of Individuals With Head and Neck Cancer: Human-Centered Design Approach"],"prefix":"10.2196","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6947-9409","authenticated-orcid":false,"given":"Awais","family":"Ahmad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7472-2215","authenticated-orcid":false,"given":"\u00c5sa","family":"Cajander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8174-579X","authenticated-orcid":false,"given":"Ulrica","family":"Langeg\u00e5rd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6226-6849","authenticated-orcid":false,"given":"Birgitta","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2631-7757","authenticated-orcid":false,"given":"Anna","family":"Henriksson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3294-081X","authenticated-orcid":false,"given":"Mona","family":"Pettersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7601-2181","authenticated-orcid":false,"given":"Waqas","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7435-167X","authenticated-orcid":false,"given":"Ylva","family":"Tiblom Ehrsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"issue":"4","key":"R1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.55708\/js0104014","article-title":"Human-computer interaction for older adults - a literature review on technology acceptance of eHealth systems","volume":"1","author":"Ahmad","journal-title":"J Eng Res Sci"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.70389\/PJPH.100010","article-title":"Adapting health systems for an aging world: policy innovations and global strategies","volume":"24","author":"Wheatley","journal-title":"Prem J Public Health"},{"issue":"5","key":"R3","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-057442","article-title":"Internet-based support for informal caregivers to individuals with head and neck cancer (Carer eSupport): a study protocol for the development and feasibility testing of a complex online intervention","volume":"12","author":"Langeg\u00e5rd","journal-title":"BMJ Open"},{"issue":"2","key":"R4","doi-asserted-by":"publisher","first-page":"e122","DOI":"10.1200\/JOP.18.00522","article-title":"Population-based profile of mental health and support service need among family caregivers of adults with cancer","volume":"15","author":"Kent","journal-title":"J Oncol Pract"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Hudson P Payne S . 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