{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T19:08:23Z","timestamp":1782846503050,"version":"3.54.5"},"reference-count":45,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>HIV\/AIDS is a disease associated with stigma and discrimination. This can hinder the adoption of preventive and treatment methods, especially in vulnerable populations, such as the transgender community.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The primary objectives of this study are to explore awareness barriers related to HIV\/AIDS, develop and pilot a mobile-based HIV awareness app, and evaluate its acceptability and usability within the transgender community.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The research will employ a quasi-experimental design, utilizing a pre- and posttest comparison between an intervention group that will use the mobile app and a comparison group that will not. Phase 1 involves a situational analysis, including key informant interviews, focus group discussions, and a cross-sectional survey. An app will be designed and developed in Phase 2. Phase 3 will comprise a preintervention assessment recruiting 150 transgender people, implementation of the app on the cell phones of 75 transgender people, and a postapp assessment. Statistical techniques will be employed to analyze the captured data and assess the effectiveness of the app.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The recruitment began on August 25, 2025, for the first phase, with the subsequent phases to follow. The data collection and analysis will be completed and finalized by August 31, 2026, following the intervention deployment. No funding was received from any external source for this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of this study will reveal the effectiveness of a mobile app for the transgender community. These results will determine the continuation and further scale-up of this intervention. The findings will create evidence to inform favorable strategies for vulnerable populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>International Registered Report Identifier (IRRID)<\/jats:title>\n                    <jats:p>DERR1-10.2196\/84610<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/84610","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T18:45:07Z","timestamp":1771440307000},"page":"e84610","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of a Digital Awareness App in HIV\/AIDS Mitigation Among Transgender Individuals in Rawalpindi District: Protocol for a Quasi-Experimental Study"],"prefix":"10.2196","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0192-1758","authenticated-orcid":false,"given":"Muhammad 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of the contribution of the UNAIDS joint program to strengthening HIV and primary health care outcomesUNAIDS2024-11-16http:\/\/www.unaids.org\/en\/whoweare\/evaluation"},{"key":"ref4","unstructured":"Understanding measures of progress towards the 95-95-95 HIV testing, treatment and viral suppression targetsUNAIDS2024-11-16https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/progress-towards-95-95-95_en.pdf"},{"key":"ref5","unstructured":"HIV and AIDSWorld Health Organization20242024-11-16https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/hiv-aids"},{"key":"ref6","unstructured":"BhattiWaqarData of Pakistan\u2019s $3.2m HIV survey under fire for \u2018fabrication\u2019The News20252025-06-17Islamabadhttps:\/\/www.thenews.com.pk\/print\/1322070-data-of-pakistan-s-3-2m-hiv-survey-under-fire-for-fabrication.com"},{"key":"ref7","unstructured":"Integrated biological and behavioral surveillanceGovernment of Pakistan (Common Management 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