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This study found that engagement differed by content type, with response-style videos performing best and educational videos performing worst; in multivariate analysis, patient-created videos were also associated with higher engagement, while educational depth was not associated with engagement, suggesting that format, relatability, and presentation style may influence audience engagement more than educational depth, highlighting potential opportunities to improve the reach and inclusivity of melanoma-related health communication.<\/jats:p>","DOI":"10.2196\/87064","type":"journal-article","created":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:55:06Z","timestamp":1783212906000},"page":"e87064-e87064","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of Melanoma Educational Content and Skin of Color Representation on TikTok: Cross-Sectional Study"],"prefix":"10.2196","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4444-0640","authenticated-orcid":false,"given":"Daniella","family":"Jaguan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9552-6017","authenticated-orcid":false,"given":"Zoya","family":"Siddiqui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4897-3277","authenticated-orcid":false,"given":"Jennifer Nam","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"issue":"1","key":"R1","doi-asserted-by":"publisher","first-page":"5996","DOI":"10.1038\/s41598-025-90485-3","article-title":"Global, regional, and national trends in the burden of melanoma and non-melanoma skin cancer: insights from the Global Burden of Disease Study 1990\u20132021","volume":"15","author":"Zhou","journal-title":"Sci Rep"},{"issue":"6","key":"R2","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14098","article-title":"Internet and social media use in dermatology patients: search behavior and impact on patient-physician relationship","volume":"33","author":"Gantenbein","journal-title":"Dermatol Ther"},{"key":"R3","unstructured":"Time spent on TikTok per day - 95 min on average in 2026. 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