{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:43:06Z","timestamp":1785544986844,"version":"3.56.0"},"reference-count":28,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Nurse-initiated management of antiretroviral therapy (NIMART) has expanded access to life-saving antiretroviral therapy and enhanced the decentralization of HIV care. The psychobiological and psychosocial responses of nurses implementing this strategy have been largely underexplored.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This scoping review aims to systematically map the extent, nature, and characteristics of the existing literature on the psychobiological and psychosocial responses of NIMART-trained nurses providing care to people living with HIV.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The review will be conducted in accordance with the Joanna Briggs Institute methodology and the population, concept, and context (PCC) framework, which will guide the development of the review question and define the eligibility criteria. A comprehensive search strategy will be used to identify empirical studies published between 2010 and 2026 across electronic databases (PubMed, SABINET, PsycInfo, CINAHL, Scopus, and Google Scholar). Two independent reviewers will screen the titles and abstracts to determine which studies are eligible. If there is any disagreement, a third reviewer will resolve it. Data will be analyzed using narrative synthesis and thematic mapping to identify patterns, knowledge gaps, and implications for future research, practice, and policy.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The review is expected to identify the scope, trends, and gaps in the literature on psychobiological and psychosocial responses among NIMART-trained nurses. The estimated outcomes will include a synthesis of existing evidence. The scoping review was initiated in July 2025, and is expected to be completed by the end of July 2026.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This scoping review will provide an evidence-based understanding of the psychobiological and psychosocial responses of NIMART-trained nurses, highlighting implications for policy, practice, workforce support, and future research.<\/jats:p>\n <\/jats:sec>","DOI":"10.2196\/87562","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T18:12:13Z","timestamp":1784657533000},"page":"e87562-e87562","source":"Crossref","is-referenced-by-count":0,"title":["Psychobiological and Psychosocial Responses of Nurse-Initiated Management of Antiretroviral Therapy\u2013Trained Nurses Caring for People Living With HIV: Protocol for a Scoping Review"],"prefix":"10.2196","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1415-9183","authenticated-orcid":false,"given":"Phodzo Desire","family":"Tshelani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9683-2842","authenticated-orcid":false,"given":"Muimeleli","family":"Munyadziwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1689-9308","authenticated-orcid":false,"given":"Lufuno","family":"Makhado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,7,21]]},"reference":[{"key":"R1","unstructured":"The path that ends AIDS: UNAIDS global AIDS update 2023. 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