{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:33:51Z","timestamp":1791232431618,"version":"4.1.0"},"reference-count":111,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Med Internet Res"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Health systems worldwide face growing pressure from population aging, multimorbidity, and rising emergency admissions, prompting reconsideration of traditional inpatient care models. In response, digitally enabled models such as tele\u2013intensive care unit (tele-ICU) programs, hospital-at-home services, virtual wards, and other remote specialist pathways have expanded, particularly after the COVID-19 pandemic accelerated telemedicine adoption and cross-site virtual staffing. However, nationally coordinated, multispecialty virtual hospitals remain uncommon worldwide, and robust evidence on their system-level effects is still limited. As a result, policy discussions about national virtual hospitals must often draw on evidence from related virtual-care models rather than from mature national implementations. This viewpoint synthesizes representative international evidence from tele-ICU systems, hospital-at-home programs, virtual wards, telestroke networks, and other condition-specific virtual-care pathways, and examines Saudi Arabia\u2019s Seha Virtual Hospital (SVH) as a national case study to identify policy lessons relevant to the design, governance, and evaluation of national virtual hospitals. Across settings, these models suggest that remote and digitally supported care can achieve outcomes comparable to in-person hospital care when patient selection is appropriate, escalation and transfer pathways are explicit, monitoring intensity matches clinical risk, and multidisciplinary teams are integrated into local workflows. Tele-ICU programs have reported reductions in intensive care mortality and length of stay under well-structured organizational models, while hospital-at-home and virtual-ward programs have shown comparable safety, reduced hospital usage, and improved patient experience among selected patient groups. Telestroke networks likewise demonstrate outcomes comparable to specialist in-person care in acute stroke pathways. Nevertheless, the evidence base remains heterogeneous and strongly context-dependent. Much of the literature is short-term, with limited consistent evidence on long-term outcomes, caregiver burden, cost-effectiveness, workforce implications, and digital equity. SVH illustrates the emerging implementation of a centralized national virtual hospital model. Launched in 2022 under Saudi Arabia\u2019s Vision 2030 Health Sector Transformation Program, SVH operates as a national telehealth hub embedded within the country\u2019s broader digital-health ecosystem and links hospitals across the Kingdom to specialized clinical expertise. Its service portfolio includes urgent and critical care consultations, specialized virtual clinics, multidisciplinary case discussions, and supportive diagnostic services. Early reports indicate rapid operational expansion, broad institutional participation, and national-scale feasibility. However, independent comparative evidence evaluating SVH\u2019s effects on mortality, readmissions, length of stay, cost-effectiveness, equity, and workforce sustainability remains limited. National virtual hospitals should therefore be understood as evidence-generating health-system innovations rather than fully validated care models. Sustainable scale-up requires embedding rigorous prospective evaluation within implementation, aligning financing mechanisms with substitution of inpatient care, establishing clear governance and regulatory frameworks, and addressing digital inclusion and workforce sustainability. These considerations can help guide policymakers and health-system leaders in the accountable, equitable, and evidence-informed development of national virtual hospital programs.<\/jats:p>","DOI":"10.2196\/89276","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:45:08Z","timestamp":1779259508000},"page":"e89276-e89276","source":"Crossref","is-referenced-by-count":1,"title":["Policy Considerations for National Virtual Hospitals: Global Evidence and the Seha Virtual Hospital Model"],"prefix":"10.2196","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6250-2650","authenticated-orcid":false,"given":"Sohaib","family":"Shujaat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0561-1838","authenticated-orcid":false,"given":"Hawazin","family":"Almutairi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-5968-4060","authenticated-orcid":false,"given":"Saleh Hamad","family":"Alhuraibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1645-312X","authenticated-orcid":false,"given":"Hongyang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,6,22]]},"reference":[{"issue":"1","key":"R1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-024-03572-z","article-title":"Has multimorbidity and frailty in adult hospital admissions changed over the last 15 years? 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