{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:20:03Z","timestamp":1788286803832,"version":"build-2803163510"},"reference-count":34,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Mhealth Uhealth"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Optimal bowel preparation (BP) is crucial for a successful colonoscopy. Although multiple factors influence BP quality, including patient adherence to laxatives and dietary instructions, the stool state during BP should be properly evaluated to perform a colonoscopy of sufficient quality. Therefore, we developed a smartphone app to evaluate a patient\u2019s stool state during BP and a viewer to enable real-time monitoring by medical staff.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to assess the feasibility of performing colonoscopies of appropriate quality using the app-and-viewer system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective observational study was conducted between November 2022 and December 2023, involving patients scheduled for colonoscopy at 10 Japanese institutions, comprising 6 tertiary hospitals, 3 regional general hospitals, and 1 community-based clinic. Patients who (1) underwent a colonoscopy at participating institutions, (2) were aged between 20 and 70 years, and (3) owned smartphones compatible with Android or iOS were included in the study. The patients downloaded the app on their smartphones and captured images of their stools during BP, while the medical staff reviewed the evaluation of the stools by the app via the viewer system. The primary end point was defined as the proportion of patients with a Boston Bowel Preparation Scale (BBPS) score of \u22656 among those who successfully used the app. Secondary end points included mean BBPS score, rate of an excellent BBPS score (\u22658), adenoma detection rate, cecal intubation rate, and withdrawal time in negative colonoscopy. Additionally, we evaluated the usability of the app, medical staff workload burden with the app, and viewer usage via questionnaire surveys.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 343 patients were enrolled, and 326 were ultimately included in the analysis. Overall, 99.1% (323\/326, 95% CI 97.3%-99.8%) of the patients achieved the primary end point. The mean BBPS score was 8.5 (SD 1.0), and the proportion of excellent BBPS scores was 87.4% (285\/326). The adenoma detection rate, cecal intubation rate, and mean withdrawal time in negative colonoscopy were 46.9% (153\/326, 95% CI 41.4%-52.5%), 99.7% (325\/326, 95% CI 98.3%-99.9%), and 10.7 (SD 5.9) minutes, respectively. In the questionnaire survey, 98.5% (321\/326) of the patients reported that the tutorial was easy to understand, 96.0% (313\/326) found stool image capture easy, and 87.8% (286\/326) reported reduced anxiety regarding BP. Furthermore, 90.5% (295\/326) of the patients indicated that they would like to use the app again for future colonoscopies. Among medical staff, 92.5% (62\/67) considered the viewer system necessary, 89.6% (60\/67) found it easy to use, and 89.6% (60\/67) reported a reduction in workload burden.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AI-based stool state assessment using the app and the viewer during BP was feasible across diverse BP methods and clinical environments. Favorable BP outcomes and high usability among patients and medical staff support the potential use of this approach in real-world colonoscopy practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/91274","type":"journal-article","created":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:12:30Z","timestamp":1788286350000},"page":"e91274-e91274","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of a Stool State Check App Using AI During Bowel Preparation Before Colonoscopy: Multicenter Prospective Study (SCAN Study)"],"prefix":"10.2196","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7036-9485","authenticated-orcid":false,"given":"Atsushi","family":"Inaba","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8786-4634","authenticated-orcid":false,"given":"Kensuke","family":"Shinmura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4272-6358","authenticated-orcid":false,"given":"Shozo","family":"Osera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8276-0641","authenticated-orcid":false,"given":"Takahiro","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9452-8444","authenticated-orcid":false,"given":"Hiroaki","family":"Kon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4531-8341","authenticated-orcid":false,"given":"Maki","family":"Kanazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2630-8076","authenticated-orcid":false,"given":"Naoki","family":"Sugimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3352-5757","authenticated-orcid":false,"given":"Yasushi","family":"Sano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3483-5351","authenticated-orcid":false,"given":"Hiroko","family":"Hosaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4425-4331","authenticated-orcid":false,"given":"Toshio","family":"Uraoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8528-2315","authenticated-orcid":false,"given":"Daiki","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8488-4303","authenticated-orcid":false,"given":"Yusuke","family":"Yoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7019-6331","authenticated-orcid":false,"given":"Hiroyuki","family":"Takamaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9574-7451","authenticated-orcid":false,"given":"Yutaka","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0756-8355","authenticated-orcid":false,"given":"Toshihiko","family":"Gocho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-5135","authenticated-orcid":false,"given":"Atsushi","family":"Katagiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0494-9427","authenticated-orcid":false,"given":"Kazuhisa","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9244-2820","authenticated-orcid":false,"given":"Takahisa","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2963-9513","authenticated-orcid":false,"given":"Atsuki","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3814-0418","authenticated-orcid":false,"given":"Hitomi","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8236-8062","authenticated-orcid":false,"given":"Hiroki","family":"Matsuzaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8089-7433","authenticated-orcid":false,"given":"Nobuyoshi","family":"Takeshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6368-5671","authenticated-orcid":false,"given":"Masashi","family":"Wakabayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9840-4588","authenticated-orcid":false,"given":"Hiroaki","family":"Ikematsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8030-1449","authenticated-orcid":false,"given":"Tomonori","family":"Yano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,9,1]]},"reference":[{"issue":"1","key":"R1","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1053\/j.gastro.2020.02.068","article-title":"Global burden of 5 major types of gastrointestinal cancer","volume":"159","author":"Arnold","journal-title":"Gastroenterology"},{"issue":"20","key":"R2","doi-asserted-by":"publisher","first-page":"2366","DOI":"10.1001\/jama.295.20.2366","article-title":"Risk of developing colorectal cancer following a negative colonoscopy examination: evidence for a 10-year interval between colonoscopies","volume":"295","author":"Singh","journal-title":"JAMA"},{"issue":"21","key":"R3","doi-asserted-by":"publisher","first-page":"2664","DOI":"10.1200\/JCO.2011.40.4772","article-title":"Association between colonoscopy and colorectal cancer mortality in a US cohort according to site of cancer and colonoscopist specialty","volume":"30","author":"Baxter","journal-title":"J Clin Oncol"},{"issue":"12","key":"R4","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1056\/NEJMoa1301969","article-title":"Long-term colorectal-cancer incidence and mortality after lower endoscopy","volume":"369","author":"Nishihara","journal-title":"N Engl J Med"},{"issue":"4","key":"R5","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1053\/j.gastro.2007.07.006","article-title":"Five-year colon surveillance after screening colonoscopy","volume":"133","author":"Lieberman","journal-title":"Gastroenterology"},{"issue":"28","key":"R6","doi-asserted-by":"publisher","first-page":"3761","DOI":"10.1200\/JCO.2011.35.9307","article-title":"Long-term risk of colorectal cancer after negative colonoscopy","volume":"29","author":"Brenner","journal-title":"J Clin Oncol"},{"issue":"17","key":"R7","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1056\/NEJMoa2208375","article-title":"Effect of colonoscopy screening on risks of colorectal cancer and related death","volume":"387","author":"Bretthauer","journal-title":"N Engl J Med"},{"issue":"3","key":"R8","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.cgh.2023.07.021","article-title":"Endoscopic removal of premalignant lesions reduces long-term colorectal cancer risk: results from the Japan Polyp Study","volume":"22","author":"Sano","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"9","key":"R9","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.14309\/ajg.0000000000002972","article-title":"Quality indicators for colonoscopy","volume":"119","author":"Rex","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"R10","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1055\/s-0043-103411","article-title":"Performance measures for lower gastrointestinal endoscopy: a European Society of Gastrointestinal Endoscopy (ESGE) Quality Improvement Initiative","volume":"49","author":"Kaminski","journal-title":"Endoscopy"},{"issue":"2","key":"R11","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1055\/s-0032-1326186","article-title":"Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) guideline","volume":"45","author":"Hassan","journal-title":"Endoscopy"},{"issue":"11","key":"R12","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1038\/ajg.2014.232","article-title":"What level of bowel prep quality requires early repeat colonoscopy: systematic review and meta-analysis of the impact of preparation quality on adenoma detection rate","volume":"109","author":"Clark","journal-title":"Am J Gastroenterol"},{"issue":"6","key":"R13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154149","article-title":"Meta-analysis of the effect of bowel preparation on adenoma detection: early adenomas affected stronger than advanced adenomas","volume":"11","author":"Sulz","journal-title":"PLoS One"},{"issue":"1","key":"R14","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-019-1019-8","article-title":"The effect of quality of segmental bowel preparation on adenoma detection rate","volume":"19","author":"Guo","journal-title":"BMC Gastroenterol"},{"issue":"6","key":"R15","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.12669\/pjms.35.6.1031","article-title":"Impact of bowel preparation on caecal intubation time during colonoscopy","volume":"35","author":"Alvi","journal-title":"Pak J Med Sci"},{"issue":"10","key":"R16","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.14309\/ajg.0000000000002880","article-title":"Impact of bowel preparation quality on colonoscopy findings and colorectal cancer deaths in a nation-wide colorectal cancer screening program","volume":"119","author":"Zessner-Spitzenberg","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"R17","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1053\/j.gastro.2015.04.004","article-title":"Split-dose preparations are superior to day-before bowel cleansing regimens: a meta-analysis","volume":"149","author":"Martel","journal-title":"Gastroenterology"},{"issue":"49","key":"R18","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000023541","article-title":"Low-residue versus clear liquid diet before colonoscopy: an updated meta-analysis of randomized, controlled trials","volume":"99","author":"Chen","journal-title":"Medicine (Baltimore)"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1029493","article-title":"Prepackaged formula low-residue diet vs. self-prepared low-residue diet before colonoscopy: a multicenter randomized controlled trial","volume":"10","author":"Pan","journal-title":"Front Med (Lausanne)"},{"issue":"5","key":"R20","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1038\/ajg.2011.75","article-title":"Development and validation of a novel patient educational booklet to enhance colonoscopy preparation","volume":"106","author":"Spiegel","journal-title":"Am J Gastroenterol"},{"issue":"4","key":"R21","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1016\/j.gie.2012.05.026","article-title":"Impact of patient education with cartoon visual aids on the quality of bowel preparation for colonoscopy","volume":"76","author":"Tae","journal-title":"Gastrointest Endosc"},{"issue":"3","key":"R22","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/j.gie.2018.08.014","article-title":"Improving the quality and acceptance of colonoscopy preparation by reinforced patient education with short message service: results from a randomized, multicenter study (PERICLES-II)","volume":"89","author":"Walter","journal-title":"Gastrointest Endosc"},{"issue":"3","key":"R23","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.cgh.2015.09.038","article-title":"Delivery of instructions via mobile social media app increases quality of bowel preparation","volume":"14","author":"Kang","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"4","key":"R24","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1111\/jan.14295","article-title":"Improving the quality of bowel preparation through an app for inpatients undergoing colonoscopy: a randomized controlled trial","volume":"76","author":"Guo","journal-title":"J Adv Nurs"},{"issue":"2","key":"R25","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.cgh.2020.03.051","article-title":"Smartphone application to reinforce education increases high-quality preparation for colorectal cancer screening colonoscopies in a randomized trial","volume":"19","author":"Walter","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"12","key":"R26","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1111\/den.14827","article-title":"Smartphone application for artificial intelligence-based evaluation of stool state during bowel preparation before colonoscopy","volume":"36","author":"Inaba","journal-title":"Dig Endosc"},{"issue":"3 Pt 2","key":"R27","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.gie.2008.05.057","article-title":"The Boston bowel preparation scale: a valid and reliable instrument for colonoscopy-oriented research","volume":"69","author":"Lai","journal-title":"Gastrointest Endosc"},{"key":"R28","volume":"94","author":"Aronchick","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"R29","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/den.14914","article-title":"Optimal bowel preparation for colonoscopy","volume":"37","author":"Tamai","journal-title":"Dig Endosc"},{"issue":"9","key":"R30","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.14309\/ajg.0000000000001900","article-title":"A novel convolutional neural network model as an alternative approach to bowel preparation evaluation before colonoscopy in the COVID-19 era: a multicenter, single-blinded, randomized study","volume":"117","author":"Lu","journal-title":"Am J Gastroenterol"},{"issue":"1","key":"R31","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-023-00786-y","article-title":"Improving bowel preparation for colonoscopy with a smartphone application driven by artificial intelligence","volume":"6","author":"Zhu","journal-title":"NPJ Digit Med"},{"key":"R32","unstructured":"Information and communications in Japan: white paper [Report in Japanese]. Ministry of Internal Affairs and Communications (MIC); 2020. URL: https:\/\/www.soumu.go.jp\/johotsusintokei\/whitepaper\/ja\/r02\/pdf\/index.html [Accessed 26-05-2026]"},{"key":"R33","unstructured":"Survey on trends in communications usage 2024 [Report in Japanese]. Ministry of Internal Affairs and Communications (MIC); 2025. URL: https:\/\/www.soumu.go.jp\/johotsusintokei\/statistics\/data\/250530_1.pdf [Accessed 24-07-2026]"},{"key":"R34","unstructured":"Editage. URL: https:\/\/www.editage.com\/ [Accessed 24-07-2026]"}],"container-title":["JMIR mHealth and uHealth"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T18:12:32Z","timestamp":1788286352000},"score":1,"resource":{"primary":{"URL":"https:\/\/mhealth.jmir.org\/2026\/1\/e91274"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,1]]},"references-count":34,"URL":"https:\/\/doi.org\/10.2196\/91274","relation":{},"ISSN":["2291-5222"],"issn-type":[{"value":"2291-5222","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,1]]},"article-number":"v14i1e91274"}}