{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:45:30Z","timestamp":1791920730919,"version":"4.3.4"},"reference-count":20,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Res Protoc"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cochlear implantation (CI) is a highly effective intervention for adults with severe-to-profound hearing loss, yet uptake across the United Kingdom remains low despite clear National Institute for Health and Care Excellence (NICE 2019) guidance and well-established clinical benefits. The original Cochlear Implant Referral Criteria Audit (CIRCA-1) identified marked inequities in access to CIs in 2022, with lower referral rates among older adults, males, and individuals from socioeconomically deprived areas, alongside individuals from minority ethnic backgrounds being less likely to be informed of their eligibility for referral. Since then, national awareness initiatives and the expansion of the existing local \u201cCI Champions\u201d scheme have aimed to address these inequities, improve awareness of CI candidacy, and improve the quality of discussions with patients about options for CI referral. This repeat assessment aims to assess the success of these interventions to identify improvements in access to CIs as well as persisting barriers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>CIRCA-2 is a national, multicenter, retrospective observational audit designed to re-evaluate adult CI referral pathways and measure progress since the first audit cycle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study will include adults assessed in secondary-care ear, nose, throat, and audiology departments between July and December 2025 whose audiometric thresholds meet NICE TA566 criteria. Participating centers will identify eligible patients using the British Cochlear Implant Group Crystal Report within Auditbase, and anonymized demographic, audiometric, and service-level data will be extracted. The primary outcomes are the proportions of patients meeting NICE TA566 criteria who were informed of their eligibility and referred for CI assessment, with comparisons made to CIRCA-1 data. Secondary analyses will examine adherence to national standards and predictors of discussion and referral using multivariable modeling. In addition, the study will assess the number of patients within criteria for the Comparing Cochlear Implants With Hearing Aids in Adults (COACH) trial and those meeting CI criteria in one ear only.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Retrospective data for the period July 1 to December 31, 2025, were collected between January and March 2026. Eighty-three sites submitted data relating to 15,060 patients. Data analysis is projected to be complete by October 2026, with publication of final results expected in early 2027.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>By quantifying change over time, CIRCA-2 will provide an updated national picture of CI referral practice, highlight any persisting barriers, and inform future strategies to promote equitable access to CIs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/94888","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:00:06Z","timestamp":1789488006000},"page":"e94888-e94888","source":"Crossref","is-referenced-by-count":0,"title":["Cochlear Implant Referrals in Adults With Severe-to-Profound Hearing Loss in the United Kingdom (CIRCA-2): Protocol for a Repeat National Multicenter Retrospective Observational Study"],"prefix":"10.2196","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1925-6586","authenticated-orcid":false,"given":"Alexander Scott","family":"North","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0431-4491","authenticated-orcid":false,"given":"Chloe","family":"Swords","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5241-4876","authenticated-orcid":false,"given":"Petrina","family":"Checkland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9686-592X","authenticated-orcid":false,"given":"Jessica","family":"Daniels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1314-8904","authenticated-orcid":false,"given":"Oliver George","family":"Denton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9160-5800","authenticated-orcid":false,"given":"Amir","family":"Habeeb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0872-0577","authenticated-orcid":false,"given":"Kim Hui","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3875-0881","authenticated-orcid":false,"given":"Isaac","family":"Jarratt-Barnham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9323-3107","authenticated-orcid":false,"given":"Amar","family":"Rajgor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7534-5183","authenticated-orcid":false,"given":"Bhavesh Vijay","family":"Tailor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2134-3814","authenticated-orcid":false,"given":"Jeremy","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3065-0269","authenticated-orcid":false,"given":"Jameel","family":"Muzaffar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,10,13]]},"reference":[{"key":"R1","unstructured":"World report on hearing. World Health Organization. URL: https:\/\/www.who.int\/teams\/noncommunicable-diseases\/sensory-functions-disability-and-rehabilitation\/highlighting-priorities-for-ear-and-hearing-care [Accessed 19-07-2026]"},{"issue":"10452","key":"R2","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/S0140-6736(24)01296-0","article-title":"Dementia prevention, intervention, and care: 2024 report of the Lancet Standing Commission","volume":"404","author":"Livingston","journal-title":"Lancet"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1177\/2331216519887614","article-title":"Hearing in adults: a digital reprint of the main report from the MRC National Study of Hearing","volume":"23","author":"Akeroyd","journal-title":"Trends Hear"},{"key":"R4","unstructured":"Prevalence of deafness and hearing loss. RNID (Royal National Institute for Deaf People). URL: https:\/\/rnid.org.uk\/what-we-do\/data-and-evidence\/deafness-and-hearing-loss-prevalence [Accessed 19-07-2026]"},{"issue":"2","key":"R5","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1159\/000508433","article-title":"Systematic review of quality of life assessments after cochlear implantation in older adults","volume":"26","author":"Andries","journal-title":"Audiol Neurootol"},{"issue":"44","key":"R6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/hta13440","article-title":"The effectiveness and cost-effectiveness of cochlear implants for severe to profound deafness in children and adults: a systematic review and economic model","volume":"13","author":"Bond","journal-title":"Health Technol Assess"},{"issue":"9","key":"R7","doi-asserted-by":"publisher","first-page":"4455","DOI":"10.1007\/s00405-024-08591-3","article-title":"Cochlear implant cost analysis in adults: a European narrative review","volume":"281","author":"Gatto","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R8","unstructured":"Cullington H . BCIG annual UK data collection. British Cochlear Implant Group; 2022. URL: https:\/\/www.bcig.org.uk\/_userfiles\/pages\/files\/audit\/27922bcigcidata.pdf [Accessed 03-10-2026]"},{"issue":"Suppl 1","key":"R9","doi-asserted-by":"publisher","first-page":"S32","DOI":"10.1179\/1467010013Z.00000000077","article-title":"Cochlear implants in the United Kingdom: awareness and utilization","volume":"14 Suppl 1","author":"Raine","journal-title":"Cochlear Implants Int"},{"issue":"2","key":"R10","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1097\/AUD.0000000000000762","article-title":"Barriers and facilitators to cochlear implant uptake in Australia and the United Kingdom","volume":"41","author":"Bierbaum","journal-title":"Ear Hear"},{"issue":"Suppl 1","key":"R11","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.1179\/1467010013z.00000000076","article-title":"Cochlear implantation in the world\u2019s largest medical device market: utilization and awareness of cochlear implants in the United States","volume":"14","author":"Sorkin","journal-title":"Cochlear Implants Int"},{"issue":"1","key":"R12","doi-asserted-by":"publisher","DOI":"10.3390\/audiolres16010019","article-title":"Trends in adult cochlear implant access and uptake across ten years of reported data","volume":"16","author":"D\u2019Haese","journal-title":"Audiol Res"},{"issue":"4","key":"R13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1004296","article-title":"Socioeconomic and ethnic disparities associated with access to cochlear implantation for severe-to-profound hearing loss: a multicentre observational study of UK adults","volume":"21","author":"Swords","journal-title":"PLoS Med"},{"key":"R14","unstructured":"Cochlear implants for children and adults with severe to profound deafness. National Institute for Health and Care Excellence (NICE); 2019. URL: https:\/\/www.nice.org.uk\/guidance\/ta566\/resources\/cochlear-implants-for-children-and-adults-with-severe-to-profound-deafness-pdf-82607085698245 [Accessed 22-09-2026]"},{"key":"R15","unstructured":"Gregory H . Comparing cochlear implants with hearing aids in adults with severe hearing loss. ISRCTN Registry. URL: https:\/\/www.isrctn.com\/ISRCTN15352106 [Accessed 22-09-2026]"},{"key":"R16","unstructured":"INTEGRATE. URL: https:\/\/entintegrate.co.uk [Accessed 20-07-2026]"},{"key":"R17","unstructured":"What approvals and amendments do I need? NHS Health Research Authority. URL: https:\/\/www.hra.nhs.uk\/approvals-amendments\/what-approvals-do-i-need [Accessed 16-08-2026]"},{"key":"R18","unstructured":"UK policy framework for health and social care research. NHS Health Research Authority. 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