{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:43:50Z","timestamp":1785545030030,"version":"3.56.0"},"reference-count":47,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Hum Factors"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Opioids account for 76% of drug overdose deaths in the United States, with nearly 80,000 opioid overdose deaths annually. The risk of overdose is dynamic and influenced by rapidly changing behaviors and contexts that are not well captured by retrospective or infrequent assessments. Ecological momentary assessment (EMA) allows repeated near real-time reporting of behaviors and experiences in natural settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study evaluated the feasibility and acceptability of smartphone-based EMA among people who use opioids to monitor opioid use, overdose experiences, and naloxone access.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were recruited through the New Haven Syringe Services Program in New Haven, Connecticut, and completed fixed-time, twice-daily EMA prompts for 30 days using a smartphone app. EMA measures assessed behaviors and experiences occurring within the previous 12 hours, including opioid craving, plans to use drugs, opioid use, overdose experiences, and naloxone access. Feasibility was assessed through recruitment, retention, and EMA completion rates, as well as the reporting of drug use-related behaviors. Acceptability was evaluated using exit surveys assessing ease of use, burden, and privacy, as well as qualitative interviews.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 13 screened individuals, 10 were enrolled and completed the baseline assessment. A total of 9 (90%) participants completed EMA and responded to 411 prompts, with an overall compliance rate of a mean of 85.0% (SD 8.7%). Compliance was similar across morning (84.2%, SD 13.1%) and evening (85.8%, SD 11.2%) prompts. Participants reported opioid cravings (274 reports), plans to use illicit drugs (252 reports), and opioid use (411 reports) during the study period. Two participants reported overdose events (5 reports) and were carrying naloxone during each overdose event. Acceptability ratings were high: all participants reported that EMA prompts were easy to understand and private, and most did not find them burdensome. Qualitative feedback further highlighted the ease of use, integration into daily routines, and increased self-awareness, although some participants reported emotional discomfort when reflecting on their substance use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Smartphone-based EMA was feasible and acceptable among people who use opioids recruited through a syringe service program. EMA may support the monitoring of opioid use, overdose experiences, and naloxone access, and it may inform future digital health interventions aimed at reducing harm, including overdose risk, among people who use opioids.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/95655","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:45:31Z","timestamp":1781077531000},"page":"e95655-e95655","source":"Crossref","is-referenced-by-count":0,"title":["Smartphone-Based Ecological Momentary Assessment to Monitor Opioid Use and Overdose Among People Who Use Opioids: Prospective Observational Feasibility Study"],"prefix":"10.2196","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7121-7421","authenticated-orcid":false,"given":"Kamal","family":"Gautam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5590-4133","authenticated-orcid":false,"given":"Kiran","family":"Paudel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7701-9162","authenticated-orcid":false,"given":"Jeffrey A","family":"Wickersham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9350-8230","authenticated-orcid":false,"given":"Antoine","family":"Khati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1879-1945","authenticated-orcid":false,"given":"Anushka","family":"Thapa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3060-5823","authenticated-orcid":false,"given":"Sandesh","family":"Bhusal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-2423","authenticated-orcid":false,"given":"Md Safaet Hossain","family":"Sujan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2462-8797","authenticated-orcid":false,"given":"Sherry","family":"Pagoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0574-0804","authenticated-orcid":false,"given":"Toan","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4340-3101","authenticated-orcid":false,"given":"Roman","family":"Shrestha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"R1","unstructured":"U.S. overdose deaths in 2021 increased half as much as in 2020 \u2013 but are still up 15%. Centers for Disease Control and Prevention, National Center for Health Statistics. URL: https:\/\/www.cdc.gov\/nchs\/pressroom\/releases\/20220511.html?CDC_AAref_Val=https:\/\/www.cdc.gov\/nchs\/pressroom\/nchs_press_releases\/2022\/202205.htm [Accessed 17-06-2026]"},{"issue":"457","key":"R2","first-page":"1","volume":"2022","author":"Spencer","journal-title":"NCHS Data Brief"},{"key":"R3","unstructured":"Garnett MF Mini\u00f1o AM . Drug overdose deaths in the United States, 2003\u20132023. National Center for Health Statistics (NCHS), Centers for Disease Control and Prevention; 2024. URL: https:\/\/www.cdc.gov\/nchs\/products\/databriefs\/db522.htm [Accessed 17-06-2026]"},{"key":"R4","unstructured":"Key substance use and mental health indicators in the United States: results from the 2023 National Survey on Drug Use and Health. Substance Abuse and Mental Health Services Administration (SAMSHA); 2024. URL: https:\/\/www.drugsandalcohol.ie\/41611\/1\/2023-nsduh-annual-national.pdf [Accessed 17-06-2026]"},{"issue":"1","key":"R5","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/s13722-023-00394-x","article-title":"Three decades of research in substance use disorder treatment for syringe services program participants: a scoping review of the literature","volume":"18","author":"Jakubowski","journal-title":"Addict Sci Clin Pract"},{"issue":"1","key":"R6","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-022-00676-8","article-title":"Intersecting substance use treatment and harm reduction services: exploring the characteristics and service needs of a community-based sample of people who use drugs","volume":"19","author":"Krawczyk","journal-title":"Harm Reduct J"},{"issue":"5","key":"R7","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1111\/jcpt.13114","article-title":"Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: current understanding and approaches to management","volume":"45","author":"Pergolizzi Jr","journal-title":"J Clin Pharm Ther"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2025.108427","article-title":"Sleep disruption, stress, and craving during inpatient treatment for opioid use disorder","volume":"170","author":"Bichon","journal-title":"Addict Behav"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1016\/j.josat.2025.209630","article-title":"What are the risk factors of non-fatal overdose among persons who use opioids? A systematic review and meta-analysis","volume":"171","author":"Dunne","journal-title":"J Subst Use Addict Treat"},{"issue":"5","key":"R10","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1007\/s10900-025-01480-8","article-title":"Non-fatal overdose and associated factors among people who use opioids: findings from a cross-sectional study","volume":"50","author":"Sujan","journal-title":"J Community Health"},{"issue":"1","key":"R11","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1080\/24740527.2018.1479842","article-title":"A systematic review of strategies to improve appropriate use of opioids and to reduce opioid use disorder and deaths from prescription opioids","volume":"2","author":"Furlan","journal-title":"Can J Pain"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2018.04.012","article-title":"Exploring opioid use disorder, its impact, and treatment among individuals experiencing homelessness as part of a family","volume":"188","author":"Chatterjee","journal-title":"Drug Alcohol Depend"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2022.04.001","article-title":"Associations of employment status with opioid misuse: evidence from a nationally representative survey in the U.S","volume":"151","author":"Matthews","journal-title":"J Psychiatr Res"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2021.108329","article-title":"Who stays in medication treatment for opioid use disorder? A national study of outpatient specialty treatment settings","volume":"126","author":"Krawczyk","journal-title":"J Subst Abuse Treat"},{"issue":"1","key":"R15","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-021-00539-8","article-title":"Drug use, homelessness and health: responding to the opioid overdose crisis with housing and harm reduction services","volume":"18","author":"Milaney","journal-title":"Harm Reduct J"},{"issue":"1","key":"R16","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1007\/s40429-020-00351-7","article-title":"Ambulatory assessment methods to examine momentary state-based predictors of opioid use behaviors","volume":"8","author":"Burgess-Hull","journal-title":"Curr Addict Rep"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2025.112582","article-title":"Ecological momentary assessment study of same-hour polysubstance use among people who use opioids and additional substances","volume":"269","author":"Lorvick","journal-title":"Drug Alcohol Depend"},{"issue":"3","key":"R18","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1007\/s40429-023-00492-5","article-title":"The use of ecological momentary assessment methods with people receiving medication for opioid use disorder: a systematic review","volume":"10","author":"Alexander","journal-title":"Curr Addict Rep"},{"issue":"4","key":"R19","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1037\/a0017074","article-title":"Ecological momentary assessment (EMA) in studies of substance use","volume":"21","author":"Shiffman","journal-title":"Psychol Assess"},{"issue":"4","key":"R20","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1111\/jrh.12737","article-title":"Substance use disorder treatment and technology access among people who use drugs in rural areas of the United States: a cross-sectional survey","volume":"39","author":"Button","journal-title":"J Rural Health"},{"issue":"2","key":"R21","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1007\/s11469-021-00629-5","article-title":"Potential effects of digital inequality on treatment seeking for opioid use disorder","volume":"21","author":"Garett","journal-title":"Int J Ment Health Addict"},{"issue":"1","key":"R22","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1007\/s13181-024-01040-x","article-title":"Leveraging trauma informed care for digital health intervention development in opioid use disorder","volume":"21","author":"Venkatasubramanian","journal-title":"J Med Toxicol"},{"issue":"4","key":"R23","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1111\/add.14503","article-title":"Compliance with ecological momentary assessment protocols in substance users: a meta-analysis","volume":"114","author":"Jones","journal-title":"Addiction"},{"issue":"3","key":"R24","doi-asserted-by":"publisher","DOI":"10.2196\/50275","article-title":"Investigating best practices for ecological momentary assessment: nationwide factorial experiment","volume":"26","author":"Businelle","journal-title":"J Med Internet Res"},{"issue":"11","key":"R25","doi-asserted-by":"publisher","first-page":"1284","DOI":"10.1097\/01.MLR.0000093487.78664.3C","article-title":"The Patient Health Questionnaire-2: validity of a two-item depression screener","volume":"41","author":"Kroenke","journal-title":"Med Care"},{"issue":"1-3","key":"R26","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1016\/j.jad.2011.06.017","article-title":"How reliable is depression screening in alcohol and drug users? A validation of brief and ultra-brief questionnaires","volume":"134","author":"Delgadillo","journal-title":"J Affect Disord"},{"issue":"10","key":"R27","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1001\/archinte.166.10.1092","article-title":"A brief measure for assessing generalized anxiety disorder: the GAD-7","volume":"166","author":"Spitzer","journal-title":"Arch Intern Med"},{"issue":"8","key":"R28","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1037\/adb0001098","article-title":"Psychometric validation of the Generalized Anxiety Disorder Scale (GAD-7) and Patient Health Questionnaire (PHQ-9) in an inpatient substance use disorder treatment program","volume":"39","author":"Punia","journal-title":"Psychol Addict Behav"},{"issue":"2","key":"R29","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1002\/mpr.168","article-title":"The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI)","volume":"13","author":"Kessler","journal-title":"Int J Methods Psychiatr Res"},{"issue":"4","key":"R30","doi-asserted-by":"publisher","DOI":"10.2196\/36043","article-title":"A 3-item measure of digital health care literacy: development and validation study","volume":"6","author":"Nelson","journal-title":"JMIR Form Res"},{"issue":"3","key":"R31","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1207\/S15324796ABM2403_09","article-title":"Capturing momentary, self-report data: a proposal for reporting guidelines","volume":"24","author":"Stone","journal-title":"Ann Behav Med"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsat.2017.01.007","article-title":"Race\/ethnicity, education, and age are associated with engagement in ecological momentary assessment text messaging among substance-using MSM in San Francisco","volume":"75","author":"Turner","journal-title":"J Subst Abuse Treat"},{"issue":"10","key":"R33","doi-asserted-by":"publisher","first-page":"2231","DOI":"10.1007\/s10461-015-1272-y","article-title":"Using ecological momentary assessment (EMA) to study sex events among very high-risk men who have sex with men (MSM)","volume":"20","author":"Wray","journal-title":"AIDS Behav"},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108167","article-title":"Ecological momentary assessment of daily drug use and harm reduction service utilization among people who inject drugs in non-urban areas: a concurrent mixed-method feasibility study","volume":"214","author":"Biello","journal-title":"Drug Alcohol Depend"},{"issue":"2","key":"R35","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1191\/1478088706qp063oa","article-title":"Using thematic analysis in psychology","volume":"3","author":"Braun","journal-title":"Qual Res Psychol"},{"issue":"3","key":"R36","doi-asserted-by":"publisher","first-page":"324","DOI":"10.4103\/2249-4863.161306","article-title":"Validity, reliability, and generalizability in qualitative research","volume":"4","author":"Leung","journal-title":"J Family Med Prim Care"},{"issue":"5","key":"R37","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1080\/00952990.2018.1454933","article-title":"Using ecological momentary assessment to examine the relationship between craving and affect with opioid use in a clinical trial of clonidine as an adjunct medication to buprenorphine treatment","volume":"44","author":"Kowalczyk","journal-title":"Am J Drug Alcohol Abuse"},{"issue":"7","key":"R38","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-069523","article-title":"Compliance with ecological momentary assessment programmes in the elderly: a systematic review and meta-analysis","volume":"13","author":"Yao","journal-title":"BMJ Open"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1016\/j.invent.2024.100784","article-title":"Predictors of participant compliance with ecological momentary assessment among individuals with chronic pain who are using cannabis and opioids","volume":"38","author":"Joo","journal-title":"Internet Interv"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1016\/j.josat.2025.209685","article-title":"A longitudinal observational study with ecological momentary assessment and deep learning to predict non-prescribed opioid use, treatment retention, and medication nonadherence among persons receiving medication treatment for opioid use disorder","volume":"173","author":"Heinz","journal-title":"J Subst Use Addict Treat"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1016\/j.invent.2021.100460","article-title":"Feasibility and acceptability of using smartphone-based EMA to assess patterns of prescription opioid and medical cannabis use among individuals with chronic pain","volume":"26","author":"Anderson Goodell","journal-title":"Internet Interv"},{"issue":"3","key":"R42","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1177\/00220426241231723","article-title":"A feasibility and acceptability study using ecological momentary assessment to evaluate drug use patterns among midwestern people who use drugs","volume":"55","author":"Tyler","journal-title":"J Drug Issues"},{"issue":"7","key":"R43","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1080\/10826084.2016.1264969","article-title":"Potential risks of ecological momentary assessment among persons who inject drugs","volume":"52","author":"Roth","journal-title":"Subst Use Misuse"},{"key":"R44","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2016.05.014","article-title":"Ethical considerations and potential threats to validity for three methods commonly used to collect geographic information in studies among people who use drugs","volume":"61","author":"Rudolph","journal-title":"Addict Behav"},{"issue":"9","key":"R45","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e20084","article-title":"Feedback based on experience sampling data: examples of current approaches and considerations for future research","volume":"9","author":"Bartels","journal-title":"Heliyon"},{"issue":"5","key":"R46","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.1111\/add.15687","article-title":"Technology-mediated just-in-time adaptive interventions (JITAIs) to reduce harmful substance use: a systematic review","volume":"117","author":"Perski","journal-title":"Addiction"},{"issue":"6","key":"R47","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1016\/j.jadohealth.2025.07.027","article-title":"Just-in-time adaptive interventions for adolescent and young adult substance use: a systematic review","volume":"77","author":"Koike","journal-title":"J Adolesc Health"}],"container-title":["JMIR Human Factors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/humanfactors.jmir.org\/2026\/1\/e95655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:23:19Z","timestamp":1785536599000},"score":1,"resource":{"primary":{"URL":"https:\/\/humanfactors.jmir.org\/2026\/1\/e95655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":47,"URL":"https:\/\/doi.org\/10.2196\/95655","relation":{},"ISSN":["2292-9495"],"issn-type":[{"value":"2292-9495","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,29]]},"article-number":"v13i457e95655"}}