{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:57:27Z","timestamp":1790834247756,"version":"4.1.0"},"reference-count":35,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Infodemiology"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec sec-type=\"background\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with seizure clusters and their families often use YouTube videos as resources for information about the illness and how to use concomitant rescue medications; however, many videos include misinformation or incorrect information that could potentially cause harm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"objective\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to examine YouTube videos intended as educational and instructional resources for seizure clusters and treatment options posted since the approval of intranasal benzodiazepine rescue medications in 2019 and to assess their accuracy and quality using a 3-item rating scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"methods\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We searched YouTube for 10 specific terms related to seizure clusters and treatment options and analyzed videos from the first 20 results for each to mimic internet user behavior when choosing results with search engines. Videos were rated on 3 criteria: accurate seizure cluster definition, appropriate US Food and Drug Administration (FDA)\u2013approved treatment recommendation, and correct visual demonstration of rescue medication use. A single author rated the videos based on the presence of specific subcriteria of all 3 primary criteria in each video. Score assignment was based on the number of present subcriteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"results\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Seizure clusters and trade names generated the highest number of videos meeting criteria; other search terms, including nonproprietary names, garnered &lt;8 videos each. Only 19.5% (n=39) of the 200 collected videos provided accurate descriptions of seizure clusters, while 61.0% (n=122) offered no definition, 37.0% (n=74) recommended at least 1 FDA-approved rescue medication, and 37.5% (n=75) offered no rescue therapy at all; 26.5% (n=53) provided a full demonstration of rescue medicine, while 62.5% (n=125) did not. Only 4.5% (n=9) of videos included all subcriteria of the 3 primary criteria. Search results for specific trade names yielded more results, while less specific terminology returned unrelated or unhelpful videos.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec sec-type=\"conclusions\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Accurate YouTube videos of seizure cluster management are limited and represent a knowledge gap that should be addressed to avoid patient harm. To facilitate better navigation of educational and instructional resources, clinicians should have a ready list of videos available to give to patients or provide a list of search terms that are known to produce accurate results to facilitate better searches. Reputable health care sources could also produce brief, helpful videos of each rescue therapy with search terms that direct patients to their content.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2196\/98768","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T08:50:05Z","timestamp":1788166205000},"page":"e98768-e98768","source":"Crossref","is-referenced-by-count":0,"title":["YouTube Videos as Educational Resources for Seizure Clusters and Treatment Options: Cross-Sectional Observational Study"],"prefix":"10.2196","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4720-5865","authenticated-orcid":false,"given":"Taylor S","family":"Elliott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6847-3387","authenticated-orcid":false,"given":"Andrew J","family":"Gienapp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4735-3431","authenticated-orcid":false,"given":"James W","family":"Wheless","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1010","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2020.107391","article-title":"Seizure clusters, rescue treatments, seizure action plans: unmet needs and emerging formulations","volume":"112","author":"Gidal","journal-title":"Epilepsy Behav"},{"issue":"26","key":"R2","doi-asserted-by":"publisher","first-page":"1869","DOI":"10.1056\/NEJM199806253382602","article-title":"A comparison of rectal diazepam gel and placebo for acute repetitive seizures","volume":"338","author":"Dreifuss","journal-title":"N Engl J Med"},{"issue":"5","key":"R3","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1212\/wnl.51.5.1274","article-title":"Treating repetitive seizures with a rectal diazepam formulation: a randomized study","volume":"51","author":"Cereghino","journal-title":"Neurology"},{"issue":"1 Suppl","key":"R4","doi-asserted-by":"publisher","first-page":"S36","DOI":"10.1177\/08830738020170010501","article-title":"Status epilepticus and acute serial seizures in children","volume":"17","author":"Mitchell","journal-title":"J Child Neurol"},{"issue":"1","key":"R5","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.yebeh.2005.08.018","article-title":"Seizure clustering","volume":"8","author":"Haut","journal-title":"Epilepsy Behav"},{"issue":"2","key":"R6","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1046\/j.1528-1157.2001.15100.x","article-title":"Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring","volume":"42","author":"Yen","journal-title":"Epilepsia"},{"issue":"7","key":"R7","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1046\/j.1528-1157.2002.26401.x","article-title":"Seizure clustering during epilepsy monitoring","volume":"43","author":"Haut","journal-title":"Epilepsia"},{"issue":"6","key":"R8","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1212\/01.wnl.0000053748.83309.28","article-title":"Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoring","volume":"60","author":"Rose","journal-title":"Neurology"},{"issue":"8","key":"R9","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1212\/01.wnl.0000180685.84547.7f","article-title":"Identifying seizure clusters in patients with epilepsy","volume":"65","author":"Haut","journal-title":"Neurology"},{"issue":"6","key":"R10","doi-asserted-by":"publisher","first-page":"495","DOI":"10.4065\/84.6.495","article-title":"Safety of long-term video-electroencephalographic monitoring for evaluation of epilepsy","volume":"84","author":"Noe","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"R11","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.clinph.2011.08.011","article-title":"Seizure clusters and adverse events during pre-surgical video-EEG monitoring with a slow anti-epileptic drug (AED) taper","volume":"123","author":"Di Gennaro","journal-title":"Clin Neurophysiol"},{"issue":"2-3","key":"R12","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.eplepsyres.2009.08.006","article-title":"Prevalence of acute repetitive seizures (ARS) in the United Kingdom","volume":"87","author":"Martinez","journal-title":"Epilepsy Res"},{"issue":"2","key":"R13","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1097\/WCO.0000000000000177","article-title":"Seizure clusters: characteristics and treatment","volume":"28","author":"Haut","journal-title":"Curr Opin Neurol"},{"issue":"6","key":"R14","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1097\/NRL.0000000000000140","article-title":"Burden of seizure clusters on patients with epilepsy and caregivers: survey of patient, caregiver, and clinician perspectives","volume":"22","author":"Penovich","journal-title":"Neurologist"},{"key":"R15","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.05.013","article-title":"Seizure cluster: definition, prevalence, consequences, and management","volume":"68","author":"Jafarpour","journal-title":"Seizure"},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2021.107836","article-title":"Preferred practices for rescue treatment of seizure clusters: a consensus-driven, multi-stakeholder approach","volume":"117","author":"Buchhalter","journal-title":"Epilepsy Behav"},{"issue":"4","key":"R17","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1002\/epd2.20243","article-title":"Outpatient management of prolonged seizures and seizure clusters to prevent progression to a higher-level emergency: consensus recommendations of an expert working group","volume":"26","author":"Pina-Garza","journal-title":"Epileptic Disord"},{"issue":"5","key":"R18","doi-asserted-by":"publisher","DOI":"10.3390\/jcm15051847","article-title":"Seizure clusters: current concepts in definition and treatment","volume":"15","author":"Bassani","journal-title":"J Clin Med"},{"issue":"6","key":"R19","doi-asserted-by":"publisher","first-page":"1398","DOI":"10.1111\/epi.17241","article-title":"International League Against Epilepsy classification and definition of epilepsy syndromes with onset in childhood: position paper by the ILAE Task Force on Nosology and Definitions","volume":"63","author":"Specchio","journal-title":"Epilepsia"},{"issue":"6","key":"R20","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1111\/epi.17237","article-title":"Methodology for classification and definition of epilepsy syndromes with list of syndromes: report of the ILAE Task Force on Nosology and definitions","volume":"63","author":"Wirrell","journal-title":"Epilepsia"},{"issue":"5","key":"R21","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s40120-023-00515-3","article-title":"Treatment of seizure clusters in epilepsy: a narrative review on rescue therapies","volume":"12","author":"Becker","journal-title":"Neurol Ther"},{"issue":"1","key":"R22","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s40272-023-00601-x","article-title":"Practical questions about rescue medications for acute treatment of seizure clusters in children and adolescents with epilepsy in the USA: expanding treatment options to address unmet needs","volume":"26","author":"Wheless","journal-title":"Paediatr Drugs"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1016\/j.yebeh.2013.11.020","article-title":"Why do people Google epilepsy? An infodemiological study of online behavior for epilepsy-related search terms","volume":"31","author":"Brigo","journal-title":"Epilepsy Behav"},{"issue":"Pt A","key":"R24","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.yebeh.2017.04.033","article-title":"Social media in epilepsy: a quantitative and qualitative analysis","volume":"71","author":"Meng","journal-title":"Epilepsy Behav"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1002\/epd2.70309","article-title":"Disinformation and misinformation in epilepsy: an analysis of multiplatform short-form social media video content","author":"St-Pierre","journal-title":"Epileptic Disord"},{"issue":"7","key":"R26","doi-asserted-by":"publisher","first-page":"804","DOI":"10.1177\/0883073811402345","article-title":"YouTube videos as a teaching tool and patient resource for infantile spasms","volume":"26","author":"Fat","journal-title":"J Child Neurol"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2026.02.002","article-title":"Quality and safety of YouTube videos on epilepsy-specific exercises: a systematic analysis using a novel evaluation tool","volume":"136","author":"Gonulal","journal-title":"Seizure"},{"issue":"1","key":"R28","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.yebeh.2013.01.017","article-title":"The presentation of seizures and epilepsy in YouTube videos","volume":"27","author":"Wong","journal-title":"Epilepsy Behav"},{"issue":"1","key":"R29","doi-asserted-by":"publisher","DOI":"10.1186\/s12909-022-03446-z","article-title":"Is YouTube a reliable source of health-related information? a systematic review","volume":"22","author":"Osman","journal-title":"BMC Med Educ"},{"issue":"8","key":"R30","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.43916","article-title":"Epilepsy videos on YouTube: a cross-sectional observational study","volume":"15","author":"Bhoot","journal-title":"Cureus"},{"issue":"7","key":"R31","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1055\/s-0033-1353142","article-title":"YouTube as a source of information for children with paroxysmal episodes","volume":"225","author":"Borusiak","journal-title":"Klin Padiatr"},{"key":"R32","unstructured":"Dean B . How people use Google search (new user behavior study). Backlinko. Apr 14, 2025. URL: https:\/\/backlinko.com\/google-user-behavior [Accessed 14-09-2026]"},{"key":"R33","unstructured":"Dean B . 74 important SEO statistics. Backlinko. Jan 16, 2026. URL: https:\/\/backlinko.com\/seo-stats [Accessed 14-09-2026]"},{"key":"R34","unstructured":"Fishkin R . The state of searcher behavior revealed through 23 remarkable statistics. Moz. Mar 14, 2017. URL: https:\/\/moz.com\/blog\/state-of-searcher-behavior-revealed [Accessed 14-09-2026]"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2026.1802156","article-title":"Functional neurological disorder on YouTube: how reliable is the information?","volume":"14","author":"Alpua","journal-title":"Front Public Health"}],"container-title":["JMIR Infodemiology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:05:54Z","timestamp":1790831154000},"score":1,"resource":{"primary":{"URL":"https:\/\/infodemiology.jmir.org\/2026\/1\/e98768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":35,"URL":"https:\/\/doi.org\/10.2196\/98768","relation":{},"ISSN":["2564-1891"],"issn-type":[{"value":"2564-1891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"article-number":"v6i26e98768"}}