{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T01:48:17Z","timestamp":1775094497279,"version":"3.50.1"},"reference-count":52,"publisher":"JMIR Publications Inc.","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMIR Med Inform"],"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n Artificial intelligence (AI) has shown exponential growth and advancements, revolutionizing various fields, including health care. However, domain adaptation remains a significant challenge, as machine learning (ML) models often need to be applied across different health care settings with varying patient demographics and practices. This issue is critical for ensuring effective and equitable AI deployment. Cardiovascular diseases (CVDs), the leading cause of global mortality with 17.9 million annual deaths, encompass conditions like coronary heart disease and hypertension. The increasing availability of medical data, coupled with AI advancements, offers new opportunities for early detection and intervention in cardiovascular events, leveraging AI\u2019s capacity to analyze complex datasets and uncover critical patterns.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n This review aims to examine AI methodologies combined with medical data to advance the intelligent monitoring and detection of CVDs, identifying areas for further research to enhance patient outcomes and support early interventions.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This review follows the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology to ensure a rigorous and transparent literature review process. This structured approach facilitated a comprehensive overview of the current state of research in this field.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Through the methodology used, 64 documents were retrieved, of which 40 documents met the inclusion criteria. The reviewed papers demonstrate advancements in AI and ML for CVD detection, classification, prediction, diagnosis, and patient monitoring. Techniques such as ensemble learning, deep neural networks, and feature selection improve prediction accuracy over traditional methods. ML models predict cardiovascular events and risks, with applications in monitoring via wearable technology. The integration of AI in health care supports early detection, personalized treatment, and risk assessment, possibly improving the management of CVDs.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The study concludes that AI and ML techniques can improve the accuracy of CVD classification, prediction, diagnosis, and monitoring. The integration of multiple data sources and noninvasive methods supports continuous monitoring and early detection. 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