{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:51:04Z","timestamp":1787755864536,"version":"build-2784847793"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","funder":[{"DOI":"10.13039\/100020365","name":"Centers for Disease Control and Prevention Foundation","doi-asserted-by":"crossref","award":["grant\/cooperative agreement number 1 NU50CK000585-01-00"],"award-info":[{"award-number":["grant\/cooperative agreement number 1 NU50CK000585-01-00"]}],"id":[{"id":"10.13039\/100020365","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["CJASN"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      For some patients, peritoneal dialysis (PD) has several advantages over center-based hemodialysis. PD-related infections such as peritonitis and PD catheter exit site and tunnel infections are a significant source of morbidity. Peritonitis leads to increased mortality, and it is the leading cause of transfer off PD. Infection prevention practices may vary widely across dialysis centers, resulting in significant differences in infection rates. To address these issues and improve patient outcomes, the American Society of Nephrology facilitated the development of core interventions aimed at reducing PD-related infections across US dialysis facilities. The core interventions focus on six key strategies: (\n                      <jats:italic toggle=\"yes\">1<\/jats:italic>\n                      ) regular surveillance and feedback on infection rates, (\n                      <jats:italic toggle=\"yes\">2<\/jats:italic>\n                      ) standardized staff training and competency assessments, (\n                      <jats:italic toggle=\"yes\">3<\/jats:italic>\n                      ) standardized patient and care partner\/caregiver education, (\n                      <jats:italic toggle=\"yes\">4<\/jats:italic>\n                      ) routine infection prevention assessments, (\n                      <jats:italic toggle=\"yes\">5<\/jats:italic>\n                      ) antimicrobial prophylaxis for PD catheter exit sites, and (\n                      <jats:italic toggle=\"yes\">6<\/jats:italic>\n                      ) prophylactic antimicrobials for certain procedures and events. These strategies, on the basis of evidence and international guidelines, emphasize consistency in implementation and monitoring at the facility level. The workgroup followed an iterative process, incorporating expert review and feedback to inform and refine these interventions. Effective implementation requires coordinated efforts among dialysis teams, patients, and support networks, with ongoing evaluation through surveillance and quality improvement initiatives. Although the interventions are grounded in current evidence, additional research is necessary to refine practices and address emerging challenges. The goal is to reduce infection risks, improve the quality of life for patients on PD, and support national efforts to expand home dialysis use.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.0000000976","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T17:03:26Z","timestamp":1764954206000},"page":"1439-1444","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Core Interventions for the Prevention of Peritoneal Dialysis\u2013Related Infections"],"prefix":"10.2215","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0008-7623","authenticated-orcid":false,"given":"Jeffrey","family":"Perl","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Medicine, St. Michael's Hospital Unity Health Toronto, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7526-6837","authenticated-orcid":false,"given":"Isaac","family":"Teitelbaum","sequence":"additional","affiliation":[{"name":"Division of Kidney Diseases and Hypertension, University of Colorado School of Medicine, Aurora, Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bradley A.","family":"Warady","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Children's Mercy Kansas City, Kansas City, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5638-4168","authenticated-orcid":false,"given":"Alicia","family":"Neu","sequence":"additional","affiliation":[{"name":"Johns Hopkins University School of Medicine, Baltimore, 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