{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T07:30:33Z","timestamp":1786433433666,"version":"build-2736575974"},"reference-count":95,"publisher":"Ovid Technologies (Wolters Kluwer Health)","funder":[{"name":"Office of Research and Development","award":["HX0003533"],"award-info":[{"award-number":["HX0003533"]}]},{"name":"Office of Rural Health","award":["04269"],"award-info":[{"award-number":["04269"]}]},{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"crossref","award":["HMC-2023C2-33427"],"award-info":[{"award-number":["HMC-2023C2-33427"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["CJASN"],"abstract":"<jats:p>Hypertension is a major contributor to kidney and cardiovascular morbidity and mortality in CKD, yet achieving BP control remains challenging. Team-based care, particularly involving clinical pharmacists, has demonstrated effectiveness in the management of hypertension with the bulk of the evidence in non-CKD populations. In this article, we review the evidence evaluating pharmacist-led interventions in BP management generally and in CKD. Notably, pharmacist-led interventions that have integrated clinical pharmacists into care teams with medication management capabilities showed the greatest promise for improving BP control. By contrast, studies that implemented models relying on asynchronous recommendations often failed to achieve significant BP reductions. Common barriers to pharmacist-led interventions in CKD include workflow integration, resource constraints, and limited reimbursement pathways despite the evidence indicating high acceptance of pharmacist-led interventions from patients. Additional research is needed to evaluate the effectiveness of pharmacist-led interventions in CKD and to identify sustainable and scalable implementation strategies for pharmacist integration to improve BP control in CKD.<\/jats:p>","DOI":"10.2215\/cjn.0000001139","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T16:00:42Z","timestamp":1780934442000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing Hypertension Control in CKD Through Collaborative Pharmacist Interventions"],"prefix":"10.2215","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1922-0877","authenticated-orcid":false,"given":"Masaaki","family":"Yamada","sequence":"first","affiliation":[{"name":"Center for Access and Delivery Research and Evaluation, Iowa City Veterans Affairs Health Care System, Iowa City, Iowa"},{"name":"Division of Nephrology and Hypertension, Carver College of Medicine, University of Iowa, Iowa City, Iowa"},{"name":"Veterans Health Administration Office of Rural Health, Veterans Rural Health Resource Center, Iowa City Veterans Affairs Health Care System, Iowa City, Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9183-9909","authenticated-orcid":false,"given":"Jennifer","family":"Van Tiem","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6568-8825","authenticated-orcid":false,"given":"Rachel","family":"Hoskins","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Practice and Science, University of Iowa College of Pharmacy, Iowa City, Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6470-9594","authenticated-orcid":false,"given":"Korey","family":"Kennelty","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa"},{"name":"Department of Pharmacy Practice and Science, University of Iowa College of Pharmacy, Iowa City, Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1975-8650","authenticated-orcid":false,"given":"Diana","family":"Jalal","sequence":"additional","affiliation":[{"name":"Center for Access and Delivery Research and Evaluation, Iowa City Veterans Affairs Health Care System, Iowa City, Iowa"},{"name":"Division of Nephrology and Hypertension, Carver College of Medicine, University of Iowa, Iowa City, 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