{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:13:03Z","timestamp":1791943983578,"version":"4.3.4"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Enteric overabsorption of oxalate may lead to hyperoxaluria and subsequent acute oxalate nephritis (AON). AON related to chronic pancreatitis is a rare and poorly described condition precluding early recognition and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting, participants, &amp; measurements<\/jats:title>\n                    <jats:p>We collected the clinical characteristics, treatment, and renal outcome of 12 patients with chronic pancreatitis\u2013associated AON followed in four French renal units.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Before AON, mild to moderate chronic kidney disease was present in all patients, diabetes mellitus in eight (insulin [\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 6]; oral antidiabetic drugs [\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 2]), and known chronic pancreatitis in only eight. At presentation, pancreas imaging showed gland atrophy\/heterogeneity, Wirsung duct dilation, calcification, or pseudocyst. Renal findings consisted of rapidly progressive renal failure with tubulointerstitial profile. Acute modification of glomerular filtration preceded the AON (\n                      <jats:italic toggle=\"yes\">i.e.,<\/jats:italic>\n                      diarrhea and diuretics). Increase in urinary oxalate excretion was found in all tested patients and hypocalcemia in nine (&lt;1.5 mmol\/L in four patients). Renal biopsy showed diffuse crystal deposits, highly suggestive of oxalate crystals, with tubular necrosis and interstitial inflammatory cell infiltrates. Treatment consisted of pancreatic enzyme supplementation, oral calcium intake, and an oxalate-free diet in all patients and renal replacement therapy in five patients. After a median follow-up of 7 months, three of 12 patients reached end-stage renal disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AON is an under-recognized severe crystal-induced renal disease with features of tubulointerstitial nephritis that may occur in patients with a long history of chronic pancreatitis or reveal the pancreatic disease. Extrinsic triggering factors should be prevented.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.00010111","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T11:30:21Z","timestamp":1310124621000},"page":"1895-1902","source":"Crossref","is-referenced-by-count":72,"title":["Oxalate Nephropathy Associated with Chronic Pancreatitis"],"prefix":"10.2215","volume":"6","author":[{"given":"Claire","family":"Cartery","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Faguer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Karras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Cointault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Buscail","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Modesto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ribes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Rostaing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Chauveau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Giraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-16-20230811","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1038\/ki.2009.32","article-title":"The primary hyperoxalurias","volume":"75","author":"Hoppe","year":"2009","journal-title":"Kidney Int"},{"key":"R3-16-20230811","doi-asserted-by":"crossref","first-page":"E3","DOI":"10.1053\/ajkd.2002.33934","article-title":"Enteric hyperoxaluria: A hidden cause of early renal graft failure in two successive transplants: Spontaneous late graft recovery","volume":"40","author":"Cuvelier","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"R4-16-20230811","first-page":"116","article-title":"Acute deterioration of renal function associated with enteric hyperoxaluria","volume":"34","author":"Wharton","year":"1990","journal-title":"Clin Nephrol"},{"key":"R5-16-20230811","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.2215\/CJN.02940608","article-title":"Oxalate nephropathy complicating Roux-en-Y Gastric Bypass: An underrecognized cause of irreversible renal failure","volume":"3","author":"Nasr","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"R6-16-20230811","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1136\/gut.18.7.561","article-title":"Hyperoxaluria correlates with fat malabsorption in patients with sprue","volume":"18","author":"McDonald","year":"1977","journal-title":"Gut"},{"key":"R7-16-20230811","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/00007890-200209150-00020","article-title":"Renal allograft survival in patients with oxalosis","volume":"74","author":"Cibrik","year":"2002","journal-title":"Transplantation"},{"key":"R8-16-20230811","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.1056\/NEJMct0806112","article-title":"Fomepizole for ethylene glycol and methanol poisoning","volume":"360","author":"Brent","year":"2009","journal-title":"N Engl J Med"},{"key":"R9-16-20230811","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.soard.2005.07.002","article-title":"Enteric hyperoxaluria, nephrolithiasis, and oxalate nephropathy: Potentially serious and unappreciated complications of Roux-en-Y gastric bypass","volume":"1","author":"Nelson","year":"2005","journal-title":"Surg Obes Relat Dis"},{"key":"R10-16-20230811","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1093\/ndt\/17.7.1348","article-title":"Crystals from fat. 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