{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:34:38Z","timestamp":1792290878202,"version":"4.4.0"},"reference-count":118,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJASN"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>\n                    Paraproteins are monoclonal Igs that accumulate in blood as a result of abnormal excess production. These circulating proteins cause a diversity of kidney disorders that are increasingly being comanaged by nephrologists. In this review, we discuss paraprotein-related diseases that affect the glomerulus. We provide a broad overview of diseases characterized by nonorganized deposits, such as monoclonal Ig deposition disease (MIDD), proliferative GN with monoclonal Ig deposits (PGNMID), and C3 glomerulopathy, as well as those characterized by organized deposits, such as amyloidosis, immunotactoid glomerulopathy, fibrillary GN, and cryoglobulinemic GN, and rarer disorders, such as monoclonal crystalline glomerulopathies, paraprotein\u2013related thrombotic microangiopathies, and membranous-like glomerulopathy with masked IgG\n                    <jats:italic toggle=\"yes\">\u03ba<\/jats:italic>\n                    deposits. This review will provide the nephrologist with an up to date understanding of these entities and highlight the areas of deficit in evidence and future lines of research.\n                  <\/jats:p>","DOI":"10.2215\/cjn.02980316","type":"journal-article","created":{"date-parts":[[2016,8,15]],"date-time":"2016-08-15T20:23:57Z","timestamp":1471292637000},"page":"2260-2272","source":"Crossref","is-referenced-by-count":60,"title":["Paraprotein\u2013Related Kidney Disease: Glomerular Diseases Associated with Paraproteinemias"],"prefix":"10.2215","volume":"11","author":[{"given":"Shveta S.","family":"Motwani","sequence":"first","affiliation":[{"name":"Division of Renal Medicine, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts;"},{"name":"Adult Survivorship Program, Dana Farber Cancer Institute, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leal","family":"Herlitz","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cleveland Clinic, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Monga","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenar D.","family":"Jhaveri","sequence":"additional","affiliation":[{"name":"Division of Kidney Diseases and Hypertension, Hofstra Northwell School of Medicine, Northwell Health, Great Neck, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert Q.","family":"Lam","sequence":"additional","affiliation":[{"name":"Division of Renal Medicine, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, Massachusetts;"},{"name":"Adult Survivorship Program, Dana Farber Cancer Institute, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the American Society of Nephrology Onco-Nephrology Forum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2016,8,15]]},"reference":[{"key":"B1-20230813","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/0002-9343(78)90522-3","article-title":"Monoclonal gammopathy of undetermined significance. 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