{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:57:19Z","timestamp":1787162239743,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,4]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Heart failure occurs frequently in end-stage renal disease patients. However, there are no prospective, longitudinal follow-up data on its prevalence, severity, and risk factors in long-term peritoneal dialysis (PD) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting, participants, &amp; measurements<\/jats:title>\n                    <jats:p>A prospective observational study was conducted in 220 long-term PD patients followed up for 4 years or until death. Echocardiography was obtained at baseline. Primary study end points were heart failure and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty-six patients had a previous history of heart failure at study entry. The cumulative 4-year survival probability was 37.4% and 64.7% for patients with and without previous heart failure, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.0001). During follow-up, 87 patients (40.9%) developed heart failure, of which 53 were recurrence and 34 were new-onset heart failure. Diabetes, background atherosclerotic vascular disease, systolic hypertension, left ventricular (LV) mass index, systolic dysfunction, and hypoalbuminemia were significant risk factors predicting heart failure in the entire cohort. Diabetes and LV mass and volume index were significant predictors of new-onset heart failure. Systolic hypertension, LV volume index, and hypoalbuminemia were significant predictors of recurrent heart failure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Heart failure is a highly prevalent complication in long-term PD patients and predicts adverse clinical outcomes. More attention should be focused on improving BP and volume control and identifying treatment strategies that effectively lower atherosclerotic burden and reverse LV hypertrophy, remodeling, and systolic dysfunction in PD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.07130810","type":"journal-article","created":{"date-parts":[[2011,1,7]],"date-time":"2011-01-07T00:07:03Z","timestamp":1294358823000},"page":"805-812","source":"Crossref","is-referenced-by-count":52,"title":["Heart Failure in Long-Term Peritoneal Dialysis Patients"],"prefix":"10.2215","volume":"6","author":[{"given":"Angela Yee-Moon","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher Wai-Kei","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iris Hiu-Shuen","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siu-Fai","family":"Lui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John E.","family":"Sanderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20230811","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/ki.1995.132","article-title":"Congestive heart failure in dialysis patients: Prevalence, incidence, prognosis and risk factors","volume":"47","author":"Harnett","year":"1995","journal-title":"Kidney Int"},{"key":"R2-18-20230811","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1681\/ASN.V7102169","article-title":"Early death in dialysis patients: Risk factors and impact on incidence and mortality rates","volume":"7","author":"Soucie","year":"1996","journal-title":"J Am Soc Nephrol"},{"key":"R3-18-20230811","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1097\/01.ASN.0000070071.57901.B3","article-title":"Is a single time point C-reactive protein predictive of outcome in peritoneal dialysis patients?","volume":"14","author":"Wang","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"R4-18-20230811","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1161\/HYPERTENSIONAHA.108.112334","article-title":"Left ventricular filling pressure by Doppler echocardiography in patients with end-stage renal disease","volume":"52","author":"Wang","year":"2008","journal-title":"Hypertension"},{"key":"R5-18-20230811","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0735-1097(97)88335-0","article-title":"Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function","volume":"30","author":"Sohn","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"R6-18-20230811","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0735-1097(97)00344-6","article-title":"Doppler tissue imaging: A noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures","volume":"30","author":"Nagueh","year":"1997","journal-title":"J Am Coll Cardiol"},{"key":"R7-18-20230811","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1177\/089686080302300406","article-title":"Acute effects of high-dose furosemide on residual renal function in CAPD patients","volume":"23","author":"van Olden","year":"2003","journal-title":"Perit Dial Int"},{"key":"R8-18-20230811","doi-asserted-by":"crossref","first-page":"M139","DOI":"10.1097\/00002480-199207000-00004","article-title":"Cross-sectional assessment of weekly urea and creatinine clearances in patients on continuous ambulatory peritoneal dialysis","volume":"38","author":"Nolph","year":"1992","journal-title":"ASAIO J"},{"key":"R9-18-20230811","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1161\/01.CIR.102.15.1788","article-title":"Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study","volume":"102","author":"Ommen","year":"2000","journal-title":"Circulation"},{"key":"R10-18-20230811","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1161\/01.CIR.94.9.2138","article-title":"Assessment of left ventricular filling pressures by Doppler in the presence of atrial fibrillation","volume":"94","author":"Nagueh","year":"1996","journal-title":"Circulation"},{"key":"R11-18-20230811","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1161\/01.CIR.98.16.1644","article-title":"Doppler estimation of left ventricular filling pressure in sinus tachycardia. 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