{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:42:55Z","timestamp":1786372975102,"version":"build-2736575974"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>African Americans (AAs) have four times higher prevalence of ESRD than Caucasians. Therefore, long-term effects of kidney donation are of considerable importance in this patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting, participants, &amp; measurements<\/jats:title>\n                    <jats:p>\n                      GFR was measured by\n                      <jats:sup>125<\/jats:sup>\n                      I-iothalamate clearance, 24-hour urine albumin excretion, and 24-hour BP monitoring in 33 AAs and 11 CAs who donated kidneys for transplantation 5 to 23 years previously.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean GFRs were 76 \u00b1 13 and 78 \u00b1 11 ml\/min per 1.73 m\n                      <jats:sup>2<\/jats:sup>\n                      for AA and CA donors, respectively. Nine percent of the AA donors and none of the CA donors had GFRs below 60 ml\/min per 1.73 m\n                      <jats:sup>2<\/jats:sup>\n                      . AA donors had a tendency for lower prevalence of microalbuminuria compared with CA donors (18.1%\n                      <jats:italic toggle=\"yes\">versus<\/jats:italic>\n                      36.3%) and a tendency for higher prevalence of macroalbuminuria compared with CAs (12.1%\n                      <jats:italic toggle=\"yes\">versus<\/jats:italic>\n                      0.0%). Twenty-four percent of the AAs, and 45% of the CAs were hypertensive with mean daytime BP \u2265135\/85 mmHg. Only 6% of AAs had a decrease in mean nocturnal systolic BP of 10% or more as compared with daytime readings. Older age at time of donation was associated (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.046) with lower GFR values compared with younger ages.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Carefully selected AA kidney donors have well preserved renal function and a low prevalence of hypertension many years after kidney donation. Abnormal albumin excretion and loss of physiologic decrease in nocturnal BP is more prevalent in AA donors than the general AA population. Older age at donation may predict lower GFR after donation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.08240910","type":"journal-article","created":{"date-parts":[[2011,5,5]],"date-time":"2011-05-05T23:41:41Z","timestamp":1304638901000},"page":"1474-1480","source":"Crossref","is-referenced-by-count":7,"title":["Long-Term Effects of Kidney Donation on Renal Function and Blood Pressure in African Americans"],"prefix":"10.2215","volume":"6","author":[{"given":"Milos N.","family":"Budisavljevic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Nietert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusheng","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary J.","family":"Dooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.R.","family":"Rajagopalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-33-20230811","doi-asserted-by":"crossref","first-page":"2915","DOI":"10.1093\/ndt\/gfp295","article-title":"Survival among nocturnal home haemodialysis patients compared to kidney transplant recipients","volume":"24","author":"Pauly","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"R2-33-20230811","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1056\/NEJM199508103330601","article-title":"High survival rates of kidney transplants from spousal and living unrelated donors","volume":"333","author":"Terasaki","year":"1995","journal-title":"N Engl J Med"},{"key":"R3-33-20230811","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1097\/TP.0b013e3181c626e1","article-title":"The altruistic unbalanced paired kidney exchange: Proof of concept and survey of potential donor and recipient attitudes","volume":"89","author":"Ratner","year":"2010","journal-title":"Transplantation"},{"key":"R4-33-20230811","doi-asserted-by":"crossref","first-page":"885","DOI":"10.2215\/CJN.00840306","article-title":"Medical risks in living kidney donors: Absence of proof is not proof of absence","volume":"1","author":"Ommen","year":"2006","journal-title":"Clin. 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