{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T12:18:38Z","timestamp":1793881118668,"version":"4.7.0"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","funder":[{"DOI":"10.13039\/100007299","name":"Harvard Catalyst","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007299","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1 TR001102"],"award-info":[{"award-number":["UL1 TR001102"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007229","name":"Harvard University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007229","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Safra Foundation"},{"DOI":"10.13039\/100007519","name":"Nephcure Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007519","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["CJASN"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>FSGS recurrence after kidney transplantation is a major risk factor for graft loss. However, the natural history, clinical predictors, and response to treatment remain unclear because of small sample sizes and poor generalizability of single-center studies, and disease misclassification in registry-based studies. We therefore aimed to determine the incidence, predictors, and treatment response of recurrent FSGS in a large cohort of kidney transplant recipients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting, participants, &amp; measurements<\/jats:title>\n                    <jats:p>The Post-Transplant Glomerular Disease (TANGO) project is an observational, multicenter, international cohort study that aims to investigate glomerular disease recurrence post-transplantation. Transplant recipients were screened for the diagnosis of idiopathic FSGS between 2005 and 2015 and details were recorded about the transplant, clinical outcomes, treatments, and other risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 11,742 kidney transplant recipients screened for FSGS, 176 had a diagnosis of idiopathic FSGS and were included. FSGS recurred in 57 patients (32%; 95% confidence interval [95% CI], 25% to 39%) and 39% of them lost their graft over a median of 5 (interquartile range, 3.0\u20138.1) years. Multivariable Cox regression revealed a higher risk for recurrence with older age at native kidney disease onset (hazard ratio [HR], 1.37 per decade; 95% CI, 1.09 to 1.56). Other predictors were white race (HR, 2.14; 95% CI, 1.08 to 4.22), body mass index at transplant (HR, 0.89 per kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ; 95% CI, 0.83 to 0.95), and native kidney nephrectomies (HR, 2.76; 95% CI, 1.16 to 6.57). Plasmapheresis and rituximab were the most frequent treatments (81%). Partial or complete remission occurred in 57% of patients and was associated with better graft survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Idiopathic FSGS recurs post-transplant in one third of cases and is associated with a five-fold higher risk of graft loss. Response to treatment is associated with significantly better outcomes but is achieved in only half of the cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.08970719","type":"journal-article","created":{"date-parts":[[2020,1,23]],"date-time":"2020-01-23T16:15:13Z","timestamp":1579796113000},"page":"247-256","source":"Crossref","is-referenced-by-count":195,"title":["Recurrence of FSGS after Kidney Transplantation in Adults"],"prefix":"10.2215","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6108-9828","authenticated-orcid":false,"given":"Audrey","family":"Uffing","sequence":"first","affiliation":[{"name":"Renal Division, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts;"},{"name":"Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jos\u00e9","family":"P\u00e9rez-S\u00e1ez","sequence":"additional","affiliation":[{"name":"Renal Division, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts;"},{"name":"Servicio de Nefrolog\u00eda, Hospital del Mar, Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6297-4909","authenticated-orcid":false,"given":"Marilda","family":"Mazzali","sequence":"additional","affiliation":[{"name":"Division of Nephrology, School of Medical Sciences, University of Campinas (UNICAMP), Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto C.","family":"Manfro","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5041-4792","authenticated-orcid":false,"given":"Andrea Carla","family":"Bauer","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederico","family":"de Sottomaior Drumond","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle M.","family":"O\u2019Shaughnessy","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingxing S.","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuo-Kai","family":"Chin","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlucci G.","family":"Ventura","sequence":"additional","affiliation":[{"name":"Kidney Transplant Service, Hospital das Clinicas\u2013University of Sao Paulo School of Medicine, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4526-4857","authenticated-orcid":false,"given":"Fabiana","family":"Agena","sequence":"additional","affiliation":[{"name":"Kidney Transplant Service, Hospital das Clinicas\u2013University of Sao Paulo School of Medicine, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3310-0484","authenticated-orcid":false,"given":"Elias","family":"David-Neto","sequence":"additional","affiliation":[{"name":"Kidney Transplant Service, Hospital das Clinicas\u2013University of Sao Paulo School of Medicine, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0820-5815","authenticated-orcid":false,"given":"Juliana B.","family":"Mansur","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hospital do Rim, Universidade Federal de Sao Paulo, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1317-4109","authenticated-orcid":false,"given":"Gianna Mastroianni","family":"Kirsztajn","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hospital do Rim, Universidade Federal de Sao Paulo, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helio","family":"Tedesco-Silva","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hospital do Rim, Universidade Federal de Sao Paulo, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto M.V.","family":"Neto","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Hospital do Rim, Universidade Federal de Sao Paulo, Sao Paulo, Brazil;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1729-8152","authenticated-orcid":false,"given":"Carlos","family":"Arias-Cabrales","sequence":"additional","affiliation":[{"name":"Servicio de Nefrolog\u00eda, Hospital del Mar, Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7305-3259","authenticated-orcid":false,"given":"Anna","family":"Buxeda","sequence":"additional","affiliation":[{"name":"Servicio de Nefrolog\u00eda, Hospital del Mar, Barcelona, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Bugnazet","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie Dialyse, Aph\u00e9r\u00e8ses et Transplantation, Grenoble University Hospital, Grenoble, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9016-7506","authenticated-orcid":false,"given":"Thomas","family":"Jouve","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie Dialyse, Aph\u00e9r\u00e8ses et Transplantation, Grenoble University Hospital, Grenoble, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8549-5561","authenticated-orcid":false,"given":"Paolo","family":"Malvezzi","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie Dialyse, Aph\u00e9r\u00e8ses et Transplantation, Grenoble University Hospital, Grenoble, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enver","family":"Akalin","sequence":"additional","affiliation":[{"name":"Montefiore Einstein Center for Transplantation, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Alani","sequence":"additional","affiliation":[{"name":"Montefiore Einstein Center for Transplantation, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaetano","family":"La Manna","sequence":"additional","affiliation":[{"name":"Department of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, St. Orsola Hospital, University of Bologna, Bologna, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgia","family":"Comai","sequence":"additional","affiliation":[{"name":"Department of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, St. Orsola Hospital, University of Bologna, Bologna, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Bini","sequence":"additional","affiliation":[{"name":"Department of Experimental Diagnostic and Specialty Medicine (DIMES), Nephrology, Dialysis and Renal Transplant Unit, St. Orsola Hospital, University of Bologna, Bologna, Italy;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif A.","family":"Muhsin","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel Carlos","family":"Riella","sequence":"additional","affiliation":[{"name":"Pro-Renal Foundation, Curitiba, Paran\u00e1, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia R.","family":"Hokazono","sequence":"additional","affiliation":[{"name":"Pro-Renal Foundation, Curitiba, Paran\u00e1, Brazil; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samira S.","family":"Farouk","sequence":"additional","affiliation":[{"name":"Renal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith","family":"Haverly","sequence":"additional","affiliation":[{"name":"Renal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suraj Sarvode","family":"Mothi","sequence":"additional","affiliation":[{"name":"Renal Division, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2228-4676","authenticated-orcid":false,"given":"Stefan P.","family":"Berger","sequence":"additional","affiliation":[{"name":"Division of Nephrology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7837-0923","authenticated-orcid":false,"given":"Paolo","family":"Cravedi","sequence":"additional","affiliation":[{"name":"Renal Division, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7636-3196","authenticated-orcid":false,"given":"Leonardo V.","family":"Riella","sequence":"additional","affiliation":[{"name":"Renal Division, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,1,23]]},"reference":[{"issue":"Suppl 1","key":"B1-20230813","doi-asserted-by":"crossref","first-page":"A7","DOI":"10.1053\/j.ajkd.2016.12.004","article-title":"US renal data system 2016 annual data report: Epidemiology of kidney disease in the United States.","volume":"69","author":"Saran","year":"2017","journal-title":"Am J Kidney Dis"},{"key":"B2-20230813","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1056\/NEJMra1106556","article-title":"Focal segmental glomerulosclerosis.","volume":"365","author":"D\u2019Agati","year":"2011","journal-title":"N Engl J Med"},{"key":"B4-20230813","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF00858431","article-title":"Recurrence of focal segmental glomerulosclerosis in transplanted kidneys: Analysis of incidence and risk factors in 59 allografts.","volume":"4","author":"Senggutuvan","year":"1990","journal-title":"Pediatr Nephrol"},{"key":"B5-20230813","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1097\/00007890-199010000-00013","article-title":"The recurrence of focal segmental glomerulosclerosis in kidney transplant patients treated with cyclosporine.","volume":"50","author":"Banfi","year":"1990","journal-title":"Transplantation"},{"key":"B6-20230813","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/00007890-199102000-00025","article-title":"Incidence, treatment, and outcome of recurrent focal segmental glomerulosclerosis posttransplantation in 42 allografts in children--a single-center experience.","volume":"51","author":"Ingulli","year":"1991","journal-title":"Transplantation"},{"key":"B7-20230813","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/00007890-199111000-00014","article-title":"Recurrent nephrotic syndrome following renal transplantation in patients with focal glomerulosclerosis. A one-center study of plasma exchange effects.","volume":"52","author":"Dantal","year":"1991","journal-title":"Transplantation"},{"key":"B8-20230813","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S0272-6386(99)70010-7","article-title":"Prediction and treatment of recurrent focal segmental glomerulosclerosis after renal transplantation in children.","volume":"34","author":"Dall\u2019Amico","year":"1999","journal-title":"Am J Kidney Dis"},{"issue":"Suppl","key":"B9-20230813","doi-asserted-by":"crossref","first-page":"S258","DOI":"10.1681\/ASN.V212s258","article-title":"Recurrence of focal segmental glomerulosclerosis posttransplantation: A special report of the North American Pediatric Renal Transplant Cooperative Study.","volume":"2","author":"Tejani","year":"1992","journal-title":"J Am Soc Nephrol"},{"key":"B10-20230813","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1097\/00007890-199601270-00012","article-title":"The influence of native nephrectomy on the incidence of recurrent disease following renal transplantation for primary glomerulonephritis.","volume":"61","author":"Odorico","year":"1996","journal-title":"Transplantation"},{"key":"B11-20230813","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0002-9343(92)90267-F","article-title":"Recurrent focal glomerulosclerosis: Natural history and response to therapy.","volume":"92","author":"Artero","year":"1992","journal-title":"Am J Med"},{"key":"B12-20230813","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3349\/ymj.2001.42.2.209","article-title":"Long-term outcome of kidney transplantation in adult recipients with focal segmental glomerulosclerosis.","volume":"42","author":"Choi","year":"2001","journal-title":"Yonsei Med J"},{"key":"B13-20230813","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1093\/ndt\/gfk005","article-title":"Risk factors and outcome of focal and segmental glomerulosclerosis recurrence in adult renal transplant recipients.","volume":"21","author":"Pardon","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"B14-20230813","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1097\/TP.0b013e31819f12be","article-title":"Kidney transplantation for primary focal segmental glomerulosclerosis: Outcomes and response to therapy for recurrence.","volume":"87","author":"Hickson","year":"2009","journal-title":"Transplantation"},{"key":"B15-20230813","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1111\/j.1432-2277.2009.00977.x","article-title":"Long-term outcome of renal transplantation in adults with focal segmental glomerulosclerosis.","volume":"23","author":"Moroni","year":"2010","journal-title":"Transpl Int"},{"key":"B16-20230813","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1111\/j.1399-3046.2007.00880.x","article-title":"Demographics and response to therapeutic plasma exchange in pediatric renal transplantation for focal glomerulosclerosis: A single center experience.","volume":"12","author":"Mahesh","year":"2008","journal-title":"Pediatr Transplant"},{"key":"B17-20230813","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1111\/j.1399-0012.2008.00908.x","article-title":"Focal segmental glomerular sclerosis in renal transplant recipients: Predicting early disease recurrence may prolong allograft function.","volume":"23","author":"Sener","year":"2009","journal-title":"Clin Transplant"},{"key":"B18-20230813","doi-asserted-by":"crossref","first-page":"173","DOI":"10.5414\/CNP74173","article-title":"Recurrent focal segmental glomerulosclerosis in the renal allograft: Single center experience in the era of modern immunosuppression.","volume":"74","author":"Schachter","year":"2010","journal-title":"Clin Nephrol"},{"key":"B19-20230813","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1093\/ndt\/gfp500","article-title":"Recurrence of nephrotic syndrome after transplantation in a mixed population of children and adults: Course of glomerular lesions and value of the Columbia classification of histological variants of focal and segmental glomerulosclerosis (FSGS).","volume":"25","author":"Canaud","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"B20-20230813","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/1471-2369-14-47","article-title":"A retrospective study of focal segmental glomerulosclerosis: Clinical criteria can identify patients at high risk for recurrent disease after first renal transplantation.","volume":"14","author":"Maas","year":"2013","journal-title":"BMC Nephrol"},{"key":"B21-20230813","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1007\/s00467-018-3994-3","article-title":"Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings.","volume":"33","author":"Pelletier","year":"2018","journal-title":"Pediatr Nephrol"},{"key":"B22-20230813","doi-asserted-by":"crossref","first-page":"506805","DOI":"10.4061\/2011\/506805","article-title":"Recurrent focal segmental glomerulosclerosis in renal allograft recipients: Role of human leukocyte antigen mismatching and other clinical variables.","volume":"2011","author":"Sharief","year":"2011","journal-title":"Int J Nephrol"},{"key":"B23-20230813","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1093\/ndt\/gfr699","article-title":"Outcome of kidney allograft in patients with adulthood-onset focal segmental glomerulosclerosis: Comparison with childhood-onset FSGS.","volume":"27","author":"Hwang","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"B24-20230813","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.kint.2017.03.015","article-title":"Recurrent glomerulonephritis after kidney transplantation: Risk factors and allograft outcomes.","volume":"92","author":"Allen","year":"2017","journal-title":"Kidney Int"},{"key":"B25-20230813","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1186\/s12882-018-1135-7","article-title":"Recurrent glomerulonephritis following renal transplantation and impact on graft survival.","volume":"19","author":"Jiang","year":"2018","journal-title":"BMC Nephrol"},{"key":"B26-20230813","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.2215\/CJN.03060316","article-title":"Long-Term outcome of kidney transplantation in recipients with focal segmental glomerulosclerosis.","volume":"11","author":"Francis","year":"2016","journal-title":"Clin J Am Soc Nephrol"},{"key":"B27-20230813","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1097\/TP.0b013e31829c2431","article-title":"Focal segmental glomerulosclerosis in children: Multivariate analysis indicates that donor type does not alter recurrence risk.","volume":"96","author":"Nehus","year":"2013","journal-title":"Transplantation"},{"key":"B28-20230813","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.2215\/CJN.03550410","article-title":"Discrepancy between Medical Evidence Form 2728 and renal biopsy for glomerular diseases.","volume":"5","author":"Layton","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"B29-20230813","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/cts.12178","article-title":"Big data and large sample size: A cautionary note on the potential for bias.","volume":"7","author":"Kaplan","year":"2014","journal-title":"Clin Transl Sci"},{"key":"B30-20230813","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1186\/s12882-018-1025-z","article-title":"A large, international study on post-transplant glomerular diseases: The TANGO project.","volume":"19","author":"Uffing","year":"2018","journal-title":"BMC Nephrol"},{"key":"B31-20230813","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/petr.12766","article-title":"Role of race in kidney transplant outcomes in children with focal segmental glomerulosclerosis.","volume":"20","author":"Guan","year":"2016","journal-title":"Pediatr Transplant"},{"key":"B32-20230813","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nrn3475","article-title":"Power failure: Why small sample size undermines the reliability of neuroscience.","volume":"14","author":"Button","year":"2013","journal-title":"Nat Rev Neurosci"},{"key":"B33-20230813","doi-asserted-by":"crossref","first-page":"R2","DOI":"10.1186\/cc11919","article-title":"Small studies may overestimate the effect sizes in critical care meta-analyses: A meta-epidemiological study.","volume":"17","author":"Zhang","year":"2013","journal-title":"Crit Care"},{"key":"B34-20230813","doi-asserted-by":"crossref","first-page":"982","DOI":"10.7326\/0003-4819-135-11-200112040-00010","article-title":"Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses.","volume":"135","author":"Kjaergard","year":"2001","journal-title":"Ann Intern Med"},{"key":"B35-20230813","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.kint.2018.07.024","article-title":"Identification of genetic causes for sporadic steroid-resistant nephrotic syndrome in adults.","volume":"94","author":"Gribouval","year":"2018","journal-title":"Kidney Int"},{"key":"B36-20230813","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1046\/j.1523-1755.1999.00727.x","article-title":"Spectrum of disease in familial focal and segmental glomerulosclerosis.","volume":"56","author":"Conlon","year":"1999","journal-title":"Kidney Int"},{"key":"B37-20230813","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/ki.2008.650","article-title":"Clinical and epidemiological assessment of steroid-resistant nephrotic syndrome associated with the NPHS2 R229Q variant.","volume":"75","author":"Machuca","year":"2009","journal-title":"Kidney Int"},{"key":"B38-20230813","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1053\/ajkd.2001.21311","article-title":"Graft loss due to recurrent focal segmental glomerulosclerosis in renal transplant recipients in the United States.","volume":"37","author":"Abbott","year":"2001","journal-title":"Am J Kidney Dis"},{"key":"B39-20230813","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1681\/ASN.2011040388","article-title":"APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy.","volume":"22","author":"Kopp","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"B40-20230813","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1681\/ASN.2010010029","article-title":"Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation.","volume":"22","author":"Jungraithmayr","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"B41-20230813","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1007\/s00467-006-0361-6","article-title":"Recurrence of nephrotic syndrome\/focal segmental glomerulosclerosis following renal transplantation in children.","volume":"22","author":"Fine","year":"2007","journal-title":"Pediatr Nephrol"},{"key":"B42-20230813","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/ndt\/gfu035","article-title":"Focal segmental glomerulosclerosis: Towards a better understanding for the practicing nephrologist.","volume":"30","author":"Sethi","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"B43-20230813","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3109\/01913123.2011.584657","article-title":"Clinicopathological characteristics of obesity-associated focal segmental glomerulosclerosis.","volume":"35","author":"Darouich","year":"2011","journal-title":"Ultrastruct Pathol"},{"key":"B44-20230813","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/j.1600-6143.2009.02580.x","article-title":"Intensive and prolonged treatment of focal and segmental glomerulosclerosis recurrence in adult kidney transplant recipients: A pilot study.","volume":"9","author":"Canaud","year":"2009","journal-title":"Am J Transplant"},{"key":"B45-20230813","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/TP.0000000000001160","article-title":"Rituximab for recurrence of primary focal segmental glomerulosclerosis after kidney transplantation: Clinical outcomes.","volume":"101","author":"Garrouste","year":"2017","journal-title":"Transplantation"},{"key":"B46-20230813","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1097\/TP.0000000000002008","article-title":"Rituximab and therapeutic plasma exchange in recurrent focal segmental glomerulosclerosis postkidney transplantation.","volume":"102","author":"Alasfar","year":"2018","journal-title":"Transplantation"},{"key":"B47-20230813","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/ajt.12045","article-title":"Recent progress in the pathophysiology and treatment of FSGS recurrence.","volume":"13","author":"Cravedi","year":"2013","journal-title":"Am J Transplant"},{"key":"B49-20230813","doi-asserted-by":"crossref","first-page":"481","DOI":"10.2215\/CJN.04800908","article-title":"Calcineurin inhibitor nephrotoxicity.","volume":"4","author":"Naesens","year":"2009","journal-title":"Clin J Am Soc Nephrol"}],"container-title":["Clinical Journal of the American Society of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.2215\/CJN.08970719","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T13:42:16Z","timestamp":1786369336000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.2215\/CJN.08970719"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,23]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.2215\/cjn.08970719","relation":{},"ISSN":["1555-9041","1555-905X"],"issn-type":[{"value":"1555-9041","type":"print"},{"value":"1555-905X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,23]]}}}