{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:46:38Z","timestamp":1786373198194,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>A recent meta-analysis found that about 30% of women with a previous preeclamptic pregnancy had persistent microalbuminuria at follow-up. The analysis was, however, based on small studies, and more data are needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting, participants, &amp; measurements<\/jats:title>\n                    <jats:p>Using data from the Medical Birth Registry in Norway, this study identified women with or without preeclampsia in their first pregnancy 9\u201311 years previously (1998\u20132000). Women with diabetes, rheumatic disease, essential hypertension, or renal disease before first pregnancy and\/or preeclampsia in later pregnancies were excluded. Eighty-nine women with and 69 women without preeclampsia participated in the study. Urinary albumin-to-creatinine ratio (ACR) was measured in three morning urine samples. Estimated GFR (eGFR) was calculated using the CKD-Epidemiology Collaboration formula.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Median urinary ACR in follow-up urine samples was 0.53 mg\/mmol for women with and 0.50 mg\/mmol for women without preeclampsia (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.54). Only one woman (1%) with previous preeclampsia had urinary ACR &gt;2.5 mg\/mmol in two of three urine samples. Preeclampsia was not associated with urinary ACR above the 75th percentile. Women with preeclampsia did not have significantly higher eGFR than women without preeclampsia (107.9 versus 104.9 ml\/min per 1.73 m\n                      <jats:sup>2<\/jats:sup>\n                      ;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.12), but preterm preeclampsia was significantly associated with eGFR above the 75th percentile (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.03).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this population-based study of otherwise healthy women, preeclampsia 10 years earlier was not associated with increased risk of persisting microalbuminuria. Estimated GFR was not significantly different between women with and those without preeclampsia, but preterm preeclampsia was associated with high normal eGFR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2215\/cjn.10641012","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T20:15:46Z","timestamp":1369944946000},"page":"1126-1134","source":"Crossref","is-referenced-by-count":45,"title":["Preeclampsia and Prevalence of Microalbuminuria 10 Years Later"],"prefix":"10.2215","volume":"8","author":[{"given":"Miriam Kristine","family":"Sandvik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein","family":"Hallan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Einar","family":"Svarstad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rn Egil","family":"Vikse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20230811","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1056\/NEJMoa0706790","article-title":"Preeclampsia and the risk of end-stage renal disease.","volume":"359","author":"Vikse","year":"2008","journal-title":"N Engl J Med"},{"key":"R2-11-20230811","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1053\/j.ajkd.2009.12.036","article-title":"Kidney disease after preeclampsia: a systematic review and meta-analysis.","volume":"55","author":"McDonald","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"R3-11-20230811","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/bmj.39335.385301.BE","article-title":"Pre-eclampsia and risk of cardiovascular disease and cancer in later life: Systematic review and meta-analysis.","volume":"335","author":"Bellamy","year":"2007","journal-title":"BMJ"},{"key":"R4-11-20230811","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1136\/bmj.323.7323.1213","article-title":"Long term mortality of mothers and fathers after pre-eclampsia: Population based cohort study.","volume":"323","author":"Irgens","year":"2001","journal-title":"BMJ"},{"key":"R5-11-20230811","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ahj.2008.06.042","article-title":"Cardiovascular sequelae of preeclampsia\/eclampsia: A systematic review and meta-analyses.","volume":"156","author":"McDonald","year":"2008","journal-title":"Am Heart J"},{"key":"R6-11-20230811","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/ndt\/14.5.1129","article-title":"Microalbuminuria after pregnancy complicated by pre-eclampsia.","volume":"14","author":"Bar","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"R7-11-20230811","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1111\/j.1471-0528.1995.tb10874.x","article-title":"Blood pressure and renal function seven years after pregnancy complicated by hypertension.","volume":"102","author":"Nisell","year":"1995","journal-title":"Br J Obstet Gynaecol"},{"key":"R8-11-20230811","doi-asserted-by":"crossref","first-page":"3289","DOI":"10.1093\/ndt\/gfq169","article-title":"Previous preeclampsia and risk for progression of biopsy-verified kidney disease to end-stage renal disease.","volume":"25","author":"Vikse","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"R9-11-20230811","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1034\/j.1600-0412.2000.079006435.x","article-title":"The Medical Birth Registry of Norway. 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