{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:35:18Z","timestamp":1790717718614,"version":"4.1.0"},"reference-count":97,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["CJASN"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Cancer is an important outcome after kidney transplantation because it is the second leading cause of death in most Western countries. The excess risk of cancer after transplantation is approximately two to three times higher than the age- and sex-matched general population, driven largely by viral- and immune-related cancers. Once cancer develops, outcomes are generally poor, particularly for those with melanoma, renal cell carcinoma, and post-transplant lymphoproliferative disease. More importantly, effective screening and treatment strategies are limited in this high-risk population. In this review, we begin with a patient\u2019s journey that maps the experience of living with a kidney transplant and understand the patient\u2019s knowledge, education, and experience of cancer in the context of transplantation. The epidemiology and burden of cancer in recipients of kidney transplants, along with the up-to-date screening and treatment strategies, are discussed. We also focus on the current understanding of optimal care for recipients of kidney transplants who are living with cancer from the patients\u2019 perspectives.<\/jats:p>","DOI":"10.2215\/cjn.14570920","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T15:20:19Z","timestamp":1617031219000},"page":"434-443","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":113,"title":["De Novo Malignancies after Kidney Transplantation"],"prefix":"10.2215","volume":"17","author":[{"given":"David","family":"Al-Adra","sequence":"first","affiliation":[{"name":"Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talal","family":"Al-Qaoud","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9240-1308","authenticated-orcid":false,"given":"Kevin","family":"Fowler","sequence":"additional","affiliation":[{"name":"The Voice of the Patient, Inc., Columbia, Missouri"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germaine","family":"Wong","sequence":"additional","affiliation":[{"name":"Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia"},{"name":"Centre for Kidney Research, Kids Research Institute, The Children\u2019s Hospital at Westmead, Westmead, New South Wales, Australia"},{"name":"Centre for Transplant and Renal Research, Westmead Hospital, Westmead, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3]]},"reference":[{"key":"B1-20241015","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/ki.1996.307","article-title":"A study of the quality of life and cost-utility of renal transplantation","volume":"50","author":"Laupacis","year":"1996","journal-title":"Kidney Int"},{"key":"B2-20241015","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1056\/NEJM199912023412303","article-title":"Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant","volume":"341","author":"Wolfe","year":"1999","journal-title":"N Engl J Med"},{"key":"B3-20241015","doi-asserted-by":"crossref","first-page":"e29591","DOI":"10.1371\/journal.pone.0029591","article-title":"Comparative survival and economic benefits of deceased donor kidney transplantation and dialysis in people with 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