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Yasminelle is unlike other low-dose ethinyl estradiol combined oral contraceptives, since drospirenone produces antiandrogenic and antimineralocorticoid effects that offer various benefits including a reduced potential for estrogen-induced water retention. Pharmacological and pharmacokinetic data have been derived from clinical experience with ethinyl estradiol 30 \u03bcg and drospirenone 3 mg (Yasmin\u00ae). Clinical studies with Yasminelle have shown a high degree of contraceptive efficacy, similar to that of combined oral contraceptives that contain a low dose of ethinyl estradiol combined with other progestins. These studies have also demonstrated that Yasminelle produces excellent cycle control and has a good tolerability profile, similar to that of other low-dose ethinyl estradiol combined oral contraceptives. <\/jats:p>","DOI":"10.2217\/17455057.2.4.551","type":"journal-article","created":{"date-parts":[[2006,6,28]],"date-time":"2006-06-28T15:02:29Z","timestamp":1151506949000},"page":"551-559","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Yasminelle\u00ae: A New Low-Dose Combined Oral Contraceptive Containing Drospirenone"],"prefix":"10.1177","volume":"2","author":[{"given":"Martin","family":"Sillem","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynaecology, DRK Krankenhaus, Marktstr. 104, D-56564 Neuwied, Germany, Tel.: +49 2631 98 1601; Fax: +49 2631 98 1690;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2006,7,1]]},"reference":[{"key":"bibr1-17455057.2.4.551","first-page":"779","volume-title":"Contraceptive Technology","author":"Trussell J","year":"1998","edition":"17"},{"key":"bibr2-17455057.2.4.551","unstructured":"Shvarts S, Besinque K, Atkinson R, Gill M: New advances in contraception. 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