{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:50:56Z","timestamp":1762505456721,"version":"3.38.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T00:00:00Z","timestamp":1220227200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:p> A pregnancy of unknown location (PUL) is a descriptive term used to classify a woman when she has a positive pregnancy test but no intra- or extra-uterine pregnancy is visualized on transvaginal sonography. Expectant management has been shown to be safe for the majority of women with a PUL. Serum progesterone and human chorionic gonadotrophin levels as well as mathematical models play a role in predicting the final outcomes of PULs, which include intrauterine pregnancy, failing PUL and ectopic pregnancy. Other possible predictors of outcome have been studied, but currently no factor has been identified that combines accuracy with reproducibility and simplicity. This article discusses the various aspects of the management of women with PULs. Future work should be aimed at prospectively testing current models in order to predict the outcome of a PUL and minimizing follow-up. <\/jats:p>","DOI":"10.2217\/17455057.4.5.491","type":"journal-article","created":{"date-parts":[[2009,1,7]],"date-time":"2009-01-07T13:01:35Z","timestamp":1231333295000},"page":"491-499","source":"Crossref","is-referenced-by-count":9,"title":["Predicting Outcomes in Pregnancies of Unknown Location"],"prefix":"10.1177","volume":"4","author":[{"given":"Emma","family":"Kirk","sequence":"first","affiliation":[{"name":"Early Pregnancy & Gynaecology Ultrasound Unit, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK, Tel.: + 44 79 7421 4125; Fax: +44 20 8725 0094;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Bourne","sequence":"additional","affiliation":[{"name":"Early Pregnancy & Gynaecology Ultrasound Unit, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK, Tel.: + 44 79 7421 4125; Fax: +44 20 8725 0094;"},{"name":"Department of Obstetrics & Gynaecology, University Hospital Gasthuisberg, KU Leuven, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,9,1]]},"reference":[{"key":"bibr1-17455057.4.5.491","first-page":"158","volume":"108","author":"Banerjee S","year":"2001","journal-title":"BJOG"},{"key":"bibr2-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2004.04.004"},{"key":"bibr3-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem283"},{"key":"bibr4-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a136123"},{"key":"bibr5-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.1999.14040231.x"},{"key":"bibr6-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1988.tb12804.x"},{"key":"bibr7-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem073"},{"key":"bibr8-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2838"},{"volume-title":"The management of early pregnancy loss","year":"2006","author":"Royal College of Obstetricians and Gynaecologists (RCOG)","key":"bibr9-17455057.4.5.491"},{"key":"bibr10-17455057.4.5.491","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/13.11.3220"},{"key":"bibr11-17455057.4.5.491","first-page":"357","volume":"66","author":"Romero R","year":"1985","journal-title":"Obstet. 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