{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:47:24Z","timestamp":1761155244477,"version":"3.38.0"},"reference-count":45,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Womens Health (Lond Engl)"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p> The reduced capacity of older skin to synthesize vitamin D<jats:sub>3<\/jats:sub> under the influence of ultraviolet light makes older persons at risk of vitamin D deficiency. The risk could even be increased in institutionalized persons owing to their lower sunshine exposure. It has been reported that an inadequate vitamin D level is associated with secondary hyperparathyroidism, increased bone turnover, and bone loss, which increase fracture risk. The objective of this study was to assess the prevalence of inadequate serum vitamin D levels in institutionalized, postmenopausal, osteoporotic women. Assessment of 25-hydroxyvitamin D [25(OH)D] was performed in 445 institutionalized, osteoporotic women from nine countries (Australia, Belgium, France, Germany, Hungary, Italy, Poland, Spain and UK). For each institutionalized woman, three age-matched, noninstitutionalized, osteoporotic controls were also included. Four cutoffs of 25(OH)D inadequacy were fixed: less than 80, less than 75, less than 50 and less than 30 nmol\/l. Mean age was 79.7 years (standard deviation [SD] = 5.8) for the institutionalized women and 79.5 years (SD = 5.5) for the noninstitutionalized women (p = 0.45). Significantly fewer institutionalized women received vitamin D supplements (13.2 vs 24.0%; p &lt; 0.0001). In women without vitamin D supplements, the level of 25(OH)D was significantly lower in institutionalized women (56.9 [SD = 23.9] nmol\/l) compared with noninstitutionalized women (63.2 [SD = 22.0] nmol\/l; p &lt; 0.0001). In institutionalized women (without vitamin D supplements), the prevalence of 25(OH)D inadequacy was 10.4, 41.2, 80.3 and 84.2% when considering cutoffs of 80, 75, 50 and 30 nmol\/l, respectively. In the control group, the prevalence was 2.7, 22.9, 74.4 and 81.7%, respectively. The prevalence of vitamin D inadequacy was significantly higher in institutionalized women when considering the 75, 50 and 30 nmol\/l cutoffs but not when considering the 80 nmol\/l cutoff. This study highlights a high prevalence of vitamin D inadequacy in institutionalized, osteoporotic women. Compared with age-matched osteoporotic controls, the prevalence of severe vitamin D inadequacy was substantially more important in institutionalized women. We believe that a greater awareness of the importance of vitamin D inadequacy is needed in order to address this public health problem. <\/jats:p>","DOI":"10.2217\/17455057.5.1.49","type":"journal-article","created":{"date-parts":[[2009,1,16]],"date-time":"2009-01-16T16:54:25Z","timestamp":1232124865000},"page":"49-54","source":"Crossref","is-referenced-by-count":25,"title":["Highest Prevalence of Vitamin D Inadequacy in Institutionalized Women Compared with Noninstitutionalized Women: A Case\u2013Control Study"],"prefix":"10.1177","volume":"5","author":[{"given":"Olivier","family":"Bruyere","sequence":"first","affiliation":[{"name":"Olivier Bruyere, University of Li\u00e8ge, Department of Public Health, Epidemiology & Health Economics, CHU Sart-Tilman, B\u00e2t B23, 4000 Li\u00e8ge, Belgium, Tel.: +32 436 625 81, Fax: +32 436 628 12,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Decock","sequence":"additional","affiliation":[{"name":"Caroline Decock, WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders & Department of Public Health, Epidemiology & Health Economics, University of Liege, Liege, Belgium, Tel.: +32 436 625 81, Fax: +32 436 628 12,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Delhez","sequence":"additional","affiliation":[{"name":"Melanie Delhez, WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders & Department of Public Health, Epidemiology & Health Economics, University of Liege, Liege, Belgium, Tel.: +32 436 625 81, Fax: +32 436 628 12"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Collette","sequence":"additional","affiliation":[{"name":"Julien Collette, WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders & Department of Public Health, Epidemiology & Health Economics, University of Liege, Liege, Belgium, Tel.: +32 436 676 87, Fax: +32 436 628 12,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Yves","family":"Reginster","sequence":"additional","affiliation":[{"name":"Jean-Yves Reginster, WHO Collaborating Center for Public Health Aspect of Osteoarticular Disorders & Department of Public Health, Epidemiology & Health Economics, University of Liege, Liege, Belgium, Tel.: +32 426 625 01, Fax: +32 436 628 12,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,1,1]]},"reference":[{"key":"bibr00101-17455057.5.1.49","unstructured":"Papers of special note have been highlighted as:"},{"key":"bibr00102-17455057.5.1.49","unstructured":"of interest"},{"key":"bibr00103-17455057.5.1.49","unstructured":"of considerable interest"},{"key":"bibr1-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.3.752"},{"key":"bibr2-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2003.18.2.343"},{"key":"bibr3-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51510.x"},{"key":"bibr4-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-004-1812-1"},{"key":"bibr5-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-005-1894-4"},{"key":"bibr6-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-008-0560-z"},{"key":"bibr40-17455057.5.1.49","unstructured":"Constitutes a roadmap to practically implement assessment of osteoporosis at the primary healthcare level."},{"key":"bibr7-17455057.5.1.49","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2007.10.005"},{"issue":"2","key":"bibr8-17455057.5.1.49","first-page":"213","volume":"55","author":"Barragry JM","year":"1978","journal-title":"Clin. 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