{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T02:31:04Z","timestamp":1780453864126,"version":"3.54.1"},"reference-count":200,"publisher":"Informa UK Limited","issue":"6","funder":[{"name":"B Braun\/Aesculap"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomarkers Med."],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.2217\/bmm.09.37","type":"journal-article","created":{"date-parts":[[2009,12,15]],"date-time":"2009-12-15T15:32:07Z","timestamp":1260891127000},"page":"787-805","source":"Crossref","is-referenced-by-count":28,"title":["Ongoing Search for Diagnostic Biomarkers in Idiopathic Normal Pressure Hydrocephalus"],"prefix":"10.1080","volume":"3","author":[{"given":"Andrew","family":"Tarnaris","sequence":"first","affiliation":[{"name":"Department of Neurosurgery,National Hospital for Neurology & Neurosurgery,\rBox 32, Queen Square,\rLondon,\rWC1N 3BG,\rUK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed K","family":"Toma","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,National Hospital for Neurology & Neurosurgery,\rBox 32, Queen Square,\rLondon,\rWC1N 3BG,\rUK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil D","family":"Kitchen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,National Hospital for Neurology & Neurosurgery,\rBox 32, Queen Square,\rLondon,\rWC1N 3BG,\rUK."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence D","family":"Watkins","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery,National Hospital for Neurology & Neurosurgery,\rBox 32, Queen Square,\rLondon,\rWC1N 3BG,\rUK."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2009,12,15]]},"reference":[{"key":"e_1_3_3_3_1_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.48.S1"},{"key":"e_1_3_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0785"},{"key":"e_1_3_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-9877(03)00330-X"},{"key":"e_1_3_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2004.03.029"},{"key":"e_1_3_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000168184.01002.60"},{"key":"e_1_3_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(03)00487-3"},{"issue":"1","key":"e_1_3_3_3_7_1","first-page":"19","article-title":"The differential diagnosis of Alzheimer's disease. Cerebral atrophy versus normal pressure hydrocephalus","volume":"5","author":"George AE","year":"1995","unstructured":"George AE , HolodnyA, GolombJ, de LeonMJ: The differential diagnosis of Alzheimer's disease. Cerebral atrophy versus normal pressure hydrocephalus. Neuroimaging Clin. N. Am.5(1) , 19 (1995).","journal-title":"Neuroimaging Clin. N. Am."},{"key":"e_1_3_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneuro1004"},{"key":"e_1_3_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000168185.29659.C5"},{"key":"e_1_3_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003290050082"},{"key":"e_1_3_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2176"},{"key":"e_1_3_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(98)00022-0"},{"key":"e_1_3_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.3171\/2007.9.17572"},{"key":"e_1_3_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8454-3-11"},{"key":"e_1_3_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.1000211"},{"key":"e_1_3_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(94)90064-7"},{"key":"e_1_3_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.6.778"},{"key":"e_1_3_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01593.x"},{"key":"e_1_3_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00890.x"},{"key":"e_1_3_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00313729"},{"issue":"9","key":"e_1_3_3_3_21_1","first-page":"1021","article-title":"Three decades of normal pressure hydrocephalus: are we wiser now?","volume":"57","author":"Vanneste JA","year":"1994","unstructured":"Vanneste JA : Three decades of normal pressure hydrocephalus: are we wiser now?BMJ57(9) , 1021\u20131025 (1994).","journal-title":"BMJ"},{"key":"e_1_3_3_3_22_1","first-page":"632","article-title":"CSF shunts for dementia, incontinence, and gait disturbance.","volume":"32","author":"Black PM","year":"1985","unstructured":"Black PM , OjemannRG, TzourasA: CSF shunts for dementia, incontinence, and gait disturbance.Clin. Neurosurg.32, 632 (1985).","journal-title":"Clin. Neurosurg."},{"key":"e_1_3_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.13.4913"},{"key":"e_1_3_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308809"},{"key":"e_1_3_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1819.2000.00658.x"},{"key":"e_1_3_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1999.0720741.x"},{"key":"e_1_3_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-003-0075-x"},{"key":"e_1_3_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2008-14102"},{"key":"e_1_3_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02815140"},{"key":"e_1_3_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007020170091"},{"key":"e_1_3_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.8.1133"},{"issue":"10","key":"e_1_3_3_3_32_1","first-page":"911","article-title":"CSF and plasma vasopressin concentrations in dementia.","volume":"46","author":"S\u2298rensen PS","year":"1983","unstructured":"S\u2298rensen PS , HammerM, VorstrupS, GjerrisF: CSF and plasma vasopressin concentrations in dementia.BMJ46(10) , 911\u2013916 (1983).","journal-title":"BMJ"},{"key":"e_1_3_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(83)90189-2"},{"key":"e_1_3_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00313833"},{"key":"e_1_3_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00319684"},{"key":"e_1_3_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1985.tb00912.x"},{"key":"e_1_3_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(85)90168-6"},{"key":"e_1_3_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.4.592"},{"key":"e_1_3_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2003.026013"},{"key":"e_1_3_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2006.01.014"},{"issue":"7","key":"e_1_3_3_3_41_1","first-page":"455","article-title":"Cerebrospinal fluid interleukin-1\u03b2 (IL-1\u03b2) in Alzheimer's disease and neurological disorders","volume":"13","author":"Cacabelos R","year":"1991","unstructured":"Cacabelos R , BarqueroM, GarciaP, AlvarezXA, Varela de SeijasE: Cerebrospinal fluid interleukin-1\u03b2 (IL-1\u03b2) in Alzheimer's disease and neurological disorders. Methods Find. Exp. Clin. Pharmacol.13(7) , 455 (1991).","journal-title":"Methods Find. Exp. Clin. Pharmacol."},{"key":"e_1_3_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1159\/000106627"},{"key":"e_1_3_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.3.252"},{"key":"e_1_3_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.69.1.74"},{"key":"e_1_3_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.01189.x"},{"key":"e_1_3_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1159\/000101843"},{"key":"e_1_3_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1996.67052013.x"},{"key":"e_1_3_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1159\/000116653"},{"key":"e_1_3_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20681"},{"key":"e_1_3_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2003.08.009"},{"key":"e_1_3_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20266"},{"key":"e_1_3_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncpneuro0688"},{"key":"e_1_3_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8454-4-7"},{"key":"e_1_3_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870120110"},{"key":"e_1_3_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.70.3.289"},{"key":"e_1_3_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.2.294"},{"key":"e_1_3_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(88)90257-2"},{"key":"e_1_3_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380414"},{"key":"e_1_3_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1087753"},{"key":"e_1_3_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-006-0562-6"},{"key":"e_1_3_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199004000-00015"},{"key":"e_1_3_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/105.1.65"},{"key":"e_1_3_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.5.0855"},{"issue":"7","key":"e_1_3_3_3_64_1","first-page":"1277","article-title":"CSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry.","volume":"19","author":"Kitagaki H","year":"1998","unstructured":"Kitagaki H : CSF spaces in idiopathic normal pressure hydrocephalus: morphology and volumetry.AJNR Am. J. Neuroradiol.19(7) , 1277\u20131284 (1998).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-007-0318-x"},{"key":"e_1_3_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1159\/000119521"},{"issue":"7","key":"e_1_3_3_3_67_1","first-page":"1285","article-title":"MR prediction of shunt response in NPH: CSF morphology versus physiology","volume":"19","author":"Bradley W","year":"1998","unstructured":"Bradley W Jr : MR prediction of shunt response in NPH: CSF morphology versus physiology. AJNR Am. J. Neuroradiol.19(7) , 1285\u20131286 (1998).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.7887\/jcns.15.619"},{"key":"e_1_3_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-007-1142-0"},{"key":"e_1_3_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1044-4"},{"issue":"5","key":"e_1_3_3_3_71_1","first-page":"813","article-title":"MR differential diagnosis of normal-pressure hydrocephalus and Alzheimer disease: significance of perihippocampal fissures.","volume":"19","author":"Holodny A","year":"1998","unstructured":"Holodny A : MR differential diagnosis of normal-pressure hydrocephalus and Alzheimer disease: significance of perihippocampal fissures.AJNR Am. J. Neuroradiol.19(5) , 813\u2013819 (1998).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-006-0074-6"},{"key":"e_1_3_3_3_73_1","first-page":"354","article-title":"Magnetic resonance imaging, unstable intracranial pressure and clinical outcome in patients with normal pressure hydrocephalus.","volume":"71","author":"Qureshi AI","year":"1998","unstructured":"Qureshi AI , WilliamsMA, RazumovskyAY, HanleyDF: Magnetic resonance imaging, unstable intracranial pressure and clinical outcome in patients with normal pressure hydrocephalus.Acta Neurochir. Suppl.71, 354\u2013356 (1998).","journal-title":"Acta Neurochir. Suppl."},{"issue":"4","key":"e_1_3_3_3_74_1","first-page":"395","article-title":"Functional and magnetic resonance imaging correlates of corpus callosum in normal pressure hydrocephalus before and after shunting.","volume":"78","author":"Mataro M","year":"2007","unstructured":"Mataro M , MatarinM, PocaMet al.: Functional and magnetic resonance imaging correlates of corpus callosum in normal pressure hydrocephalus before and after shunting.BMJ78(4) , 395\u2013398 (2007).","journal-title":"BMJ"},{"key":"e_1_3_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-198711000-00001"},{"key":"e_1_3_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-005-0791-2"},{"key":"e_1_3_3_3_77_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000232655.78335.D5"},{"key":"e_1_3_3_3_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00395252"},{"key":"e_1_3_3_3_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-211-30714-1_72"},{"key":"e_1_3_3_3_80_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.5.0855"},{"key":"e_1_3_3_3_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410200306"},{"key":"e_1_3_3_3_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0928-1"},{"issue":"1","key":"e_1_3_3_3_83_1","first-page":"31","article-title":"Association of deep white matter infarction with chronic communicating hydrocephalus: implications regarding the possible origin of normal-pressure hydrocephalus","volume":"12","author":"Bradley W","year":"1991","unstructured":"Bradley W Jr : Association of deep white matter infarction with chronic communicating hydrocephalus: implications regarding the possible origin of normal-pressure hydrocephalus. AJNR Am. J. Neuroradiol.12(1) , 31\u201339 (1991).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_84_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199703000-00011"},{"key":"e_1_3_3_3_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050040"},{"key":"e_1_3_3_3_86_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.01189.x"},{"key":"e_1_3_3_3_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2007.07.012"},{"key":"e_1_3_3_3_88_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199608000-00011"},{"issue":"9","key":"e_1_3_3_3_89_1","first-page":"1665","article-title":"Normal pressure hydrocephalus: vascular white matter changes on MR images must not exclude patients from shunt surgery.","volume":"22","author":"Tullberg M","year":"2001","unstructured":"Tullberg M , JensenC, EkholmS, WikkelsoC: Normal pressure hydrocephalus: vascular white matter changes on MR images must not exclude patients from shunt surgery.AJNR Am. J. Neuroradiol.22(9) , 1665\u20131673 (2001).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_90_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000168185.29659.C5"},{"key":"e_1_3_3_3_91_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1996.84.6.0972"},{"issue":"9","key":"e_1_3_3_3_92_1","first-page":"1479","article-title":"Increased intracranial volume: a clue to the etiology of idiopathic normal-pressure hydrocephalus?","volume":"25","author":"Bradley W","year":"2004","unstructured":"Bradley W , SafarF, HurtadoC, OrdJ, AlksneJ: Increased intracranial volume: a clue to the etiology of idiopathic normal-pressure hydrocephalus?AJNR Am. J. Neuroradiol.25(9) , 1479\u20131484 (2004).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007010170079"},{"key":"e_1_3_3_3_94_1","first-page":"371","article-title":"Differential diagnosis of NPH and brain atrophy assessed by measurement of intracranial and ventricular CSF volume with 3D FASE MRI.","volume":"71","author":"Yoshihara M","year":"1998","unstructured":"Yoshihara M , TsunodaA, SatoK, KanayamaS, CalderonA: Differential diagnosis of NPH and brain atrophy assessed by measurement of intracranial and ventricular CSF volume with 3D FASE MRI.Acta Neurochir. Suppl.71, 371\u2013374 (1998).","journal-title":"Acta Neurochir. Suppl."},{"key":"e_1_3_3_3_95_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002349900241"},{"key":"e_1_3_3_3_96_1","first-page":"76","article-title":"Intracranial compartment volumes in normal pressure hydrocephalus: volumetric assessment versus outcome.","volume":"27","author":"Palm WM","year":"2006","unstructured":"Palm WM , WalchenbachR, BruinsmaBet al.: Intracranial compartment volumes in normal pressure hydrocephalus: volumetric assessment versus outcome.Am. Soc. Neuroradiol.27, 76\u201379 (2006)","journal-title":"Am. Soc. Neuroradiol."},{"key":"e_1_3_3_3_97_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2002.97.1.0073"},{"key":"e_1_3_3_3_98_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2004.100.6.1036"},{"key":"e_1_3_3_3_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-003-0989-x"},{"key":"e_1_3_3_3_100_1","first-page":"533","article-title":"Is decreased ventricular volume a correlate of positive clinical outcome following shunt placement in cases of normal pressure hydrocephalus?","volume":"86","author":"Meier U","year":"2003","unstructured":"Meier U , ParisS, GraweA, StockheimD, HajdukovaA, MutzeS: Is decreased ventricular volume a correlate of positive clinical outcome following shunt placement in cases of normal pressure hydrocephalus?Acta Neurochir. Suppl.86, 533\u2013537 (2003).","journal-title":"Acta Neurochir. Suppl."},{"issue":"5","key":"e_1_3_3_3_101_1","first-page":"353","article-title":"Brain CT scan indexes in the normal pressure hydrocephalus: predictive value in the outcome of patients and correlation to the clinical symptoms.","volume":"79","author":"Chatzidakis E","year":"2008","unstructured":"Chatzidakis E , BarlasG, CondilisNet al.: Brain CT scan indexes in the normal pressure hydrocephalus: predictive value in the outcome of patients and correlation to the clinical symptoms.Ann. Ital. Chir.79(5) , 353\u2013362 (2008).","journal-title":"Ann. Ital. Chir."},{"key":"e_1_3_3_3_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00698846"},{"key":"e_1_3_3_3_103_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.89.5.0742"},{"key":"e_1_3_3_3_104_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-1044-4"},{"issue":"5","key":"e_1_3_3_3_105_1","first-page":"590","article-title":"Hippocampal atrophy correlates with severe cognitive impairment in elderly patients with suspected normal pressure hydrocephalus","volume":"57","author":"Golomb J","year":"1994","unstructured":"Golomb J , De LeonM, GeorgeAet al.: Hippocampal atrophy correlates with severe cognitive impairment in elderly patients with suspected normal pressure hydrocephalus. BMJ57(5) , 590\u2013593 (1994).","journal-title":"BMJ"},{"issue":"2","key":"e_1_3_3_3_106_1","first-page":"409","article-title":"MR imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical Alzheimer's disease confirmed by pathologic analysis.","volume":"21","author":"Savolainen S","year":"2000","unstructured":"Savolainen S , LaaksoM, PaljarviLet al.: MR imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical Alzheimer's disease confirmed by pathologic analysis.AJNR Am. J. Neuroradiol.21(2) , 409\u2013414 (2000).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_107_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2007.00906.x"},{"key":"e_1_3_3_3_108_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2002.01329.x"},{"key":"e_1_3_3_3_109_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198911000-00013"},{"key":"e_1_3_3_3_110_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1994.11740261"},{"key":"e_1_3_3_3_111_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2001.00092.x"},{"issue":"3","key":"e_1_3_3_3_112_1","first-page":"282","article-title":"Regional cerebral blood flow, white matter abnormalities, and cerebrospinal fluid hydrodynamics in patients with idiopathic adult hydrocephalus syndrome.","volume":"60","author":"Kristensen B","year":"1996","unstructured":"Kristensen B , MalmJ, FagerlandMet al.: Regional cerebral blood flow, white matter abnormalities, and cerebrospinal fluid hydrodynamics in patients with idiopathic adult hydrocephalus syndrome.BMJ60(3) , 282\u2013288 (1996).","journal-title":"BMJ"},{"key":"e_1_3_3_3_113_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00175758"},{"key":"e_1_3_3_3_114_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.18.6.1074"},{"key":"e_1_3_3_3_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(85)90329-5"},{"key":"e_1_3_3_3_116_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1984.61.3.0510"},{"key":"e_1_3_3_3_117_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.66.3.0379"},{"issue":"6","key":"e_1_3_3_3_118_1","first-page":"697","article-title":"[Normal pressure hydrocephalus. Part 2. The evaluation of severity of cerebral dysfunction by measurement of \u201cbarrier ratio\u201d and regional cerebral blood flow (author's transl)].","volume":"30","author":"Baba M","year":"1978","unstructured":"Baba M , TakeyamaE, BeppuT, JimboM, KitamuraK: [Normal pressure hydrocephalus. Part 2. The evaluation of severity of cerebral dysfunction by measurement of \u201cbarrier ratio\u201d and regional cerebral blood flow (author's transl)].No To Shinkei30(6) , 697 (1978)).","journal-title":"No To Shinkei"},{"key":"e_1_3_3_3_119_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-200405000-00012"},{"key":"e_1_3_3_3_120_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.WCB.0000093326.88757.49"},{"key":"e_1_3_3_3_121_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2004.00325.x"},{"key":"e_1_3_3_3_122_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.47.299"},{"key":"e_1_3_3_3_123_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199610000-00023"},{"key":"e_1_3_3_3_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-3019(90)90243-I"},{"issue":"5","key":"e_1_3_3_3_125_1","first-page":"701","article-title":"Significance of periventricular hemodynamics in normal pressure hydrocephalus.","volume":"30","author":"Kimura M","year":"1992","unstructured":"Kimura M , TanakaA, YoshinagaS: Significance of periventricular hemodynamics in normal pressure hydrocephalus.Neurosurgery30(5) , 701 (1992).","journal-title":"Neurosurgery"},{"key":"e_1_3_3_3_126_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.1.96"},{"key":"e_1_3_3_3_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00717402"},{"key":"e_1_3_3_3_128_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01406498"},{"key":"e_1_3_3_3_129_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-199706000-00009"},{"issue":"11","key":"e_1_3_3_3_130_1","first-page":"1091","article-title":"Positron emission tomography with 18F fluorodeoxyglucose differentiates normal pressure hydrocephalus from Alzheimer-type dementia.","volume":"48","author":"Jagust W","year":"1985","unstructured":"Jagust W , FriedlandR, BudingerT: Positron emission tomography with 18F fluorodeoxyglucose differentiates normal pressure hydrocephalus from Alzheimer-type dementia.BMJ48(11) , 1091\u20131096 (1985).","journal-title":"BMJ"},{"key":"e_1_3_3_3_131_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.29.382"},{"key":"e_1_3_3_3_132_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh131"},{"key":"e_1_3_3_3_133_1","first-page":"39","article-title":"The role of cerebral blood flow and cerebrovascular reserve capacity in the diagnosis of chronic hydrocephalus \u2013 a PET-study on 60 patients.","volume":"81","author":"Klinge P","year":"2002","unstructured":"Klinge P , BerdingG, BrinkerTet al.: The role of cerebral blood flow and cerebrovascular reserve capacity in the diagnosis of chronic hydrocephalus \u2013 a PET-study on 60 patients.Acta Neurochir. Suppl.81, 39 (2002).","journal-title":"Acta Neurochir. Suppl."},{"key":"e_1_3_3_3_134_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.4.0605"},{"key":"e_1_3_3_3_135_1","first-page":"47","article-title":"Regional cerebral blood flow profiles of shunt-responder in idiopathic chronic hydrocephalus \u2013 a 15-O-water PET-study.","volume":"81","author":"Klinge P","year":"2002","unstructured":"Klinge P , BerdingG, BrinkerT, WeckesserE, KnappWH, SamiiM: Regional cerebral blood flow profiles of shunt-responder in idiopathic chronic hydrocephalus \u2013 a 15-O-water PET-study.Acta Neurochir. Suppl.81, 47\u201349 (2002).","journal-title":"Acta Neurochir. Suppl."},{"key":"e_1_3_3_3_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199884205"},{"key":"e_1_3_3_3_137_1","first-page":"43","article-title":"PET-studies in idiopathic chronic hydrocephalus before and after shunt-treatment: the role of risk factors for cerebrovascular disease (CVD) on cerebral hemodynamics.","volume":"81","author":"Klinge P","year":"2002","unstructured":"Klinge P , BerdingG, BrinkerT, SchuhmannM, KnappWH, SamiiM: PET-studies in idiopathic chronic hydrocephalus before and after shunt-treatment: the role of risk factors for cerebrovascular disease (CVD) on cerebral hemodynamics.Acta Neurochir. Suppl.81, 43 (2002).","journal-title":"Acta Neurochir. Suppl."},{"issue":"3","key":"e_1_3_3_3_138_1","first-page":"137","article-title":"Oxygen metabolism changes in patients with idiopathic normal pressure hydrocephalus before and after shunting operation.","volume":"116","author":"Miyamoto J","year":"2007","unstructured":"Miyamoto J , TatsuzawaK, InoueY, ImahoriY, MineuraK: Oxygen metabolism changes in patients with idiopathic normal pressure hydrocephalus before and after shunting operation.Mol. Microbiol.116(3) , 137 (2007).","journal-title":"Mol. Microbiol."},{"key":"e_1_3_3_3_139_1","doi-asserted-by":"publisher","DOI":"10.1179\/016164107X181851"},{"key":"e_1_3_3_3_140_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03033998"},{"key":"e_1_3_3_3_141_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-211-32318-X_36"},{"issue":"12","key":"e_1_3_3_3_142_1","first-page":"1884","article-title":"Postsurgical cerebral perfusion changes in idiopathic normal pressure hydrocephalus: a statistical parametric mapping study of SPECT images.","volume":"44","author":"Matar\u00f3 M","year":"2003","unstructured":"Matar\u00f3 M , PocaMA, Salgado-PinedaPet al.: Postsurgical cerebral perfusion changes in idiopathic normal pressure hydrocephalus: a statistical parametric mapping study of SPECT images.J. Nucl. Med.44(12) , 1884\u20131889 (2003).","journal-title":"J. Nucl. Med."},{"issue":"4","key":"e_1_3_3_3_143_1","first-page":"479","article-title":"Is a combination of Tc-SPECT or perfusion weighted magnetic resonance imaging with spinal tap test helpful in the diagnosis of normal pressure hydrocephalus?","volume":"74","author":"Hertel F","year":"2003","unstructured":"Hertel F , WalterC, SchmittMet al.: Is a combination of Tc-SPECT or perfusion weighted magnetic resonance imaging with spinal tap test helpful in the diagnosis of normal pressure hydrocephalus?BMJ74(4) , 479\u2013484 (2003).","journal-title":"BMJ"},{"key":"e_1_3_3_3_144_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.31.503"},{"key":"e_1_3_3_3_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007010200033"},{"key":"e_1_3_3_3_146_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mnm.0000170937.90958.22"},{"issue":"12","key":"e_1_3_3_3_147_1","first-page":"1589","article-title":"Regional cerebral blood flow in normal pressure hydrocephalus.","volume":"50","author":"Graff-Radford N","year":"1987","unstructured":"Graff-Radford N , RezaiK, GoderskyJ, EslingerP, DamasioH, KirchnerP: Regional cerebral blood flow in normal pressure hydrocephalus.BMJ50(12) , 1589\u20131596 (1987).","journal-title":"BMJ"},{"key":"e_1_3_3_3_148_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.12.1601"},{"key":"e_1_3_3_3_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01405132"},{"issue":"6","key":"e_1_3_3_3_150_1","first-page":"655","article-title":"High resolution SPECT with 99mTc-d, lHMPAO in normal pressure hydrocephalus before and after shunt operation.","volume":"56","author":"Waldemar G","year":"1993","unstructured":"Waldemar G , SchmidtJ, DelecluseF, AndersenA, GjerrisF, PaulsonO: High resolution SPECT with 99mTc-d, lHMPAO in normal pressure hydrocephalus before and after shunt operation.BMJ56(6) , 655\u2013664 (1993).","journal-title":"BMJ"},{"key":"e_1_3_3_3_151_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.39.841"},{"key":"e_1_3_3_3_152_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-007-1259-1"},{"key":"e_1_3_3_3_153_1","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2000.8.2.8"},{"key":"e_1_3_3_3_154_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-005-0891-z"},{"key":"e_1_3_3_3_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(03)00010-6"},{"key":"e_1_3_3_3_156_1","doi-asserted-by":"publisher","DOI":"10.1097\/RCT.0b013e31812f4edc"},{"key":"e_1_3_3_3_157_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.159.3.3704142"},{"key":"e_1_3_3_3_158_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.178.2.1987609"},{"key":"e_1_3_3_3_159_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-199701000-00015"},{"issue":"3","key":"e_1_3_3_3_160_1","first-page":"597","article-title":"Fast multiphase MR imaging of aqueductal CSF flow: 2. Study in patients with hydrocephalus.","volume":"11","author":"Mascalchi M","year":"1990","unstructured":"Mascalchi M : Fast multiphase MR imaging of aqueductal CSF flow: 2. Study in patients with hydrocephalus.AJNR Am. J. Neuroradiol.11(3) , 597\u2013603 (1990).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_161_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00588133"},{"key":"e_1_3_3_3_162_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841859309175413"},{"key":"e_1_3_3_3_163_1","doi-asserted-by":"publisher","DOI":"10.4065\/77.6.509"},{"key":"e_1_3_3_3_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300000376"},{"key":"e_1_3_3_3_165_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.198.2.8596861"},{"issue":"3","key":"e_1_3_3_3_166_1","first-page":"157","article-title":"Quantitative measurement of normal and hydrocephalic cerebrospinal fluid flow using phase contrast cine MR imaging.","volume":"47","author":"Katayama S","year":"1993","unstructured":"Katayama S , AsariS, OhmotoT: Quantitative measurement of normal and hydrocephalic cerebrospinal fluid flow using phase contrast cine MR imaging.Acta Med. Okayama47(3) , 157 (1993).","journal-title":"Acta Med. Okayama"},{"key":"e_1_3_3_3_167_1","first-page":"340","article-title":"Cine phase-contrast MR imaging in normal pressure hydrocephalus patients: relation to surgical outcome.","volume":"71","author":"Egeler-Peerdeman SM","year":"1998","unstructured":"Egeler-Peerdeman SM , BarkhofF, WalchenbachR, ValkJ: Cine phase-contrast MR imaging in normal pressure hydrocephalus patients: relation to surgical outcome.Acta Neurochir Suppl.71, 340\u2013342 (1998).","journal-title":"Acta Neurochir Suppl."},{"issue":"3","key":"e_1_3_3_3_168_1","first-page":"534","article-title":"Measurement of cerebrospinal fluid flow at the cerebral aqueduct by use of phase-contrast magnetic resonance imaging: technique validation and utility in diagnosing idiopathic normal pressure hydrocephalus.","volume":"50","author":"Luetmer P","year":"2002","unstructured":"Luetmer P , HustonJ, FriedmanJet al.: Measurement of cerebrospinal fluid flow at the cerebral aqueduct by use of phase-contrast magnetic resonance imaging: technique validation and utility in diagnosing idiopathic normal pressure hydrocephalus.Neurosurgery50(3) , 534 (2002).","journal-title":"Neurosurgery"},{"key":"e_1_3_3_3_169_1","first-page":"7","article-title":"Agreement between CSF flow dynamics in MRI and ICP monitoring in the diagnosis of normal pressure hydrocephalus. Sensitivity and specificity of CSF dynamics to predict outcome.","volume":"81","author":"Poca M","year":"2002","unstructured":"Poca M , SahuquilloJ, BustoMet al.: Agreement between CSF flow dynamics in MRI and ICP monitoring in the diagnosis of normal pressure hydrocephalus. Sensitivity and specificity of CSF dynamics to predict outcome.Acta Neurochir. Suppl.81, 7 (2002).","journal-title":"Acta Neurochir. Suppl."},{"key":"e_1_3_3_3_170_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003810050440"},{"key":"e_1_3_3_3_171_1","first-page":"191","article-title":"Normal and abnormal cerebrospinal fluid dynamics evaluated by optimized cine phase-contrast MR imaging.","volume":"25","author":"Chang LH","year":"2000","unstructured":"Chang LH , ChenCY, ChenMY, HuangTY, ChungHW: Normal and abnormal cerebrospinal fluid dynamics evaluated by optimized cine phase-contrast MR imaging.Zhonghua Fang She Xian Yi Xue Za Zhi25, 191\u2013195 (2000).","journal-title":"Zhonghua Fang She Xian Yi Xue Za Zhi"},{"issue":"1","key":"e_1_3_3_3_172_1","first-page":"13","article-title":"[Magnetic resonance imaging of aqueductal flow in patients with normal hydrocephalus pressure].","volume":"14","author":"Matias S","year":"2001","unstructured":"Matias S , FerreiraT, VilelaP, SeccaM, Goul\u00e3oA: [Magnetic resonance imaging of aqueductal flow in patients with normal hydrocephalus pressure].Acta Med. Port.14(1) , 13 (2001).","journal-title":"Acta Med. Port."},{"key":"e_1_3_3_3_173_1","first-page":"350","article-title":"Quantitative analysis of CSF flow dynamics using MRI in normal pressure hydrocephalus.","volume":"71","author":"Mase M","year":"1998","unstructured":"Mase M , YamadaK, BannoT, MiyachiT, OharaS, MatsumotoT: Quantitative analysis of CSF flow dynamics using MRI in normal pressure hydrocephalus.Acta Neurochir Suppl.71, 350\u2013353 (1998).","journal-title":"Acta Neurochir Suppl."},{"issue":"4","key":"e_1_3_3_3_174_1","first-page":"213","article-title":"[Assessment of reliable quantification of the dynamics of cerebrospinal fluid by magnetic resonance imaging in idiopathic normal pressure hydrocephalus]","volume":"22","author":"Forner J","year":"2007","unstructured":"Forner J , FlorezN,Valero Merino Cet al.: [Assessment of reliable quantification of the dynamics of cerebrospinal fluid by magnetic resonance imaging in idiopathic normal pressure hydrocephalus]. Neurologia22(4) , 213 (2007)","journal-title":"Neurologia"},{"key":"e_1_3_3_3_175_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00115-006-2231-7"},{"key":"e_1_3_3_3_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-3019(97)00032-3"},{"key":"e_1_3_3_3_177_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-005-1418-0"},{"key":"e_1_3_3_3_178_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000315864.26706.9A"},{"key":"e_1_3_3_3_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2007.12.021"},{"key":"e_1_3_3_3_180_1","doi-asserted-by":"publisher","DOI":"10.6009\/jjrt.62.63"},{"key":"e_1_3_3_3_181_1","doi-asserted-by":"publisher","DOI":"10.1007\/3-211-32318-X_62"},{"key":"e_1_3_3_3_182_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20999"},{"key":"e_1_3_3_3_183_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-002-0901-0"},{"key":"e_1_3_3_3_184_1","doi-asserted-by":"publisher","DOI":"10.1080\/02841859609173439"},{"issue":"8","key":"e_1_3_3_3_185_1","first-page":"1717","article-title":"Diffusion tensor imaging in hydrocephalus: initial experience.","volume":"27","author":"Assaf Y","year":"2006","unstructured":"Assaf Y , Ben-SiraL, ConstantiniS, ChangL, Beni-AdaniL: Diffusion tensor imaging in hydrocephalus: initial experience.AJNR Am. J. Neuroradiol.27(8) , 1717 (2006).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(08)70016-7"},{"issue":"9","key":"e_1_3_3_3_187_1","first-page":"1659","article-title":"Proton chemical shift imaging in normal pressure hydrocephalus.","volume":"22","author":"Kizu O","year":"2001","unstructured":"Kizu O , YamadaK, NishimuraT: Proton chemical shift imaging in normal pressure hydrocephalus.AJNR Am. J. Neuroradiol.22(9) , 1659\u20131664 (2001).","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"e_1_3_3_3_188_1","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2000.11741038"},{"key":"e_1_3_3_3_189_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10270"},{"issue":"8","key":"e_1_3_3_3_190_1","first-page":"1141","article-title":"Magnetic resonance spectroscopic determination of a neuronal and axonal marker in white matter predicts reversibility of deficits in secondary normal pressure hydrocephalus.","volume":"75","author":"Shiino A","year":"2004","unstructured":"Shiino A , NishidaY, YasudaH, SuzukiM, MatsudaM, InubushiT: Magnetic resonance spectroscopic determination of a neuronal and axonal marker in white matter predicts reversibility of deficits in secondary normal pressure hydrocephalus.BMJ75(8) , 1141\u20131148 (2004).","journal-title":"BMJ"},{"issue":"7","key":"e_1_3_3_3_191_1","first-page":"760","article-title":"Post-surgical changes in brain metabolism detected by magnetic resonance spectroscopy in normal pressure hydrocephalus: results of a pilot study.","volume":"78","author":"del Mar Matar\u00edn M","year":"2007","unstructured":"del Mar Matar\u00edn M , PueyoR, PocaMet al.: Post-surgical changes in brain metabolism detected by magnetic resonance spectroscopy in normal pressure hydrocephalus: results of a pilot study.BMJ78(7) , 760\u2013763 (2007).","journal-title":"BMJ"},{"key":"e_1_3_3_3_192_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1130"},{"issue":"6","key":"e_1_3_3_3_193_1","first-page":"201","article-title":"Recognition of gait disturbances in patients with normal pressure hydrocephalus using a computer dynography system.","volume":"59","author":"Czerwosz L","year":"2008","unstructured":"Czerwosz L , SzczepekE, SokolowskaBet al.: Recognition of gait disturbances in patients with normal pressure hydrocephalus using a computer dynography system.J. Physiol. Pharmacol.59(6) , 201\u2013207 (2008).","journal-title":"J. Physiol. Pharmacol."},{"key":"e_1_3_3_3_194_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2008.02.003"},{"issue":"3","key":"e_1_3_3_3_195_1","first-page":"289","article-title":"Comparative analysis of the gait disorder of normal pressure hydrocephalus and Parkinson's disease.","volume":"70","author":"Stolze H","year":"2001","unstructured":"Stolze H , Kuhtz-BuschbeckJP, DruckeH, JohnkK, IllertM, DeuschlG: Comparative analysis of the gait disorder of normal pressure hydrocephalus and Parkinson's disease.BMJ70(3) , 289\u2013297 (2001).","journal-title":"BMJ"},{"key":"e_1_3_3_3_196_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHM.0b013e31815b6461"},{"key":"e_1_3_3_3_197_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0404.2000.102005284.x"},{"key":"e_1_3_3_3_198_1","unstructured":"Seaton BL : Verification of Molecular assays. In: Molecular Diagnostics: for the Clinical Laboratorian (2nd Edition). Coleman WB Tsongalis GJ (Eds). Humana Press Inc. Totowa NJ USA (2006)."},{"key":"e_1_3_3_3_199_1","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8454-5-19"},{"key":"e_1_3_3_3_200_1","article-title":"Asymptomatic ventriculomegaly with features of idiopathic normal pressure hydrocephalus on MRI (AVIM) in the elderly: a prospective study in a Japanese population.","author":"Iseki C","year":"2008","unstructured":"Iseki C , KawanamiT, NagasawaHet al.: Asymptomatic ventriculomegaly with features of idiopathic normal pressure hydrocephalus on MRI (AVIM) in the elderly: a prospective study in a Japanese population.J. Neurol. Sci. (2008).","journal-title":"J. Neurol. Sci."}],"container-title":["Biomarkers in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/bmm.09.37","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T06:35:51Z","timestamp":1719124551000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/bmm.09.37"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":200,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,12]]}},"alternative-id":["10.2217\/bmm.09.37"],"URL":"https:\/\/doi.org\/10.2217\/bmm.09.37","relation":{},"ISSN":["1752-0363","1752-0371"],"issn-type":[{"value":"1752-0363","type":"print"},{"value":"1752-0371","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}