{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T12:06:12Z","timestamp":1784117172634,"version":"3.55.0"},"reference-count":33,"publisher":"Becaris Publishing Limited","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Comp. Eff. Res."],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p><jats:bold>Aim:<\/jats:bold>This study evaluated the occurrence and associated costs of pacemaker complications in Germany from 2010 to 2013.<jats:bold>Patients &amp; methods:<\/jats:bold>Patients with a<jats:italic>de novo<\/jats:italic>or replacement implantation of a single or dual chamber pacemaker between 2010 and 2013 were followed for 12\u00a0months post-implant using German health insurance claims data. A case\u2013control analysis was performed using propensity score matching to estimate the costs of complications.<jats:bold>Results:<\/jats:bold>Out of 12,922 implanted patients, 12.0% had a complication in the year following the implant. Complications related to lead and pocket were found in 10.2% of all implanted patients; infections occurred in 1.7% patients. Healthcare costs up to 36\u00a0months post complication were on average \u20ac4627 higher than for pacemaker patients without a complication.<jats:bold>Conclusion:<\/jats:bold>Pacemaker complications are common and represent a burden for patients and healthcare systems generating substantial costs. Most of the pacemaker complications involved the pacing lead or pacemaker pocket.<\/jats:p>","DOI":"10.2217\/cer-2018-0114","type":"journal-article","created":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T09:19:47Z","timestamp":1558084787000},"page":"589-597","source":"Crossref","is-referenced-by-count":17,"title":["Complications and associated healthcare costs of transvenous cardiac pacemakers in Germany"],"prefix":"10.57264","volume":"8","author":[{"given":"Saskia","family":"Ludwig","sequence":"first","affiliation":[{"name":"HGC GesundheitsConsult GmbH, M\u00f6rsenbroicher Weg 200, 40470 Duesseldorf, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathrin","family":"Theis","sequence":"additional","affiliation":[{"name":"Robert-Bosch-Krankenhaus, Zentrum f\u00fcr Innere Medizin III Kardiologie, Auerbachstra\u00dfe 110, 70376 Stuttgart, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5570-6137","authenticated-orcid":false,"given":"Claudia","family":"Wolff","sequence":"additional","affiliation":[{"name":"Medtronic International Trading S\u00e0rl, Route du Molliau 31, 1131 Tolochenaz, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7357-5620","authenticated-orcid":false,"given":"Emmanuelle","family":"Nicolle","sequence":"additional","affiliation":[{"name":"Medtronic International Trading S\u00e0rl, Route du Molliau 31, 1131 Tolochenaz, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Witthohn","sequence":"additional","affiliation":[{"name":"Medtronic GmbH, Earl-Bakken-Platz 1, 40670 Meerbusch, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"G\u00f6tte","sequence":"additional","affiliation":[{"name":"St. Vincenz Hospital Paderborn, Dept of Cardiology &amp; Intensive Care Medicine, Am Busdorf 2, 33098 Paderborn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36897","reference":[{"issue":"8","key":"e_1_3_4_3_2","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1093\/europace\/eut206","article-title":"2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy: the task force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). 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Cardiol. 227, 122\u2013126 (2017).","journal-title":"Int. J. Cardiol."},{"key":"e_1_3_4_35_2","doi-asserted-by":"crossref","DOI":"10.1111\/jce.13851","article-title":"Leadless pacemaker implant in patients with pre-existing infections: results from the micra post-approval registry","author":"El Chami MF","year":"2019","unstructured":"El Chami MF , Brock Johansen J , Zaidi A Leadless pacemaker implant in patients with pre-existing infections: results from the micra post-approval registry. J. Cardiovasc. Electrophysiol. doi:10.1111\/jce.13851 (2019) (Epub ahead of print).","journal-title":"J. Cardiovasc. 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