{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T04:03:00Z","timestamp":1788321780038,"version":"build-2803163510"},"reference-count":18,"publisher":"Becaris Publishing Limited","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Comp. Eff. Res."],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>\n            <jats:bold>Aim:<\/jats:bold>\n            To estimate rates of fracture-related infection (FRI) and nonunion and assess the healthcare burden associated with FRI among patients with open reduction and internal fixation (ORIF) for Type III open tibial shaft fractures (TSFs).\n            <jats:bold>Methods:<\/jats:bold>\n            Patients with type III TSF requiring ORIF were identified using MarketScan\n            <jats:sup>\u00ae<\/jats:sup>\n            Database. Healthcare utilization and total costs were compared using generalized linear models.\n            <jats:bold>Results:<\/jats:bold>\n            The rates of FRI and nonunion were 35.99 and 36.94%, respectively, at 365 days. Patients with FRI had a significantly higher rate of readmission, emergency room visit and total healthcare costs compared with patients without FRI.\n            <jats:bold>Conclusion:<\/jats:bold>\n            Patients with an ORIF procedure for Type III TSF have a high risk of FRI and nonunion and; FRI significantly increased the healthcare burden.\n          <\/jats:p>","DOI":"10.2217\/cer-2019-0040","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T10:28:59Z","timestamp":1559903339000},"page":"907-915","source":"Crossref","is-referenced-by-count":5,"title":["Complications in type III open tibial shaft fractures treated with open reduction and internal fixation"],"prefix":"10.57264","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4334-4001","authenticated-orcid":false,"given":"Abhishek S","family":"Chitnis","sequence":"first","affiliation":[{"name":"Medical Devices Epidemiology, Real World Data Sciences, Johnson &amp; Johnson, New Brunswick, NJ 08901, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mollie","family":"Vanderkarr","sequence":"additional","affiliation":[{"name":"Health Economics Market Access, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charisse","family":"Sparks","sequence":"additional","affiliation":[{"name":"Medical Affairs, DePuy Synthes Orthopaedics, West Chester, PA 19380, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"McGlohorn","sequence":"additional","affiliation":[{"name":"Clinical Research, DePuy Synthes Switzerland, Solothurn 4528, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal E","family":"Holy","sequence":"additional","affiliation":[{"name":"Medical Devices Epidemiology, Real World Data Sciences, Johnson &amp; Johnson, New Brunswick, NJ 08901, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36897","reference":[{"issue":"3","key":"e_1_3_4_3_2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1302\/0301-620X.88B3.16465","article-title":"A review of the management of open fractures of the tibia and femur","volume":"88","author":"Giannoudis PV","year":"2006","unstructured":"Giannoudis PV , Papakostidis C , Roberts C . 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