{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T10:53:16Z","timestamp":1782816796331,"version":"3.54.5"},"reference-count":59,"publisher":"Becaris Publishing Limited","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Comp. Eff. Res."],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>\n            <jats:bold>Aim:<\/jats:bold>\n            To perform cost\u2013effectiveness analysis (CEA) and budget impact analysis (BIA) comparing stenting to standard medical treatment (SMT) for the management of deep venous outflow obstruction and leg ulcers from the Italian Healthcare Service perspective.\n            <jats:bold>Materials &amp; methods:<\/jats:bold>\n            A Markov model was developed to project costs and quality-adjusted life-years (QALYs)\u00a0over 3 years, based on data from literature combined with real-world data. Moreover, a BIA was performed comparing the current scenario (100% SMT) with increasing utilization rates of stenting over SMT from 0.5 to 5%, in the next 5 years.\n            <jats:bold>Results:<\/jats:bold>\n            Stenting is a cost-effective (incremental cost-utility ratio \u20ac12,388\/QALY) or dominant option versus SMT, according to in-patient or day-hospital settings, respectively. Increasing use of stenting over SMT, in the next 5\u00a0years, is expected to yield additional costs of 39.5\u00a0million Euros (in-patient) or savings of 5.1\u00a0million Euros (day-hospital).\n            <jats:bold>Conclusion:<\/jats:bold>\n            Stenting is a cost-effective option compared with SMT for patients with deep vein occlusion and ulceration in Italy.\n          <\/jats:p>","DOI":"10.2217\/cer-2020-0030","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T10:45:22Z","timestamp":1595241922000},"page":"705-720","source":"Crossref","is-referenced-by-count":14,"title":["Venous stenting for patients with outflow obstruction and leg ulcers: cost\u2013effectiveness and budget impact analyses"],"prefix":"10.57264","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6330-0591","authenticated-orcid":false,"given":"Carla","family":"Rognoni","sequence":"first","affiliation":[{"name":"Centre for Research on Health and Social Care Management (CERGAS), SDA Bocconi School of Management, Bocconi University, Milan\u00a020136, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzia","family":"Lugli","sequence":"additional","affiliation":[{"name":"National Reference Training Center in Phlebology (NRTCP), Vascular Surgery \u2013 Cardiovascular Deptartment, Hesperia Hospital, Modena\u00a041125, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Maleti","sequence":"additional","affiliation":[{"name":"National Reference Training Center in Phlebology (NRTCP), Vascular Surgery \u2013 Cardiovascular Deptartment, Hesperia Hospital, Modena\u00a041125, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosanna","family":"Tarricone","sequence":"additional","affiliation":[{"name":"Centre for Research on Health and Social Care Management (CERGAS), SDA Bocconi School of Management, Bocconi University, Milan\u00a020136, Italy"},{"name":"Department of Social and Political Sciences, Bocconi University, Milan 20136, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36897","reference":[{"issue":"3","key":"e_1_3_5_3_2","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1067\/mjd.2002.121739","article-title":"Venous leg ulcer: incidence and prevalence in the elderly","volume":"46","author":"Margolis DJ","year":"2002","unstructured":"Margolis DJ, Bilker W, Santanna J, Baumgarten M. 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