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Res."],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p><jats:bold>Aim:<\/jats:bold>To estimate the economic impacts of increased use of specialty care infusion centers for treating adults experiencing vaso-occlusive crises.<jats:bold>Methods:<\/jats:bold>A\u00a0Markov model is developed\u00a0to estimate the\u00a0impact of expanding use of specialty care infusion centers to treat vaso-occlusive crises compared to emergency department care.<jats:bold>Results:<\/jats:bold>Access to infusion centers for sickle cell disease could result in savings over US$1.9\u00a0billion in formal medical costs and over US$2\u00a0billion in societal costs, based on uptake assumptions over 10\u00a0years.<jats:bold>Conclusion:<\/jats:bold>Expansion of adult sickle cell disease centers across the nation could lead to considerably better economic outcomes in the form of reduced costs and hospital length of stay in addition to improved clinical outcomes as reported in the existing literature.<\/jats:p>","DOI":"10.2217\/cer-2021-0257","type":"journal-article","created":{"date-parts":[[2022,2,21]],"date-time":"2022-02-21T11:43:30Z","timestamp":1645443810000},"page":"399-409","source":"Crossref","is-referenced-by-count":6,"title":["An impact evaluation of two modes of care for sickle cell disease crises"],"prefix":"10.57264","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0195-2121","authenticated-orcid":false,"given":"Robert","family":"Skinner","sequence":"first","affiliation":[{"name":"Insight Policy Research, Arlington, VA\u00a022209, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0950-5796","authenticated-orcid":false,"given":"Andrew","family":"Breck","sequence":"additional","affiliation":[{"name":"Insight Policy Research, Arlington, VA\u00a022209, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2995-9736","authenticated-orcid":false,"given":"Dominick","family":"Esposito","sequence":"additional","affiliation":[{"name":"Insight Policy Research, Arlington, VA\u00a022209, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"36897","reference":[{"issue":"5","key":"e_1_3_4_3_2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1111\/j.1553-2712.2007.tb01801.x","article-title":"Emergency department management of acute pain episodes in sickle cell disease","volume":"14","author":"Tanabe P","year":"2008","unstructured":"Tanabe P, Myers R, Zosel A Emergency department management of acute pain episodes in sickle cell disease. 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