{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T22:21:51Z","timestamp":1765232511574},"reference-count":61,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Epigenomics"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.2217\/epi-2017-0081","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T10:51:59Z","timestamp":1511952719000},"page":"105-113","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":15,"title":["Evaluating LINE-1 Methylation in Cleft Lip Tissues and its Association with Early Pregnancy Exposures"],"prefix":"10.1080","volume":"10","author":[{"given":"Mohammad Faisal J","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Biomedical&Specialty Surgical Sciences, Section of Medical Biochemistry, Molecular Biology&Genetics, University of Ferrara, Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Little","sequence":"additional","affiliation":[{"name":"School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter A","family":"Mossey","sequence":"additional","affiliation":[{"name":"Craniofacial Development at the WHO-collaborating Centre for Oral&Craniofacial Research, Dental Hospital&School, University of Dundee, Dundee, Scotland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9gine PM","family":"Steegers-Theunissen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics&Gynaecology, Department of Pediatrics, Division Neonatology Erasmus MC, University Medical Center, Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Autelitano","sequence":"additional","affiliation":[{"name":"Department of Cranio-Maxillo-Facial Surgery, Regional Centre for Orofacial Clefts&Craniofacial Anomalies, San Paolo Hospital, University of Milan, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilenia","family":"Lombardo","sequence":"additional","affiliation":[{"name":"Department of Biomedical&Specialty Surgical Sciences, Section of Medical Biochemistry, Molecular Biology&Genetics, University of Ferrara, Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita Bassi","family":"Andreasi","sequence":"additional","affiliation":[{"name":"Department of Biomedical&Specialty Surgical Sciences, Section of Medical Biochemistry, Molecular Biology&Genetics, University of Ferrara, Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Rubini","sequence":"additional","affiliation":[{"name":"Department of Biomedical&Specialty Surgical Sciences, Section of Medical Biochemistry, Molecular Biology&Genetics, University of Ferrara, Ferrara, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2017,11,29]]},"reference":[{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genom-090711-163729"},{"key":"e_1_3_3_4_1","first-page":"106","article-title":"Incidence of cleft lip and palate: constant or increasing?","volume":"122","author":"Fogh-Andersen P","year":"1961","unstructured":"Fogh-Andersen P . Incidence of cleft lip and palate: constant or increasing?Acta. Chir. Scand.122 , 106 \u2013 111 ( 1961 ).","journal-title":"Acta. Chir. Scand."},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780195139068.003.0012"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2933"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2011.07.007"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2015.13"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030153"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1079\/PHN2001145"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu7010153"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2014.08.003"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2015.07.011"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.113.080655"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-0004.2002.610402.x"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000322486"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.15171\/joddd.2015.020"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyn098"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23133"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-013-9849-0"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0083-6729(08)00401-9"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707258104"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-017-0321-y"},{"issue":"10","key":"e_1_3_3_24_1","first-page":"3462","article-title":"In utero supplementation with methyl donors enhances allergic airway disease in mice","volume":"118","author":"Hollingsworth JW","year":"2008","unstructured":"Hollingsworth JW , MaruokaS , BoonKet al. In utero supplementation with methyl donors enhances allergic airway disease in mice . J. Clin. Invest.118 ( 10 ), 3462 \u2013 3469 ( 2008 ).","journal-title":"J. Clin. Invest."},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1610259113"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.6.5.705"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2003.1326"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.4.6.9766"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gnh032"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-016-0247-9"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2011.649931"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078462"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.2009.28858"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-017-0357-z"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-017-1106-1"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn359"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23320"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2015.10.009"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.2217\/epi.13.1"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2013.12.003"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0070-2153(08)00602-9"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1159\/000337523"},{"key":"e_1_3_3_43_1","first-page":"94502","volume-title":"Review Of Medical Embryology","author":"Pansky B","year":"1982","unstructured":"Pansky B . Review Of Medical Embryology . Embryome Sciences, Inc 1301 Harbor Bay Parkway , CA, USA , 94502 ( 1982 )."},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-017-0362-2"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02721-0"},{"key":"e_1_3_3_46_1","unstructured":"University of Ferrara projects\n . www.unife.it\/progetto\/pentacleft ."},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-016-0227-0"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gnh032"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-12-12"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80337-5"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.316.7139.1236"},{"issue":"5","key":"e_1_3_3_52_1","first-page":"502","article-title":"When to use the Bonferroni correction. Ophthalmic&physiological optics: the journal of the British College of Ophthalmic","volume":"34","author":"Armstrong RA","year":"2014","unstructured":"Armstrong RA . When to use the Bonferroni correction. Ophthalmic&physiological optics: the journal of the British College of Ophthalmic . Opticians34 ( 5 ), 502 \u2013 508 ( 2014 ).","journal-title":"Opticians"},{"issue":"11","key":"e_1_3_3_53_1","first-page":"2082","article-title":"Sonic Hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis","volume":"144","author":"Everson JL","year":"2017","unstructured":"Everson JL , FinkDM , YoonJWet al. Sonic Hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis . Development144 ( 11 ), 2082 \u2013 2091 ( 2017 ).","journal-title":"Development"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0121869"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1080\/15592294.2014.998536"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-12-31"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.23529"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022126"},{"issue":"1","key":"e_1_3_3_59_1","first-page":"41","article-title":"Nutrition during pregnancy impacts offspring\u2019s epigenetic status-evidence from human and animal studies","volume":"8","author":"Geraghty AA","year":"2015","unstructured":"Geraghty AA , LindsayKL , AlberdiG , McAuliffeFM , GibneyER . Nutrition during pregnancy impacts offspring\u2019s epigenetic status-evidence from human and animal studies . Nutr. Metab. Insights8 ( Suppl. 1 ), 41 \u2013 47 ( 2015 ).","journal-title":"Nutr. Metab. Insights"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1597\/14-306"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016252"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.6.5.15335"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208137"}],"container-title":["Epigenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/epi-2017-0081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T22:52:14Z","timestamp":1715986334000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/epi-2017-0081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,29]]},"references-count":61,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.2217\/epi-2017-0081"],"URL":"https:\/\/doi.org\/10.2217\/epi-2017-0081","relation":{},"ISSN":["1750-1911","1750-192X"],"issn-type":[{"value":"1750-1911","type":"print"},{"value":"1750-192X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}