{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:07:41Z","timestamp":1790622461542,"version":"4.1.0"},"reference-count":97,"publisher":"Informa UK Limited","issue":"15","funder":[{"name":"Veteran Affairs","award":["VA Merit grant I01BX002876"],"award-info":[{"award-number":["VA Merit grant I01BX002876"]}]},{"name":"National Institute Health","award":["NIH\/NIMH U01MH116442"],"award-info":[{"award-number":["NIH\/NIMH U01MH116442"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Epigenomics"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.2217\/epi-2021-0077","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T15:25:46Z","timestamp":1627572346000},"page":"1157-1169","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["DNA Methylation Differences in Cortical Grey and White Matter in Schizophrenia"],"prefix":"10.1080","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7546-0250","authenticated-orcid":false,"given":"Amber","family":"Berdenis van Berlekom","sequence":"first","affiliation":[{"name":"Department of Translational Neuroscience, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Notman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjolein AM","family":"Sneeboer","sequence":"additional","affiliation":[{"name":"Department of Translational Neuroscience, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2694-1234","authenticated-orcid":false,"given":"Gijsje JLJ","family":"Snijders","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lotte C","family":"Houtepen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny M","family":"Nispeling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"He","sequence":"additional","affiliation":[{"name":"Department of Translational Neuroscience, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5917-8688","authenticated-orcid":false,"given":"Stella","family":"Dracheva","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA"},{"name":"Mental Illness Research, Education,&amp;Clinical Center (VISN 2 South), James J Peters VA Medical Center, Bronx, NY10468, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elly M","family":"Hol","sequence":"additional","affiliation":[{"name":"Department of Translational Neuroscience, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9 S","family":"Kahn","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA"},{"name":"Mental Illness Research, Education,&amp;Clinical Center (VISN 2 South), James J Peters VA Medical Center, Bronx, NY10468, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lot D","family":"de Witte","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY10029, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6163-7484","authenticated-orcid":false,"given":"Marco P","family":"Boks","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Brain Center University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Psychiatric Donor Program of the Netherlands Brain Bank (NBB-PSY)","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,7,29]]},"reference":[{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2011.01.032"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.157.1.16"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.105.015701"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs118"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.05.021"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22075"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2000.2.4\/pharrison"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1986.01800010038005"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001337"},{"key":"e_1_3_6_12_1","first-page":"1","article-title":"Network modules linking expression and methylation in prefrontal cortex of schizophrenia","volume":"20","author":"Lin D","year":"2020","unstructured":"Lin D , ChenJ , DuanKet al. Network modules linking expression and methylation in prefrontal cortex of schizophrenia. Epigenetic.20, 1\u201318 (2020).","journal-title":"Epigenetic."},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2019.21.4\/sakbarian"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0006767"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2013.03.020"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2012.04.002"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0483-2"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp104"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-13-636"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0601-3"},{"issue":"7","key":"e_1_3_6_21_1","first-page":"1496","article-title":"Epigenetics in schizophrenia: a pilot study of global dna methylation in different brain regions associated with higher cognitive functions","volume":"30","author":"Alel\u00fa-Paz R","year":"2016","unstructured":"Alel\u00fa-Paz R , CarmonaFJ , Sanchez-MutJVet al. Epigenetics in schizophrenia: a pilot study of global dna methylation in different brain regions associated with higher cognitive functions. Front. Psychol.30(7), 1496 (2016).","journal-title":"Front. Psychol."},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12255"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12920-015-0139-4"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4181"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2008.01.008"},{"issue":"5","key":"e_1_3_6_26_1","first-page":"280 (","article-title":"DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia","volume":"26","author":"Numata S","year":"2014","unstructured":"Numata S , YeT , HermanM , LipskaBK. DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia. Front. Genet.26(5), 280 (2014).","journal-title":"Front. Genet."},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0483-2"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbv182"},{"issue":"1","key":"e_1_3_6_29_1","first-page":"210","article-title":"Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions","volume":"26","author":"Viana J","year":"2017","unstructured":"Viana J , HannonE , DempsterEet al. Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Hum. Mol. Genet.26(1), 210\u2013225 (2017).","journal-title":"Hum. Mol. Genet."},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2013.111"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.177"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2012-13-6-r43"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.23924"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.5.6.12228"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.21959"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2009.09.001"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1222897110"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.116"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.03.031"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.07101562"},{"key":"e_1_3_6_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-017-1513-x"},{"key":"e_1_3_6_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2247"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-11-587"},{"key":"e_1_3_6_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty476"},{"key":"e_1_3_6_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0503-2"},{"issue":"4","key":"e_1_3_6_46_1","first-page":"e22","article-title":"Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes","volume":"45","author":"Zhou W","year":"2017","unstructured":"Zhou W , LairdPW , ShenH. Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes. Nucleic Acids Res.45(4), e22 (2017).","journal-title":"Nucleic Acids Res."},{"key":"e_1_3_6_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-016-1066-1"},{"key":"e_1_3_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gdata.2016.05.012"},{"key":"e_1_3_6_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr171"},{"key":"e_1_3_6_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780090710"},{"key":"e_1_3_6_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-8935-8-6"},{"issue":"91","key":"e_1_3_6_52_1","first-page":"3","article-title":"Statistical decision from k test series with particular focus on population genetics tools: a DIY notice","volume":"22","author":"De Mee\u00fbs T","year":"2014","unstructured":"De Mee\u00fbs T . Statistical decision from k test series with particular focus on population genetics tools: a DIY notice. Infect. Genet. Evol.22(91), 3 (2014).","journal-title":"Infect. Genet. Evol."},{"key":"e_1_3_6_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.23023"},{"key":"e_1_3_6_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2004.10.002"},{"key":"e_1_3_6_55_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260419"},{"key":"e_1_3_6_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-019-0490-x"},{"key":"e_1_3_6_57_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2260-09.2009"},{"key":"e_1_3_6_58_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0643-16.2017"},{"key":"e_1_3_6_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2017.10.025"},{"key":"e_1_3_6_60_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119853109"},{"key":"e_1_3_6_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2012.03.007"},{"key":"e_1_3_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2012.08.008"},{"key":"e_1_3_6_63_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.873001"},{"key":"e_1_3_6_64_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat9528"},{"key":"e_1_3_6_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/S10059-012-2284-3"},{"key":"e_1_3_6_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2014.11.005"},{"key":"e_1_3_6_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2017.05.003"},{"key":"e_1_3_6_68_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.20.2181"},{"key":"e_1_3_6_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.11.006"},{"key":"e_1_3_6_70_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291717000022"},{"key":"e_1_3_6_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2016.232"},{"key":"e_1_3_6_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-004-0725-6"},{"key":"e_1_3_6_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2016.07.005"},{"key":"e_1_3_6_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.12.229"},{"key":"e_1_3_6_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.07.092"},{"key":"e_1_3_6_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.07.007"},{"key":"e_1_3_6_77_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200211087"},{"key":"e_1_3_6_78_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aat8127"},{"key":"e_1_3_6_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1001-160"},{"key":"e_1_3_6_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-9081-9-9"},{"key":"e_1_3_6_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.886"},{"key":"e_1_3_6_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0059-2"},{"key":"e_1_3_6_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13595"},{"key":"e_1_3_6_84_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.58430"},{"key":"e_1_3_6_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1001-166"},{"key":"e_1_3_6_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-011-0242-2"},{"key":"e_1_3_6_87_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn176"},{"key":"e_1_3_6_88_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.1328"},{"key":"e_1_3_6_89_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003329171300024X"},{"key":"e_1_3_6_90_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2013.00169"},{"issue":"2","key":"e_1_3_6_91_1","first-page":"89","article-title":"Schizophrenia: a disconnection syndrome?","volume":"3","author":"Friston KJ","year":"1995","unstructured":"Friston KJ , FrithCD. Schizophrenia: a disconnection syndrome?Clin. Neurosci.3(2), 89\u201397 (1995).","journal-title":"Clin. Neurosci."},{"key":"e_1_3_6_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2010.09.004"},{"issue":"2","key":"e_1_3_6_93_1","first-page":"374","article-title":"Synapse pathology in schizophrenia: a meta-analysis of postsynaptic elements in postmortem brain studies","volume":"46","author":"Berdenis Van Berlekom A","year":"2020","unstructured":"Berdenis Van Berlekom A , MuflihahCH , SnijdersGJLJet al. Synapse pathology in schizophrenia: a meta-analysis of postsynaptic elements in postmortem brain studies. Schizophr. Bull.46(2), 374\u2013386 (2020).","journal-title":"Schizophr. Bull."},{"key":"e_1_3_6_94_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.1.65"},{"key":"e_1_3_6_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2012.04.044"},{"key":"e_1_3_6_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-018-0041-5"},{"key":"e_1_3_6_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30302-5"},{"key":"e_1_3_6_98_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.21959"},{"key":"e_1_3_6_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3405"}],"container-title":["Epigenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/epi-2021-0077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T09:38:05Z","timestamp":1715938685000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/epi-2021-0077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,29]]},"references-count":97,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.2217\/epi-2021-0077"],"URL":"https:\/\/doi.org\/10.2217\/epi-2021-0077","relation":{},"ISSN":["1750-1911","1750-192X"],"issn-type":[{"value":"1750-1911","type":"print"},{"value":"1750-192X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}