{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:47:40Z","timestamp":1792802860646,"version":"4.5.0"},"reference-count":39,"publisher":"Informa UK Limited","issue":"12","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Incubating Program for Clinical Research and Innovation of Renji Hospital","award":["PYXJS16-008, PYIII20-07"],"award-info":[{"award-number":["PYXJS16-008, PYIII20-07"]}]},{"name":"Shanghai Science and Technology Commission Research Project","award":["21ZR1438900"],"award-info":[{"award-number":["21ZR1438900"]}]},{"name":"Basic Oncology Research Program from Bethune Charitable Foundation","award":["BCF-NH-ZL-20201119-024"],"award-info":[{"award-number":["BCF-NH-ZL-20201119-024"]}],"id":[{"id":"https:\/\/ror.org\/0430c7a41","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Oncol."],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.2217\/fon-2021-1267","type":"journal-article","created":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T09:18:43Z","timestamp":1643707123000},"page":"1461-1471","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":5,"title":["Second-Line Treatment with Axitinib Plus Toripalimab in Metastatic Renal Cell Carcinoma: A Retrospective Multicenter Study"],"prefix":"10.1080","volume":"18","author":[{"given":"Jiwei","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guohai","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Urology, Fudan University Shanghai Cancer Center,  \rShanghai, 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine,  \rHangzhou, 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Kong","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiran","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Urology, First Affiliated Hospital, Zhejiang University School of Medicine,  \rHangzhou, 310003, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Urology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University,  \rShanghai, 200127, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,2]]},"reference":[{"key":"e_1_3_5_3_1","unstructured":"American Cancer Society . What is kidney cancer?www.cancer.org\/cancer\/kidney-cancer\/about\/what-is-kidney-cancer.html"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.09.002"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61613-9"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00221"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/835680"},{"issue":"9","key":"e_1_3_5_8_1","first-page":"1046","article-title":"[Combination of targeted therapy and immunotherapy for cancer]","volume":"42","author":"Kadowaki N","year":"2015","unstructured":"Kadowaki N . [Combination of targeted therapy and immunotherapy for cancer]. Gan To Kagaku Ryoho.42(9), 1046\u20131049 (2015).","journal-title":"Gan To Kagaku Ryoho."},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-0153"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3237"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.8167"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-1993"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.05-4493com"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12069"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.15_suppl.4504"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2020.12.009"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30081-0"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.36.15_suppl.4560"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.15_suppl.4505"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2016.161"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2019.1596513"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70093-7"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-020-01708-8"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.12868"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0184423"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00290-9"},{"key":"e_1_3_5_27_1","unstructured":"National Cancer Institute: Cancer Therapy Evaluation Program . Common Terminology Criteria for Adverse Events (CTCAE): protocol development. https:\/\/ctep.cancer.gov\/protocoldevelopment\/electronic_applications\/ctc.htm"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.10.026"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70559-4"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-016-3016-4"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.7395"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2020.04.010"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1712126"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(16)30107-3"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33033"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.2535"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2019.10.032"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816714"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30436-8"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.14294"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2016.06.019"}],"container-title":["Future Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/fon-2021-1267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T02:43:26Z","timestamp":1719110606000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/fon-2021-1267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":39,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.2217\/fon-2021-1267"],"URL":"https:\/\/doi.org\/10.2217\/fon-2021-1267","relation":{},"ISSN":["1479-6694","1744-8301"],"issn-type":[{"value":"1479-6694","type":"print"},{"value":"1744-8301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-10-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}