{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T18:54:39Z","timestamp":1789239279745,"version":"build-2803163510"},"reference-count":66,"publisher":"Informa UK Limited","issue":"16","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Oncol."],"published-print":{"date-parts":[[2014,12,31]]},"DOI":"10.2217\/fon.14.138","type":"journal-article","created":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T12:07:58Z","timestamp":1404216478000},"page":"2615-2627","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":59,"title":["How to manage asparaginase hypersensitivity in acute lymphoblastic leukemia"],"prefix":"10.1080","volume":"10","author":[{"given":"Michael J","family":"Burke","sequence":"first","affiliation":[{"name":"Division of Pediatric Oncology, Medical College of Wisconsin","place":["Milwaukee, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2014,7]]},"reference":[{"key":"e_1_3_2_3_1","unstructured":"American Cancer Society . Cancer Facts and Figures 2014 (2014). www.cancer.orgf"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60457-2"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24420"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/1911114a0"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25489"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.5.1211"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.7.1525"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.43.2070"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401007"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(03)00110-8"},{"key":"e_1_3_2_13_1","unstructured":"Keding RE . Discontinuation of Elspar (asparaginase for injection) 10.000 IU (2012). www.fda.gov"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3181e003c7"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-01-480822"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-008-0026-9"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1040-8428(98)00015-8"},{"issue":"1","key":"e_1_3_2_18_1","first-page":"299","article-title":"Immunogenicity of native or pegylated E. coli and Erwinia asparaginases assessed by ELISA and surface plasmon resonance (SPR-biacore) assays of IgG antibodies (Ab) in sera from patients with acute lymphoblastic leukemia (ALL)","volume":"29","author":"Avramis VI","year":"2009","unstructured":"Avramis VI , AvramisEV, HunterW, LongMC. Immunogenicity of native or pegylated E. coli and Erwinia asparaginases assessed by ELISA and surface plasmon resonance (SPR-biacore) assays of IgG antibodies (Ab) in sera from patients with acute lymphoblastic leukemia (ALL). Anticancer Res.29(1), 299\u2013302 (2009).","journal-title":"Anticancer Res."},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/1043454212471728"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24938"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3181e6f003"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2012.102"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200404000-00002"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190701292049"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2001.03009.x"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.9.1780"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.6.1986"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-07-367904"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.22225"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-4811-9_69"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-10-534347"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31822d4d4e"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.5.1709"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2011.596963"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0222"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920701)70:1<201::AID-CNCR2820700131>3.0.CO;2-M"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-06-027714"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.10096"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0306-5251.2001.01464.x"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2001.03148.x"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403011"},{"issue":"1","key":"e_1_3_2_42_1","first-page":"9","article-title":"Evaluation of intramuscular versus intravenous administration of L-asparaginase in childhood leukemia","volume":"1","author":"Nesbit M","year":"1979","unstructured":"Nesbit M , ChardR, EvansA, KaronM, HammondGD. Evaluation of intramuscular versus intravenous administration of L-asparaginase in childhood leukemia. Am. J. Pediatr. Hematol. Oncol.1(1), 9\u201313 (1979).","journal-title":"Am. J. Pediatr. Hematol. Oncol."},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200544040-00003"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2009.162"},{"issue":"2","key":"e_1_3_2_45_1","first-page":"99","article-title":"Antibody response to Escherichia coli L-asparaginase. Prognostic significance and clinical utility of antibody measurement","volume":"8","author":"Cheung NK","year":"1986","unstructured":"Cheung NK , ChauIY, CocciaPF. Antibody response to Escherichia coli L-asparaginase. Prognostic significance and clinical utility of antibody measurement. Am. J. Pediatr. Hematol. Oncol.8(2), 99\u2013104 (1986).","journal-title":"Am. J. Pediatr. Hematol. Oncol."},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401162"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-07-035006"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19991001)86:7<1203::AID-CNCR15>3.0.CO;2-3"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31828e5471"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23380"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-04-149443"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002800100286"},{"key":"e_1_3_2_53_1","volume-title":"The Meeting of the American Society of Pediatric Hematology Oncology","author":"Petersen W","year":"2010","unstructured":"Petersen W , ClarkD, SennS, CashT, KellerF, LewG. PEGaspargase administration in children with acute lymphoblastic leukemia. Presented at: The Meeting of the American Society of Pediatric Hematology Oncology. Montreal, CanadaApril7\u201310, 2010."},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820401)49:7<1378::AID-CNCR2820490713>3.0.CO;2-Z"},{"key":"e_1_3_2_55_1","volume-title":"Asparaginase In: Asparaginase in Treatment of Acute Leukemias: New Directions for Clinical Research","author":"Asselin BL","year":"2003","unstructured":"Asselin BL , KurtzbergJ. Asparaginase In: Asparaginase in Treatment of Acute Leukemias: New Directions for Clinical Research, PuiCH (Ed.). Humana Press, NJ, USA (2003)."},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2010.94"},{"key":"e_1_3_2_57_1","unstructured":"Hunger S COG Pharmacy Committee. Parental and oral chemotherapy administration guidelines used by the Children\u2018s Oncology Group (Version 6). Archives of the Children\u2018s Oncology Group (2010)."},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e32835d7d85"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401310"},{"issue":"11","key":"e_1_3_2_60_1","first-page":"4554","article-title":"L-asparaginase pharmacokinetics and asparagine levels in cerebrospinal fluid of rhesus monkeys and humans","volume":"41","author":"Riccardi R","year":"1981","unstructured":"Riccardi R , HolcenbergJS, GlaubigerDL, WoodJH, PoplackDG. L-asparaginase pharmacokinetics and asparagine levels in cerebrospinal fluid of rhesus monkeys and humans. Cancer Res.41(11 Pt 1), 4554\u20134558 (1981).","journal-title":"Cancer Res."},{"key":"e_1_3_2_61_1","volume-title":"Erwinaze \u00ae [Package Insert]","year":"2014","unstructured":"Erwinaze \u00ae [Package Insert]. Eusa Pharma (USA) Inc., PA, USA, March2014."},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-09-045351"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.11.411"},{"issue":"24","key":"e_1_3_2_64_1","first-page":"6568","article-title":"Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor.","volume":"51","author":"Asselin BL","year":"1991","unstructured":"Asselin BL , LorensonMY, WhitinJCet al. Measurement of serum L-asparagine in the presence of L-asparaginase requires the presence of an L-asparaginase inhibitor. Cancer Res. 51(24), 6568\u20136573 (1991).","journal-title":"Cancer Res."},{"key":"e_1_3_2_65_1","first-page":"556A","article-title":"Occurrence of an antibody to poly(ethylene glycol) in normal donors.","volume":"102","author":"Armstrong JK","year":"2003","unstructured":"Armstrong JK , LegerR, WenbyRBet al. Occurrence of an antibody to poly(ethylene glycol) in normal donors. Blood 102, 556A (2003).","journal-title":"Blood"},{"key":"e_1_3_2_66_1","unstructured":"Aibiotech Inc. L-asparaginase Assay for Leukemia Patients. December 2013."},{"key":"e_1_3_2_67_1","unstructured":"Aibiotech Inc. Laboratory Instructions Manual Assay of Clinical Samples fo L-Asparaginase Levels. December 2013."},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.2174\/157489212798358001"}],"container-title":["Future Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/fon.14.138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T09:39:28Z","timestamp":1761903568000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/fon.14.138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":66,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2014,12,31]]}},"alternative-id":["10.2217\/fon.14.138"],"URL":"https:\/\/doi.org\/10.2217\/fon.14.138","relation":{},"ISSN":["1479-6694","1744-8301"],"issn-type":[{"value":"1479-6694","type":"print"},{"value":"1744-8301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2014-07-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}