{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T06:11:00Z","timestamp":1764655860469},"reference-count":97,"publisher":"Informa UK Limited","issue":"2","license":[{"start":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T00:00:00Z","timestamp":1406505600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"National Cancer Institute grants","award":["U01CA84986 and K01CA164092"],"award-info":[{"award-number":["U01CA84986 and K01CA164092"]}]},{"name":"NCI\u2019s Clinical Proteomic Tumor Analysis Consortium initiative","award":["U24CA160036"],"award-info":[{"award-number":["U24CA160036"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Oncol."],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.2217\/fon.14.165","type":"journal-article","created":{"date-parts":[[2014,7,28]],"date-time":"2014-07-28T11:33:02Z","timestamp":1406547182000},"page":"233-249","update-policy":"http:\/\/dx.doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":23,"title":["Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile"],"prefix":"10.1080","volume":"11","author":[{"given":"Luciane Tsukamoto","family":"Kagohara","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana L","family":"Schussel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"},{"name":"Department of Oral Medicine, Post Graduation Program in Dentistry,Universidade Federal do Paran\u00e1,\rCuritiba,\rBrazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tejaswini","family":"Subbannayya","sequence":"additional","affiliation":[{"name":"Institute of Bioinformatics,\rWhitefield,\rBangalore 560066,\rKarnataka,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandini","family":"Sahasrabuddhe","sequence":"additional","affiliation":[{"name":"Institute of Bioinformatics,\rWhitefield,\rBangalore 560066,\rKarnataka,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia","family":"Lebron","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana","family":"Brait","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonel","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanca L.","family":"Valle","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Pirini","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Jahuira","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaime","family":"Lopez","sequence":"additional","affiliation":[{"name":"Universidad de La Frontera,Facultad de Medicina,Departamento de Anatom\u00eda Patol\u00f3gica,Laboratorio Patolog\u00eda Molecular,BIOREN-CEGIN,\rTemuco,\rChile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo","family":"Letelier","sequence":"additional","affiliation":[{"name":"Universidad de La Frontera,Facultad de Medicina,Departamento de Anatom\u00eda Patol\u00f3gica,Laboratorio Patolog\u00eda Molecular,BIOREN-CEGIN,\rTemuco,\rChile"},{"name":"Escuela Ciencias de la Salud,Universidad Cat\u00f3lica de Temuco,\rTemuco,\rChile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscilla","family":"Brebi-Mieville","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"},{"name":"Universidad de La Frontera,Facultad de Medicina,Departamento de Anatom\u00eda Patol\u00f3gica,Laboratorio Patolog\u00eda Molecular,BIOREN-CEGIN,\rTemuco,\rChile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Ili","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"},{"name":"Universidad de La Frontera,Facultad de Medicina,Departamento de Anatom\u00eda Patol\u00f3gica,Laboratorio Patolog\u00eda Molecular,BIOREN-CEGIN,\rTemuco,\rChile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akhilesh","family":"Pandey","sequence":"additional","affiliation":[{"name":"McKusick\u2013Nathans Institute of Genetic Medicine,\rBaltimore,\rMD 21205,\rUSA"},{"name":"Department of Biological Chemistry,\rBaltimore,\rMD 21205,\rUSA"},{"name":"Department of Oncology,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21205,\rUSA"},{"name":"Department of Pathology,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21205,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditi","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"},{"name":"Institute of Bioinformatics,\rWhitefield,\rBangalore 560066,\rKarnataka,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Sidransky","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Guerrero-Preston","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21231,\rUSA"},{"name":"Department of Oncology,Johns Hopkins University School of Medicine,\rBaltimore,\rMD 21205,\rUSA"},{"name":"University of Puerto Rico School of Medicine,Department of Obstetrics &amp; Gynecology,\rSan Juan,\rPuerto Rico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2014,7,28]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i47.6396"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-006-0028-1"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.51.6.349"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/GICTT.S16578"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2010.02.011"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.21683"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1868-7083-4-11"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21208"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(03)01021-0"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2008.03192.x"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20526"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.5009\/gnl.2012.6.2.172"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2003.02.014"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0579"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-005-1752-3"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mc.20457"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/93.14.1054"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-1511"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-09-0054"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/157829"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-4763"},{"issue":"9","key":"e_1_3_5_24_1","first-page":"2216","article-title":"Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR\u2013based microsatellite analysis","volume":"63","author":"Hoque MO","year":"2003","unstructured":"Hoque MO , LeeCC, CairnsP, SchoenbergM, SidranskyD. Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR\u2013based microsatellite analysis. Cancer Res.63(9), 2216\u20132222 (2003).","journal-title":"Cancer Res."},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.07.009"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.5.6.12378"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20709"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.24050"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/597164"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22060"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-0821"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-1111-3"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.01.3516"},{"issue":"3","key":"e_1_3_5_34_1","first-page":"939","article-title":"Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients","volume":"61","author":"Rosas SL","year":"2001","unstructured":"Rosas SL , KochW, Da Costa CarvalhoMGet al. Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res.61(3), 939\u2013942 (2001).","journal-title":"Cancer Res."},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0799"},{"issue":"9","key":"e_1_3_5_36_1","first-page":"2368","article-title":"Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis","volume":"60","author":"Esteller M","year":"2000","unstructured":"Esteller M , ToyotaM, Sanchez\u2013CespedesMet al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis. Cancer Res.60(9), 2368\u20132371 (2000).","journal-title":"Cancer Res."},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-3304"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-3923"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070878"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"issue":"5","key":"e_1_3_5_41_1","first-page":"1114","article-title":"A systematic profile of DNA methylation in human cancer cell lines","volume":"63","author":"Paz MF","year":"2003","unstructured":"Paz MF , FragaMF, AvilaSet al. A systematic profile of DNA methylation in human cancer cell lines. Cancer Res.63(5), 1114\u20131121 (2003).","journal-title":"Cancer Res."},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1279"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.01.029"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.7.687"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500398102"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3130"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-0324"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25248"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djj265"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/701814"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-3049"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.2.4.5214"},{"issue":"6","key":"e_1_3_5_53_1","first-page":"1653","article-title":"Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2\u2013M cell cycle arrest","volume":"26","author":"Sato K","year":"2005","unstructured":"Sato K , KitajimaY, KohyaN, MiyoshiA, KogaY, MiyazakiK. Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2\u2013M cell cycle arrest. Int. J. Oncol.26(6), 1653\u20131661 (2005).","journal-title":"Int. J. Oncol."},{"issue":"5","key":"e_1_3_5_54_1","first-page":"1773","article-title":"Promoter methylation of INK4a\/ARF as detected in bile\u2013significance for the differential diagnosis in biliary disease","volume":"9","author":"Klump B","year":"2003","unstructured":"Klump B , HsiehCJ, DetteSet al. Promoter methylation of INK4a\/ARF as detected in bile\u2013significance for the differential diagnosis in biliary disease. Clin. Cancer Res.9(5), 1773\u20131778 (2003).","journal-title":"Clin. Cancer Res."},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2006.00320.x"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.18.9821"},{"issue":"16","key":"e_1_3_5_57_1","first-page":"3899","article-title":"Quantitative analysis of aberrant p16 methylation using real\u2013time quantitative methylation\u2013specific polymerase chain reaction","volume":"59","author":"Lo YM","year":"1999","unstructured":"Lo YM , WongIH, ZhangJ, TeinMS, NgMH, HjelmNM. Quantitative analysis of aberrant p16 methylation using real\u2013time quantitative methylation\u2013specific polymerase chain reaction. Cancer Res.59(16), 3899\u20133903 (1999).","journal-title":"Cancer Res."},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-2888"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1204455"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1006\/geno.2002.6805"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25569"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.24.9891"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-011-0260-8"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2215"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgq038"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1299593"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040162"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3220"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7422"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kve185"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2050.2008.00862.x"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-419X(97)00008-5"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.1.139"},{"issue":"10","key":"e_1_3_5_74_1","first-page":"2405","article-title":"Silencing of p16\/CDKN2 expression in human gliomas by methylation and chromatin condensation","volume":"56","author":"Costello JF","year":"1996","unstructured":"Costello JF , BergerMS, HuangHS, CaveneeWK. Silencing of p16\/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res.56(10), 2405\u20132410 (1996).","journal-title":"Cancer Res."},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.22.12754"},{"issue":"8","key":"e_1_3_5_76_1","first-page":"3225","article-title":"A gene hypermethylation profile of human cancer","volume":"61","author":"Esteller M","year":"2001","unstructured":"Esteller M , CornPG, BaylinSB, HermanJG. A gene hypermethylation profile of human cancer. Cancer Res.61(8), 3225\u20133229 (2001).","journal-title":"Cancer Res."},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1080\/15216540701488358"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2004.tb03254.x"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-1137-3"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207316"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-05-2543"},{"issue":"6","key":"e_1_3_5_82_1","first-page":"4021","article-title":"The effect of o6\u2013methylguanine\u2013DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells","volume":"25","author":"Sato K","year":"2005","unstructured":"Sato K , KitajimaY, KogaY, MiyazakiK. The effect of o6\u2013methylguanine\u2013DNA methyltransferase (MGMT) and mismatch repair gene (hMLH1) status on the sensitivity to alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea(ACNU) in gallbladder carcinoma cells. Anticancer Res.25(6B), 4021\u20134028 (2005).","journal-title":"Anticancer Res."},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020576606004"},{"key":"e_1_3_5_84_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-1245"},{"key":"e_1_3_5_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(01)00449-9"},{"key":"e_1_3_5_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/301089a0"},{"key":"e_1_3_5_87_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2011-0902"},{"key":"e_1_3_5_88_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-4061"},{"key":"e_1_3_5_89_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.20830"},{"key":"e_1_3_5_90_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgt342"},{"key":"e_1_3_5_91_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-12-0859"},{"key":"e_1_3_5_92_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.125872.111"},{"key":"e_1_3_5_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2011.05.009"},{"key":"e_1_3_5_94_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2315"},{"key":"e_1_3_5_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2010.09.009"},{"issue":"1","key":"e_1_3_5_96_1","first-page":"24","article-title":"Global DNA methylation: a common early event in oral cancer cases with exposure to environmental carcinogens or viral agents","volume":"28","author":"Guerrero\u2013Preston R","year":"2009","unstructured":"Guerrero\u2013Preston R , BaezA, BlancoA, BerdascoM, FragaM, EstellerM. Global DNA methylation: a common early event in oral cancer cases with exposure to environmental carcinogens or viral agents. Puerto Rico Health Sci. J.28(1), 24\u201329 (2009).","journal-title":"Puerto Rico Health Sci. J."},{"key":"e_1_3_5_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2006.08.002"},{"key":"e_1_3_5_98_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23315"},{"key":"e_1_3_5_99_1","doi-asserted-by":"publisher","DOI":"10.3109\/1354750X.2012.717105"}],"container-title":["Future Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/fon.14.165","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T06:43:52Z","timestamp":1719125032000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/fon.14.165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,28]]},"references-count":97,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.2217\/fon.14.165"],"URL":"https:\/\/doi.org\/10.2217\/fon.14.165","relation":{},"ISSN":["1479-6694","1744-8301"],"issn-type":[{"value":"1479-6694","type":"print"},{"value":"1744-8301","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,28]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifon20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2014-07-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}