{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:00:51Z","timestamp":1740153651680,"version":"3.37.3"},"reference-count":55,"publisher":"Informa UK Limited","issue":"4","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["NIAID AI1077473"],"award-info":[{"award-number":["NIAID AI1077473"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HIV Ther."],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.2217\/hiv.09.20","type":"journal-article","created":{"date-parts":[[2009,7,6]],"date-time":"2009-07-06T15:13:23Z","timestamp":1246893203000},"page":"351-360","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Implications of New Findings in HIV Basic Research"],"prefix":"10.2217","volume":"3","author":[{"given":"Manish","family":"Sagar","sequence":"first","affiliation":[{"name":"Brigham and Women\u2018s Hospital, Harvard Medical School, 65 Landsdowne Street, Room447, Cambridge, MA02139, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,6]]},"reference":[{"key":"e_1_3_3_3_1_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6601823"},{"key":"e_1_3_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6189183"},{"key":"e_1_3_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07352"},{"key":"e_1_3_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1160355"},{"key":"e_1_3_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0703-853"},{"key":"e_1_3_3_3_6_1","first-page":"138","article-title":"Update of the drug resistance mutations in HIV-1.","volume":"16","author":"Johnson VA","year":"2008","unstructured":"Johnson VA , Brun-VezinetF, ClotetBet al.: Update of the drug resistance mutations in HIV-1.Top. HIV Med.16, 138\u2013145(2008).","journal-title":"Top. HIV Med."},{"key":"e_1_3_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2008.08.003"},{"key":"e_1_3_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-009-0006-z"},{"key":"e_1_3_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5283.1856"},{"key":"e_1_3_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80110-5"},{"key":"e_1_3_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/382722a0"},{"key":"e_1_3_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1369"},{"key":"e_1_3_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32831fb540"},{"key":"e_1_3_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143767"},{"key":"e_1_3_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1086\/596067"},{"key":"e_1_3_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003636"},{"key":"e_1_3_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1152725"},{"key":"e_1_3_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2008.10.004"},{"key":"e_1_3_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.07.032"},{"key":"e_1_3_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5265.1167"},{"key":"e_1_3_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-126-12-199706150-00003"},{"key":"e_1_3_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00444-08"},{"key":"e_1_3_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.5.555"},{"key":"e_1_3_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0807252"},{"key":"e_1_3_3_3_25_1","unstructured":"Sterne J : When to start consortium: when should HIV-1 infected persons initiate ART? Collaborative analysis of HIV cohort studies. Presented at: 16th Conference on Retroviruses and Opportunistic Infections. Montreal Canada 8\u201311 February 2009."},{"key":"e_1_3_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2478(98)00159-X"},{"key":"e_1_3_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199807000-00011"},{"key":"e_1_3_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1086\/695852"},{"key":"e_1_3_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1741"},{"key":"e_1_3_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1521"},{"key":"e_1_3_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1101160"},{"key":"e_1_3_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706135"},{"key":"e_1_3_3_3_33_1","unstructured":"Losso M Abrams DI; INSIGHT ESPRIT group: Effect of interleukin-2 on clinical outcomes in patients with a CD4+ cell count of 300\/mm3; primary results of the ESPIRIT study. Presented at: 16th Conference on Retroviruses and Opportunistic Infections. Montreal Canada 8\u201311 February 2009."},{"key":"e_1_3_3_3_34_1","unstructured":"Levy Y ; SILCAAT Scientific committee: Effect of interleukin-2 on clinical outcomes in patients with CD4+ cell count 50 to 299\/mm3: primary results of the SILCAAT study. Presented at: 16th Conference on Retroviruses and Opportunistic Infections. Montreal Canada 8\u201311 February 2009."},{"key":"e_1_3_3_3_35_1","first-page":"997","article-title":"Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment.","volume":"119","author":"Levy Y","year":"2009","unstructured":"Levy Y , LacabaratzC, WeissLet al.: Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment.J. Clin. Invest.119, 997\u20131007(2009).","journal-title":"J. Clin. Invest."},{"key":"e_1_3_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5255.1582"},{"key":"e_1_3_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5341.1295"},{"key":"e_1_3_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm880"},{"key":"e_1_3_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030122"},{"key":"e_1_3_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1165706"},{"key":"e_1_3_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.2174\/157016206776055084"},{"key":"e_1_3_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0802905"},{"key":"e_1_3_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1410"},{"key":"e_1_3_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.232688199"},{"key":"e_1_3_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705474104"},{"key":"e_1_3_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.3.1354-1360.1992"},{"key":"e_1_3_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-118-9-199305010-00004"},{"key":"e_1_3_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20051970"},{"key":"e_1_3_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1086\/524709"},{"key":"e_1_3_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.73.011303.073908"},{"key":"e_1_3_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1141453"},{"key":"e_1_3_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/418144a"},{"key":"e_1_3_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1932"},{"key":"e_1_3_3_4_2_1","unstructured":"Strategic Timing of Antiretroviral Treatment (START). http:\/\/clinicaltrials.gov\/ct2\/show\/NCT00867048?term=NCT00867048&rank=1"},{"key":"e_1_3_3_4_3_1","unstructured":"Safety and effectiveness of addition of maraviroc to ART regimens in HIV-infected adults with suboptimal CD4 T-cell count recovery despite sustained virologic suppression. http:\/\/clinicaltrials.gov\/ct2\/results?term=NCT00709111"}],"container-title":["HIV Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/hiv.09.20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T17:15:23Z","timestamp":1715966123000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/hiv.09.20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":55,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["10.2217\/hiv.09.20"],"URL":"https:\/\/doi.org\/10.2217\/hiv.09.20","relation":{},"ISSN":["1758-4310"],"issn-type":[{"type":"print","value":"1758-4310"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}