{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T04:11:36Z","timestamp":1782533496240,"version":"3.54.5"},"reference-count":89,"publisher":"Informa UK Limited","issue":"10","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.2217\/imt-2016-0052","type":"journal-article","created":{"date-parts":[[2016,9,8]],"date-time":"2016-09-08T09:38:38Z","timestamp":1473327518000},"page":"1219-1232","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":22,"title":["Restoring Anti-Oncodriver Th1 Responses with Dendritic Cell Vaccines in HER2\/\n            <i>neu<\/i>\n            -Positive Breast Cancer: Progress and Potential"],"prefix":"10.1080","volume":"8","author":[{"given":"Lucy M","family":"De La Cruz","sequence":"first","affiliation":[{"name":"Department of Endocrine &amp; Oncologic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia F","family":"Nocera","sequence":"additional","affiliation":[{"name":"Department of Endocrine &amp; Oncologic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J","family":"Czerniecki","sequence":"additional","affiliation":[{"name":"Department of Breast Oncology, H. Lee Moffitt Cancer Center, Tampa, FL33617, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,9,8]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1370"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4038"},{"issue":"1","key":"e_1_3_2_5_1","first-page":"16","article-title":"Existent T-cell and antibody immunity to HER-2\/neu protein in patients with breast cancer","volume":"54","author":"Disis ML","year":"1994","unstructured":"Disis ML , CalenoffE, MclaughlinGet al. Existent T-cell and antibody immunity to HER-2\/neu protein in patients with breast cancer. Cancer Res.54(1), 16\u201320 (1994).","journal-title":"Cancer Res."},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-08-1101"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-016-3692-4"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21973"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2015.1022301"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2015.5482"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(01)00064-8"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1203486"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2035"},{"issue":"6","key":"e_1_3_2_14_1","first-page":"675","article-title":"The variation and clinical significance of hormone receptors and HER-2 status from primary to metastatic lesions in breast cancer patients","volume":"37","author":"Zhu YY SW","year":"2015","unstructured":"Zhu YY SW , JiTF, GuoXQ, HuY, YangJl. The variation and clinical significance of hormone receptors and HER-2 status from primary to metastatic lesions in breast cancer patients. Tumour Biol.37(6), 675\u2013684 (2015).","journal-title":"Tumour Biol."},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-020711-074950"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.18.1.767"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.02.026"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199809)28:09<2760::AID-IMMU2760>3.0.CO;2-N"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/15182"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.10.5165"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2007.02719.x"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.5.2591"},{"issue":"22","key":"e_1_3_2_23_1","first-page":"6438","article-title":"Antigen-specific CD4+ T-cell help is required to activate a memory CD8+ T cell to a fully functional tumor killer cell","volume":"62","author":"Gao FG","year":"2002","unstructured":"Gao FG , KhammanivongV, LiuWJ, LeggattGR, FrazerIH, FernandoGJ. Antigen-specific CD4+ T-cell help is required to activate a memory CD8+ T cell to a fully functional tumor killer cell. Cancer Res.62(22), 6438\u20136441 (2002).","journal-title":"Cancer Res."},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3958"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8097337"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1385\/IR:29:1-3:187"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon.12.125"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26734"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e318235f512"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3119-y"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-015-0584-1"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.03.069"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.7370"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-014-0488-5"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.23.3494"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-7-58"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2010.03.001"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1586\/era.10.226"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.6789"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.57.6298"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2015.09.029"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S55279"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70336-9"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-28"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0b013e3283538293"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-0210"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-2062"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612023394089"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0073"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.728.11.2"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3511"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20052494"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.26.021607.090331"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2013.03.010"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-1254"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200690"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1305133"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e31821ca6ce"},{"issue":"5","key":"e_1_3_2_59_1","first-page":"375","article-title":"Immune targeting in breast cancer","volume":"29","author":"Ashley C-M","year":"2015","unstructured":"Ashley C-M , JeremyBF, LeishaAE. Immune targeting in breast cancer. Oncology29(5), 375 (2015).","journal-title":"Oncology"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00271"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.5041\/RMMJ.10158"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3239"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.4161\/onci.21335"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1510518113"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2010.87"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:CLIN.0000046133.35133.cc"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.09.016"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.158"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2015.1088519"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011331809881"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr2841"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0330705"},{"key":"e_1_3_2_73_1","first-page":"493","article-title":"Dendritic cell vaccine immunotherapy of cancer targeting MUC1 mucin","volume":"12","author":"Keiichi K","year":"2003","unstructured":"Keiichi K , TaguchiO, OzakiYet al. Dendritic cell vaccine immunotherapy of cancer targeting MUC1 mucin. Int. J. Mol. Med.12, 493\u2013502 (2003).","journal-title":"Int. J. Mol. Med."},{"issue":"1","key":"e_1_3_2_74_1","doi-asserted-by":"crossref","first-page":"e0145920","DOI":"10.1371\/journal.pone.0145920","article-title":"MUC1 vaccines, comprised of glycosylated or non-glycosylated peptides or tumor- derived MUC1, can circumvent immunoediting to control tumor growth in MUC1 transgenic mice","volume":"11","author":"Lakshmiarayanan V","year":"2016","unstructured":"Lakshmiarayanan V , SupekarNT, WeiJet al. MUC1 vaccines, comprised of glycosylated or non-glycosylated peptides or tumor- derived MUC1, can circumvent immunoediting to control tumor growth in MUC1 transgenic mice. PLoS One11(1), e0145920 (2016).","journal-title":"PLoS One"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-2765"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002067"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.3109\/09553002.2011.572112"},{"key":"e_1_3_2_78_1","first-page":"Doc02","article-title":"Telomerase-pulsed dendritic cells: preclinical results and outcome of a clinical Phase I\/II trial in patients with metastatic renal cell carcinoma","volume":"4","author":"M\u00e4rten A","year":"2006","unstructured":"M\u00e4rten A , SieversE, AlbersPet al. Telomerase-pulsed dendritic cells: preclinical results and outcome of a clinical Phase I\/II trial in patients with metastatic renal cell carcinoma. GMS German Med. Sci.4, Doc02 (2006).","journal-title":"GMS German Med. Sci."},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-0620-3"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1537685100"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/18.8.2149"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-014-2925-7"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2006.09.003"},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28566"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.20598"},{"key":"e_1_3_2_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2012.335"},{"key":"e_1_3_2_87_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.9696"},{"key":"e_1_3_2_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2012.12.001"},{"issue":"1","key":"e_1_3_2_89_1","first-page":"50","article-title":"TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients","volume":"6","author":"Kandioler-Eckersberger D","year":"2000","unstructured":"Kandioler-Eckersberger D , LudwigC, RudasMet al. TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clin. Cancer. Res.6(1), 50\u201356 (2000).","journal-title":"Clin. Cancer. Res."},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506230102"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0844-9"}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt-2016-0052","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T01:25:07Z","timestamp":1715995507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt-2016-0052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,8]]},"references-count":89,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.2217\/imt-2016-0052"],"URL":"https:\/\/doi.org\/10.2217\/imt-2016-0052","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,8]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}