{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:44:25Z","timestamp":1792277065204,"version":"4.4.0"},"reference-count":57,"publisher":"Informa UK Limited","issue":"7","funder":[{"name":"Merck"},{"name":"Stallergenes-Greer"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.2217\/imt-2017-0186","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T17:00:39Z","timestamp":1523379639000},"page":"605-616","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":7,"title":["Ragweed Sublingual Tablet Immunotherapy: Part I \u2013 Evidence-Based Clinical Efficacy and Safety"],"prefix":"10.1080","volume":"10","author":[{"given":"Peter Socrates","family":"Creticos","sequence":"first","affiliation":[{"name":"Division of Allergy &amp; Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD21224, USA"},{"name":"Creticos Research Group, Crownsville, MD21032, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Pfaar","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, Universit\u00e4tsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany"},{"name":"Center for Rhinology &amp; Allergology Wiesbaden, Wiesbaden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,4,10]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61509-8"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-4-3-130"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.01975.x"},{"key":"e_1_3_2_6_1","unstructured":"USDA (United States Department of Agriculture) Plant Database . Natural Resources Conservation Service website ( https:\/\/plants.usda.gov ) ( 11\/06\/2017 )."},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2015.09.016"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01780.x"},{"key":"e_1_3_2_9_1","unstructured":"Thermo Scientific website . www.phadia.com\/weed pollens\/allergens\/common ragweed ."},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.05.017"},{"key":"e_1_3_2_11_1","unstructured":"Bousquet J KhaltaevN CruzAAet al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization GA(2)LEN and AllerGen) . 63 ( S86 ) 8 \u2013 160 ( 2008 )."},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.09.034"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40629-014-0032-2"},{"key":"e_1_3_2_14_1","volume-title":"UpToDate","author":"Creticos PS","year":"2017","unstructured":"Creticos PS . Sublingual immunotherapy for allergic rhinoconjunctivitis and asthma . In : UpToDate . FeldwegAM ( Ed. ). UpToDate , Waltham, MA, USA ( 2017 ). ( Accessed 14February2018) \u00a9 2018 UpToDate . www.uptodate.com\/contents\/sublingual-immunotherapy-for-allergic-rhinoconjunctivitis-and-asthma ."},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13317"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.11.030"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.03.024"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.12.1088"},{"key":"e_1_3_2_19_1","first-page":"1","article-title":"Study of the role of antigen dosage in the treatment of pollinosis and pollen asthma","volume":"94","author":"Johnstone DE","year":"1957","unstructured":"Johnstone DE . Study of the role of antigen dosage in the treatment of pollinosis and pollen asthma . Am. J. Dis. Child.94 , 1 \u2013 5 ( 1957 ).","journal-title":"Am. J. Dis. Child."},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-8707(63)90069-8"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196509232731302"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-8707(68)90139-1"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-75-5-663"},{"key":"e_1_3_2_24_1","first-page":"273","article-title":"Maintenance immunotherapy in ragweed hay fever","volume":"47","author":"Norman PS","year":"1971","unstructured":"Norman PS , WinkenwerderWL , LichtensteinLM . Maintenance immunotherapy in ragweed hay fever . J. Allergy47 , 273 \u2013 282 ( 1971 ).","journal-title":"J. Allergy"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(78)90116-1"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(80)90158-X"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(80)90012-3"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199602223340804"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.02.035"},{"key":"e_1_3_2_30_1","first-page":"597","article-title":"Mediator release after nasal challenge with allergen","volume":"128","author":"Naclerio RM","year":"1983","unstructured":"Naclerio RM , MeierHL , Kagey-SobotkaAet al. Mediator release after nasal challenge with allergen . Am. Rev. Respir. Dis.128 , 597 \u2013 602 ( 1983 ).","journal-title":"Am. Rev. Respir. Dis."},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198406213102502"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI112233"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107204"},{"key":"e_1_3_2_34_1","first-page":"855","article-title":"Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six year prospective study","volume":"87","author":"Gleich GJ","year":"1991","unstructured":"Gleich GJ , ZimmermannEM , HendersonLL , YungingerJW . Effect of immunotherapy on immunoglobulin E and immunoglobulin G antibodies to ragweed antigens: a six year prospective study . J. Allergy Clin. Immunol.87 , 855 \u2013 866 ( 1991 ).","journal-title":"J. Allergy Clin. Immunol."},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(84)90490-1"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13138"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90325-4"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(91)90134-A"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.01.072"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.07.028"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.05.032"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.02.006"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2011.02.007"},{"issue":"12","key":"e_1_3_2_44_1","first-page":"CD002893","article-title":"Sublingual immunotherapy for allergic rhinitis","author":"Radulovic S","year":"2010","unstructured":"Radulovic S , CalderonMA , WilsonD , DurhamS . Sublingual immunotherapy for allergic rhinitis . Cochrane Database Syst. Rev. ( 12 ), CD002893 ( 2010 ).","journal-title":"Cochrane Database Syst. Rev."},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02583.x"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/1939-4551-7-6"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2016.12.009"},{"key":"e_1_3_2_48_1","unstructured":"FDA approval letter . www.fda.gov\/BiologicsBloodVaccines\/Allergenics\/UCM393572.htm.pdf ."},{"key":"e_1_3_2_49_1","unstructured":"Rabin RL . FDA CBER Clinical Review (3\/11\/2013) . www.fda.gov\/BiologicsBloodVaccines\/Allergenics ."},{"issue":"91","key":"e_1_3_2_50_1","first-page":"1","article-title":"Sublingual immunotherapy: World Allergy Organization position paper","volume":"64","author":"Canonica GW","year":"2009","unstructured":"Canonica GW , BousquetJ , CasaleTet al. Sublingual immunotherapy: World Allergy Organization position paper . Allergy64 ( S91 ), 1 \u2013 59 ( 2009 ).","journal-title":"Allergy"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2012.33.3605"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.03.019"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2013.03.013"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2014.04.018"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/1710-1492-10-55"},{"key":"e_1_3_2_56_1","first-page":"213","volume-title":"EAACI Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis","author":"Creticos PS","year":"2015","unstructured":"Creticos PS . New vaccines for allergen immunotherapy . In : EAACI Global Atlas of Allergic Rhinitis and Chronic Rhinosinusitis . AkdisCA , HellingsPW , AgacheI ( Eds ). European Academy of Allergyand Clinical Immunology , Zurich, Switzerland , Section E (8d) : 213 \u2013 216 ( 2015 )."},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2015.08.010"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-42499-6_26"},{"issue":"2","key":"e_1_3_2_59_1","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/alr.22073","article-title":"International consensus statement on allergy and rhinology: allergic rhinitis","volume":"8","author":"Wise SK","year":"2017","unstructured":"Wise SK , LinSY , ToskalaEet al. International consensus statement on allergy and rhinology: allergic rhinitis . Int. Forum Allergy Rhinol.8 ( 2 ), 108 \u2013 352 ; IX.D.2 ( 2017 ).","journal-title":"Int. Forum Allergy Rhinol."}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt-2017-0186","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T09:41:58Z","timestamp":1715938918000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt-2017-0186"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,10]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.2217\/imt-2017-0186"],"URL":"https:\/\/doi.org\/10.2217\/imt-2017-0186","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,10]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-12-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-10","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}