{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:18:35Z","timestamp":1791389915185,"version":"4.3.3"},"reference-count":92,"publisher":"Informa UK Limited","issue":"4","license":[{"start":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T00:00:00Z","timestamp":1547164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Pfizer China"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.2217\/imt-2018-0113","type":"journal-article","created":{"date-parts":[[2019,1,11]],"date-time":"2019-01-11T08:48:08Z","timestamp":1547196488000},"page":"321-333","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":41,"title":["Tuberculosis, Hepatitis B and Herpes Zoster in toFacitinib-Treated Patients with Rheumatoid Arthritis"],"prefix":"10.1080","volume":"11","author":[{"given":"Zhuoya","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Rheumatology & Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China, 210008"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Deng","sequence":"additional","affiliation":[{"name":"Pfizer Inc., Beijing, China, 100010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qizhe","family":"Wu","sequence":"additional","affiliation":[{"name":"Pfizer Inc., Beijing, China, 100010"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Rheumatology & Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China, 210008"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,1,11]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210715"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22783"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes283"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2016.02.028"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210708"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu185"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-210457"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12375"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/BTT.S148606"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S138677"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-017-0835-9"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2669"},{"key":"e_1_3_2_15_1","unstructured":"World Health Organization . Chronic diseases and health promotion: chronic rheumatic conditions . www.who.int\/chp\/topics\/rheumatic\/en ."},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2368"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2013.854059"},{"issue":"7","key":"e_1_3_2_18_1","first-page":"1436","article-title":"Increased risk of tuberculosis in patients with rheumatoid arthritis","volume":"30","author":"Carmona L","year":"2003","unstructured":"Carmona L , Hern\u00e1ndez-Garc\u00edaC , VadilloCet al. Increased risk of tuberculosis in patients with rheumatoid arthritis . J. Rheumatol.30 ( 7 ), 1436 \u2013 1439 ( 2003 ).","journal-title":"J. Rheumatol."},{"issue":"4","key":"e_1_3_2_19_1","first-page":"706","article-title":"Incidence of tuberculosis in Korean patients with rheumatoid arthritis (RA): effects of RA itself and of tumor necrosis factor blockers","volume":"34","author":"Seong SS","year":"2007","unstructured":"Seong SS , ChoiCB , WooJHet al. Incidence of tuberculosis in Korean patients with rheumatoid arthritis (RA): effects of RA itself and of tumor necrosis factor blockers . J. Rheumatol.34 ( 4 ), 706 \u2013 711 ( 2007 ).","journal-title":"J. Rheumatol."},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003551"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10524"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.16.9203"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.24.14447"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2012.08.019"},{"issue":"3","key":"e_1_3_2_25_1","first-page":"164","article-title":"Infections and biological therapy in patients with rheumatic diseases","volume":"18","author":"Atzeni F","year":"2016","unstructured":"Atzeni F , BatticciottoA , MasalaIF , TalottaR , BenucciM , Sarzi-PuttiniP . Infections and biological therapy in patients with rheumatic diseases . Isr. Med. Assoc. J.18 ( 3-4 ), 164 \u2013 167 ( 2016 ).","journal-title":"Isr. Med. Assoc. J."},{"key":"e_1_3_2_26_1","unstructured":"World Health Organization . Tuberculosis: global tuberculosis report 2017 . www.who.int\/tb\/publications ."},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8909834"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12106"},{"key":"e_1_3_2_29_1","unstructured":"World Health Organization . Latent tuberculosis infection . www.who.int\/tb\/publications ."},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60844-8"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-eular.1050"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.2147\/OARRR.S40526"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.2174\/187221307779815039"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.150057"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-012567"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209322"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbr.2017.05.003"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22768"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.13.0368"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.140102"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-203660"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20372"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1086\/421494"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204195"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu172"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38687"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar3455"},{"key":"e_1_3_2_48_1","unstructured":"World Health Organization . Hepatitis B: fact sheet . www.who.int\/mediacentre\/factsheets ."},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2015.06.002"},{"issue":"1","key":"e_1_3_2_50_1","first-page":"15","article-title":"Epidemiology of hepatitis B virus infection in China: current status and challenges","volume":"2","author":"Yan YP","year":"2014","unstructured":"Yan YP , SuHX , JiZH , ShaoZJ , PuZS . Epidemiology of hepatitis B virus infection in China: current status and challenges . J. Clin. Transl. Hepatol.2 ( 1 ), 15 \u2013 22 ( 2014 ).","journal-title":"J. Clin. Transl. Hepatol."},{"issue":"17","key":"e_1_3_2_51_1","first-page":"30234","article-title":"Risk-stratified management strategies for HBV reactivation in RA patients receiving biological and targeted therapy: a narrative review","author":"Chen YM","year":"2017","unstructured":"Chen YM , YangSS , ChenDY . Risk-stratified management strategies for HBV reactivation in RA patients receiving biological and targeted therapy: a narrative review . J. Microbiol. Immunol. Infect.pii:S1684\u2013S1182 ( 17 ), 30234 \u2013 30237 ( 2017 ).","journal-title":"J. Microbiol. Immunol. Infect."},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i36.10274"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2017.12.014"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2016.09.010"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2198-y"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23112"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-004833"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-014032"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.146"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.1099"},{"issue":"2","key":"e_1_3_2_61_1","first-page":"318","article-title":"The mechanism of action of tofacitinib - an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis","volume":"34","author":"Hodge JA","year":"2016","unstructured":"Hodge JA , KawabataTT , KrishnaswamiSet al. The mechanism of action of tofacitinib - an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis . Clin. Exp. Rheumatol.34 ( 2 ), 318 \u2013 328 ( 2016 ).","journal-title":"Clin. Exp. Rheumatol."},{"key":"e_1_3_2_62_1","unstructured":"US FDA . Xeljanz prescribing information . www.drugs.com ."},{"key":"e_1_3_2_63_1","unstructured":"EMA . Xeljanz 5 mg film-coated tablets. Summary of product characteristics . www.ema.europa.eu ."},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jis269"},{"issue":"6","key":"e_1_3_2_65_1","first-page":"1153","article-title":"Jaks, STATs, cytokines, and sepsis","volume":"9","author":"Scott MJ","year":"2002","unstructured":"Scott MJ , GodshallCJ , CheadleWG . Jaks, STATs, cytokines, and sepsis . Clin. Diagn. Lab. Immunol.9 ( 6 ), 1153 \u2013 1159 ( 2002 ).","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2006.11.025"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2008.00754.x"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1089\/1079990041689665"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3215"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207319"},{"issue":"1","key":"e_1_3_2_71_1","first-page":"32","article-title":"Efficacy and safety of tofacitinib in US and non-US rheumatoid arthritis patients: pooled analyses of Phase II and III","volume":"34","author":"Cohen SB","year":"2016","unstructured":"Cohen SB , KoenigA , WangLet al. Efficacy and safety of tofacitinib in US and non-US rheumatoid arthritis patients: pooled analyses of Phase II and III . Clin. Exp. Rheumatol.34 ( 1 ), 32 \u2013 36 ( 2016 ).","journal-title":"Clin. Exp. Rheumatol."},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1109071"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37816"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.13010"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/926836"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38745"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209131"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22470"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40189"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23769"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40187"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31618-5"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8417249"},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0880-2"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12754"},{"key":"e_1_3_2_86_1","first-page":"1","article-title":"2015 Revised recommendations for screening and management of tuberculosis infection in patients before and after anti-tumor necrosis factor-alpha biological treatment","volume":"29","author":"Chen Y","year":"2015","unstructured":"Chen Y , QiuY , HuangGet al. 2015 Revised recommendations for screening and management of tuberculosis infection in patients before and after anti-tumor necrosis factor-alpha biological treatment . Formosan J. Rheumatol.29 , 1 \u2013 9 ( 2015 ).","journal-title":"Formosan J. Rheumatol."},{"key":"e_1_3_2_87_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2015.1115815"},{"key":"e_1_3_2_88_1","first-page":"8","article-title":"2012 Screening and management of tuberculosis infection in patients scheduled for tumor necrosis factor-alpha inhibitors: consensus recommendations from the Taiwan Rheumatology Association","volume":"26","author":"Chen YH","year":"2012","unstructured":"Chen YH , SuW , ShenGet al. 2012 Screening and management of tuberculosis infection in patients scheduled for tumor necrosis factor-alpha inhibitors: consensus recommendations from the Taiwan Rheumatology Association . Formosan J. Rheumatol.26 , 8 \u2013 14 ( 2012 ).","journal-title":"Formosan J. Rheumatol."},{"key":"e_1_3_2_89_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-200489"},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-015-9675-4"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23190"},{"key":"e_1_3_2_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.03.021"},{"key":"e_1_3_2_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.meegid.2010.08.014"},{"key":"e_1_3_2_94_1","volume-title":"ACR\/ARHP Annual Meeting","author":"Bing N","year":"2015","unstructured":"Bing N , ZhouH , ZhangBet al. Genome-wide trans-ancestry meta-analysis of herpes zoster in RA and Pso patients treated with tofacitinib [Abstract no. 566] . ACR\/ARHP Annual Meeting . San Francisco, CA, USA , 11\u201316 November 2015 ."}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt-2018-0113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T14:09:48Z","timestamp":1715954988000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt-2018-0113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,11]]},"references-count":92,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.2217\/imt-2018-0113"],"URL":"https:\/\/doi.org\/10.2217\/imt-2018-0113","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,11]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}