{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T00:54:02Z","timestamp":1792803242762,"version":"4.5.0"},"reference-count":161,"publisher":"Informa UK Limited","issue":"2","funder":[{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","award":["C109738FE"],"award-info":[{"award-number":["C109738FE"]}],"id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Allegheny Health Network-Johns Hopkins University Cancer Research Fund","id":[{"id":"https:\/\/ror.org\/00za53h95","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institute of Health Prostate SPORE","award":["P50 CA058236"],"award-info":[{"award-number":["P50 CA058236"]}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-16-1-0410, W81XWH-17-1-0528"],"award-info":[{"award-number":["W81XWH-16-1-0410, W81XWH-17-1-0528"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Emerson Collective Cancer Research Fund","award":["643396"],"award-info":[{"award-number":["643396"]}],"id":[{"id":"https:\/\/ror.org\/04537p149","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.2217\/imt-2020-0066","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T04:22:31Z","timestamp":1604550151000},"page":"155-175","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":33,"title":["Overcoming Stromal Barriers to Immuno-Oncological Responses via Fibroblast Activation Protein-Targeted Therapy"],"prefix":"10.1080","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9807-7433","authenticated-orcid":false,"given":"W\u00a0Nathaniel","family":"Brennen","sequence":"first","affiliation":[{"name":"Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, MD\u00a021287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2437-1239","authenticated-orcid":false,"given":"Daniel L","family":"J Thorek","sequence":"additional","affiliation":[{"name":"Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO\u00a063310, USA"},{"name":"Department of Biomedical Engineering, Washington University School of Medicine, Saint Louis, MO\u00a063310, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2890-9510","authenticated-orcid":false,"given":"Wen","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD21287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7477-4012","authenticated-orcid":false,"given":"Timothy E","family":"Krueger","sequence":"additional","affiliation":[{"name":"Department of Pharmacology &amp; Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD\u00a021287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizamma","family":"Antony","sequence":"additional","affiliation":[{"name":"Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, MD\u00a021287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel R","family":"Denmeade","sequence":"additional","affiliation":[{"name":"Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, MD\u00a021287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3854-4658","authenticated-orcid":false,"given":"John T","family":"Isaacs","sequence":"additional","affiliation":[{"name":"Department of Oncology, Sidney Kimmel Comprehensive Cancer Center (SKCCC), Johns Hopkins University, Baltimore, MD\u00a021287, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,11,5]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-11-0340"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.imlet.2015.06.005"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23738"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2018.01.011"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0096-5"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07582-3"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-19-0094"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2019.02.032"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.5.12.3354"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3142"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20162024"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2017.12.003"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-18-0098"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.03.010"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-018-0275-3"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi701921b"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.17362"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-1228"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23145"},{"key":"e_1_3_4_22_1","first-page":"10.19.11","article-title":"Preparation of extracellular matrices produced by cultured and primary fibroblasts","volume":"33","author":"Beacham DA","year":"2007","unstructured":"Beacham DA , AmatangeloMD , CukiermanE. Preparation of extracellular matrices produced by cultured and primary fibroblasts. Curr. Protoc. Cell Biol.33, 10.19.11\u201310.19.21 (2007).","journal-title":"Curr. Protoc. Cell Biol."},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C500092200"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.12.5657"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202770200"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2016.05.001"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.51.36505"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2006.10.004"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2008.07241.x"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2011.06.008"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1530\/ERC-13-0151"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.9.3110"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-014-1292-0"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-08-3452"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20151085"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.710582"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2019.04.063"},{"issue":"6","key":"e_1_3_4_38_1","doi-asserted-by":"crossref","first-page":"e0178987","DOI":"10.1371\/journal.pone.0178987","article-title":"Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease","volume":"12","author":"Uitte De Willige S","year":"2017","unstructured":"Uitte De Willige S , KeaneFM , BowenDGet al. Circulating fibroblast activation protein activity and antigen levels correlate strongly when measured in liver disease and coronary heart disease. PLoS ONE12(6), e0178987 (2017).","journal-title":"PLoS ONE"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fob.2013.12.001"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm500031w"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-12900-8"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.9b00191"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.18.7235"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116683"},{"issue":"9","key":"e_1_3_4_45_1","first-page":"2912","article-title":"Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling","volume":"8","author":"Tuxhorn JA","year":"2002","unstructured":"Tuxhorn JA , AyalaGE , SmithMJ , SmithVC , DangTD , RowleyDR. Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin. Cancer Res.8(9), 2912\u20132923 (2002).","journal-title":"Clin. Cancer Res."},{"issue":"13","key":"e_1_3_4_46_1","first-page":"4792","article-title":"Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer","volume":"9","author":"Ayala G","year":"2003","unstructured":"Ayala G , TuxhornJA , WheelerTMet al. Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer. Clin. Cancer Res.9(13), 4792\u20134801 (2003).","journal-title":"Clin. Cancer Res."},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23867"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0150"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.06.016"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.21.8296"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(97)00032-X"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.2174\/156652412803833607"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajur.2018.11.006"},{"issue":"12","key":"e_1_3_4_54_1","first-page":"6406","article-title":"Differential expression of cell surface antigens and glial fibrillary acidic protein in human astrocytoma subsets","volume":"46","author":"Rettig WJ","year":"1986","unstructured":"Rettig WJ , ChesaPG , BeresfordHRet al. Differential expression of cell surface antigens and glial fibrillary acidic protein in human astrocytoma subsets. Cancer Res.46(12 Pt 1), 6406\u20136412 (1986).","journal-title":"Cancer Res."},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2006.11.006"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2014.04.005"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA118.001046"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151269"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2015.11.004"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2008.0027"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.2.631"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.16.2096"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-2973"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neo.2019.10.005"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0007-0"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2019.12.010"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2015.08.001"},{"key":"e_1_3_4_68_1","volume-title":"Presented at: 100th AACR Annual Meeting.","author":"Brennen WN","year":"2009","unstructured":"Brennen WN , DenmeadeSR. Fibroblast activation protein (FAP) as a mediator of TGF-beta activation (Abstract #1125). Presented at: 100th AACR Annual Meeting.Denver, CO, USA (April 18-22, 2009)."},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(82)90260-2"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.12.3324.3324"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.9.4689"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471143030.cb1009s33"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/20.7.1185"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408360490460933"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1177\/44.8.8756760"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.03.024"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng1116"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R400029200"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2015.05.005"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00229"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.20531"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.2.580"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0029(20010215)52:4<354::AID-JEMT1020>3.0.CO;2-G"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114932"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M212953200"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.35.24947"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23871"},{"key":"e_1_3_4_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)35712-0"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0603-669"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.1078\/0171-9335-00297"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100043"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.11347"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.21.12607"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2008.00410.x"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38988"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06654-8"},{"key":"e_1_3_4_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.10.029"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1195300"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1320318110"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.92232"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aay4860"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2008.39"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1208"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.03.049"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2007-0054"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1006\/prep.2001.1572"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-006-0713-x"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2014.0538"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(00)76461-7"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09168.x"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910580314"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198612253152606"},{"issue":"5","key":"e_1_3_4_113_1","first-page":"1639","article-title":"A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer","volume":"9","author":"Scott AM","year":"2003","unstructured":"Scott AM , WisemanG , WeltSet al. A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clin. Cancer Res.9(5), 1639\u20131647 (2003).","journal-title":"Clin. Cancer Res."},{"issue":"1","key":"e_1_3_4_114_1","first-page":"44","article-title":"Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer","volume":"26","author":"Hofheinz RD","year":"2003","unstructured":"Hofheinz RD , Al-BatranSE , HartmannFet al. Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer. Onkologie26(1), 44\u201348 (2003).","journal-title":"Onkologie"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.6.11.4874"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2009.04.007"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-9-263"},{"key":"e_1_3_4_118_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm950732f"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-0447"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.10.2988"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2229"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.110"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-11-187"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20130110"},{"key":"e_1_3_4_125_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0027"},{"key":"e_1_3_4_126_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3041"},{"key":"e_1_3_4_127_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-1788"},{"key":"e_1_3_4_128_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20122344"},{"key":"e_1_3_4_129_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1412910111"},{"key":"e_1_3_4_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.02.019"},{"key":"e_1_3_4_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2019.02.003"},{"key":"e_1_3_4_132_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.562"},{"key":"e_1_3_4_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajur.2018.11.004"},{"key":"e_1_3_4_134_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-08-1170"},{"key":"e_1_3_4_135_1","doi-asserted-by":"publisher","DOI":"10.3109\/1061186X.2010.511225"},{"key":"e_1_3_4_136_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs336"},{"key":"e_1_3_4_137_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.22847"},{"key":"e_1_3_4_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/pros.23162"},{"key":"e_1_3_4_139_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01755"},{"key":"e_1_3_4_140_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI94258"},{"key":"e_1_3_4_141_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000000593"},{"key":"e_1_3_4_142_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29831"},{"key":"e_1_3_4_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/mto.2016.7"},{"key":"e_1_3_4_144_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e31818353e9"},{"key":"e_1_3_4_145_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aav5989"},{"key":"e_1_3_4_146_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-0644"},{"key":"e_1_3_4_147_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.114.152959"},{"key":"e_1_3_4_148_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.116.177931"},{"key":"e_1_3_4_149_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kex456"},{"key":"e_1_3_4_150_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.118.210435"},{"key":"e_1_3_4_151_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.118.210443"},{"key":"e_1_3_4_152_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.119.227967"},{"key":"e_1_3_4_153_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.119.236786"},{"key":"e_1_3_4_154_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-020-04859-y"},{"key":"e_1_3_4_155_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.06.040"},{"key":"e_1_3_4_156_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.118.215913"},{"key":"e_1_3_4_157_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-020-04882-z"},{"key":"e_1_3_4_158_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41181-020-00102-z"},{"key":"e_1_3_4_159_1","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.119.233122"},{"key":"e_1_3_4_160_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010088"},{"key":"e_1_3_4_161_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa6204"},{"key":"e_1_3_4_162_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000265"},{"key":"e_1_3_4_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.07.029"}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt-2020-0066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T20:23:43Z","timestamp":1715977423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt-2020-0066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,5]]},"references-count":161,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.2217\/imt-2020-0066"],"URL":"https:\/\/doi.org\/10.2217\/imt-2020-0066","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,5]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-03-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}