{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:39:19Z","timestamp":1790127559348,"version":"4.0.1"},"reference-count":77,"publisher":"Informa UK Limited","issue":"15","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81772457"],"award-info":[{"award-number":["81772457"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81802257"],"award-info":[{"award-number":["81802257"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871859"],"award-info":[{"award-number":["81871859"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172750"],"award-info":[{"award-number":["82172750"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172811"],"award-info":[{"award-number":["82172811"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2018A030313846"],"award-info":[{"award-number":["2018A030313846"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515012593"],"award-info":[{"award-number":["2021A1515012593"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.2217\/imt-2022-0175","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T09:26:30Z","timestamp":1692177990000},"page":"1275-1291","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["<i>CACNA1C<\/i>\n            Mutation as a Prognosis Predictor of Immune Checkpoint Inhibitor in Skin Cutaneous Melanoma"],"prefix":"10.1080","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1598-7116","authenticated-orcid":false,"given":"Yushan","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6324-0410","authenticated-orcid":false,"given":"Anqi","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2815-5595","authenticated-orcid":false,"given":"Tianqi","family":"Gu","sequence":"additional","affiliation":[{"name":"The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7655-4976","authenticated-orcid":false,"given":"Shuang","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3097-8619","authenticated-orcid":false,"given":"Jiarong","family":"Yao","sequence":"additional","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8215-2045","authenticated-orcid":false,"given":"Peng","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7217-0111","authenticated-orcid":false,"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Oncology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,8,16]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.3327"},{"issue":"1","key":"e_1_3_5_4_1","first-page":"286","article-title":"CARD11 alteration as a candidate biomarker of skin cutaneous melanoma treated with immune checkpoint blockade","volume":"13","author":"Si Y","year":"2021","unstructured":"Si Y , LinA , DingW , MengH , LuoP , ZhangJ. CARD11 alteration as a candidate biomarker of skin cutaneous melanoma treated with immune checkpoint blockade. Am. J. Transl. Res.13(1), 286\u2013300 (2021).","journal-title":"Am. J. Transl. Res."},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-019-0368-6"},{"issue":"1","key":"e_1_3_5_6_1","first-page":"286","article-title":"CARD11 alteration as a candidate biomarker of skin cutaneous melanoma treated with immune checkpoint blockade","volume":"13","author":"Si Y","year":"2021","unstructured":"Si Y , LinA , DingW , MengH , LuoP , ZhangJ. CARD11 alteration as a candidate biomarker of skin cutaneous melanoma treated with immune checkpoint blockade. Am. J. Transl. Res.13(1), 286\u2013300 (2021).","journal-title":"Am. J. Transl. Res."},{"issue":"4","key":"e_1_3_5_7_1","first-page":"63","article-title":"Epidemiology of melanoma","volume":"9","author":"Saginala K","year":"2021","unstructured":"Saginala K , BarsoukA , AluruJS , RawlaP , BarsoukA. Epidemiology of melanoma. Med. Sci.9(4), 63 (2021).","journal-title":"Med. Sci."},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06386.x"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-1550"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.26329"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.43"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.629330"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1709684"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1910836"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104621"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1003466"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503093"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2016.11.007"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv383"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz116"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113205"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-3054"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-020-02668-8"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0000000000000298"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3168-x"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121823"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23126667"},{"issue":"7","key":"e_1_3_5_29_1","first-page":"e125766","article-title":"Meta-analysis of public microarray datasets reveals voltage-gated calcium gene signatures in clinical cancer patients","volume":"10","author":"Wang C","year":"2015","unstructured":"Wang C , LaiM , PhanNN , SunZ , LinY. Meta-analysis of public microarray datasets reveals voltage-gated calcium gene signatures in clinical cancer patients. PLOS ONE10(7), e125766 (2015).","journal-title":"PLOS ONE"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21134771"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2022.110358"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-021-02025-8"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2172"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2005.02720.x"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-2146"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-021-01122-5"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13048-021-00830-z"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0200-2"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genom-111221-103208"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv1507"},{"issue":"1","key":"e_1_3_5_41_1","first-page":"A68","article-title":"The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge","volume":"19","author":"Tomczak KK","year":"2015","unstructured":"Tomczak KK , Czerwi\u0144skaPP , WiznerowiczMM. The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge. Contemp. Oncol. (Pozna\u0144, Poland)19(1A), A68\u2013A77 (2015).","journal-title":"Contemp. Oncol. (Pozna\u0144, Poland)"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11523-020-00703-3"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3246"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1713444"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0312-8"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy495"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40880-019-0427-z"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.239244.118"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw313"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-0327-7_17"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbac129"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-016-1070-5"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00333"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbaa176"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506580102"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-14-7"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.49020"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1508163"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1910231"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0382-x"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-018-0191-1"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2012.02.022"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3902"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3541"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20080099"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1699"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-0742"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.145"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2018.29"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2018.9"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14215270"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13030564"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-23-184"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aah3560"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.09.028"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-011-1172-6"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-0562-4"},{"issue":"9","key":"e_1_3_5_78_1","first-page":"2322","article-title":"Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression","volume":"63","author":"Dirkx AE","year":"2003","unstructured":"Dirkx AE , OudeEM , KuijpersMJet.al Tumor angiogenesis modulates leukocyte-vessel wall interactions in vivo by reducing endothelial adhesion molecule expression. Cancer Res.63(9), 2322\u20132329 (2003).","journal-title":"Cancer Res."},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aak9670"}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt-2022-0175","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T11:05:32Z","timestamp":1715943932000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt-2022-0175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,16]]},"references-count":77,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.2217\/imt-2022-0175"],"URL":"https:\/\/doi.org\/10.2217\/imt-2022-0175","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-07-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}