{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:36:53Z","timestamp":1791308213015,"version":"4.3.1"},"reference-count":101,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Immunotherapy"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.2217\/imt.16.4","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T10:04:08Z","timestamp":1457949848000},"page":"449-460","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":76,"title":["Mesothelin as a Target for Chimeric Antigen Receptor-Modified T Cells as Anticancer Therapy"],"prefix":"10.1080","volume":"8","author":[{"given":"Mark","family":"O\u2019Hara","sequence":"first","affiliation":[{"name":"Division of Hematologic Oncology of the University of Pennsylvania, 3400 Ciciv Center Boulevard, Perelman Center of Advanced Medicine, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin","family":"Stashwick","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology of the University of Pennsylvania, 3400 Ciciv Center Boulevard, Perelman Center of Advanced Medicine, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R","family":"Haas","sequence":"additional","affiliation":[{"name":"Section of Interventional Pulmonology & Thoracic Oncology of The University of Pennsylvania, 3400 Ciciv Center Boulevard, Perelman Center of Advanced Medicine, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janos L","family":"Tanyi","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology of the University of Pennsylvania, 3400 Ciciv Center Boulevard, Perelman Center of Advanced Medicine, PA, USA"},{"name":"Hospital of the University of Pennsylvania, 3400 Civic Center Boulevard, Jordan Center, Philadelphia, PA19104, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,3,14]]},"reference":[{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1407222"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21254"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-1610"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014-0422"},{"issue":"1","key":"e_1_3_2_7_1","first-page":"181","article-title":"Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium","volume":"52","author":"Chang K","year":"1992","unstructured":"Chang K , PaiLH, BatraJK, PastanI, WillinghamMC. Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium. Cancer Res.52(1), 181\u2013186 (1992).","journal-title":"Cancer Res."},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.1.136"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)42180-6"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910500308"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2010.08.002"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M312372200"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.8.2902-2906.2000"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0337"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199203000-00006"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200311000-00003"},{"issue":"12","key":"e_1_3_2_17_1","first-page":"3862","article-title":"Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE)","volume":"7","author":"Argani P","year":"2001","unstructured":"Argani P , Iacobuzio-DonahueC, RyuBet al. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin. Cancer Res.7(12), 3862\u20133868 (2001).","journal-title":"Clin. Cancer Res."},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910510408"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200302000-00002"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2018-4"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.193458"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-1862"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3429"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0114900"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-0155"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1309\/F1B64CL7H8VJKEAF"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20031435"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088133"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0b013e318221bed8"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2012.02214.x"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-31-84"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep01870"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-31-14"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006250-199901000-00005"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pai.00000141545.36485.d6"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-5-50"},{"issue":"5","key":"e_1_3_2_37_1","first-page":"501","article-title":"Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes","volume":"1","author":"Fujita K","year":"1995","unstructured":"Fujita K , IkarashiH, TakakuwaKet al. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin. Cancer Res.1(5), 501\u2013507 (1995).","journal-title":"Clin. Cancer Res."},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020177"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.09.039"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.11.136"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MP.0000056981.16578.C3"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-2614"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0869"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-0062"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006941"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28875"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2275"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0804"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-2121"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.57.4244"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2013-LB-291"},{"issue":"3","key":"e_1_3_2_52_1","first-page":"194","article-title":"Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials","volume":"4","author":"Jaffee EM","year":"1998","unstructured":"Jaffee EM , SchutteM, GossettJet al. Development and characterization of a cytokine-secreting pancreatic adenocarcinoma vaccine from primary tumors for use in clinical trials. Cancer J. Sci. Am.4(3), 194\u2013203 (1998).","journal-title":"Cancer J. Sci. Am."},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.1.145"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0371"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181fd271c"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e31829fb7a2"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-13-0926"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0813101106"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2011.256"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2880"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0170"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.5.1653"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-07-1989"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm827"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-1183"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-0674"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mt.6300104"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-294520"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.169.3950.1042"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.5.1999"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403302"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0102-70"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.1.104"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2009.83"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-344275"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103849"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.2025"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2007.028"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2009.210"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2013.03.012"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-10-387969"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.05.9964"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.17"},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI35700"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2005.07.688"},{"key":"e_1_3_2_86_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2011.070"},{"key":"e_1_3_2_87_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2013.075"},{"key":"e_1_3_2_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.52"},{"issue":"15","key":"e_1_3_2_89_1","first-page":"3007","article-title":"Safety and antitumor activity of chimeric antigen receptor modified T cells in patients with chemotherapy refractory metastatic pancreatic cancer","volume":"33","author":"Beatty GL","year":"2015","unstructured":"Beatty GL , O\u2019HaraMH, NelsonAMet al. Safety and antitumor activity of chimeric antigen receptor modified T cells in patients with chemotherapy refractory metastatic pancreatic cancer. ASCO Meeting Abstracts33(15 Suppl.), 3007 (2015).","journal-title":"ASCO Meeting Abstracts"},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5259.263"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5270.1939"},{"key":"e_1_3_2_92_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0608138103"},{"key":"e_1_3_2_93_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-0494"},{"key":"e_1_3_2_94_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3002842"},{"key":"e_1_3_2_95_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215134"},{"key":"e_1_3_2_96_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-2627"},{"key":"e_1_3_2_97_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010162"},{"key":"e_1_3_2_98_1","doi-asserted-by":"publisher","DOI":"10.4161\/21624011.2014.970027"},{"key":"e_1_3_2_99_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-13-0006"},{"key":"e_1_3_2_100_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082742"},{"key":"e_1_3_2_101_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00254"},{"key":"e_1_3_2_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0710198105"},{"key":"e_1_3_2_103_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2015-CT105"}],"container-title":["Immunotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/imt.16.4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T00:22:04Z","timestamp":1715991724000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/imt.16.4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,14]]},"references-count":101,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.2217\/imt.16.4"],"URL":"https:\/\/doi.org\/10.2217\/imt.16.4","relation":{},"ISSN":["1750-743X","1750-7448"],"issn-type":[{"value":"1750-743X","type":"print"},{"value":"1750-7448","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iimy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-03-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}