{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:04:09Z","timestamp":1764997449042,"version":"3.40.5"},"reference-count":38,"publisher":"Informa UK Limited","issue":"11","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine (Lond.)"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.2217\/nnm-2021-0446","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T09:32:52Z","timestamp":1652693572000},"page":"753-764","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":7,"title":["Antiproliferative and Apoptotic Potential of Methotrexate Lipid Nanoparticles in A Murine Breast Cancer Model"],"prefix":"10.1080","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3646-1808","authenticated-orcid":false,"given":"Chaitali","family":"Surve","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, Vivekanand Education Society\u2019s College of Pharmacy, Mumbai, India"},{"name":"Faculty of Pharmacy, Pacific Academy of Higher Education &amp; Research University, Udaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9248-5778","authenticated-orcid":false,"given":"Ananya","family":"Banerjee","sequence":"additional","affiliation":[{"name":"School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2788-2272","authenticated-orcid":false,"given":"Anupriya","family":"S","sequence":"additional","affiliation":[{"name":"School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8704-9648","authenticated-orcid":false,"given":"Rajasree","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6085-5911","authenticated-orcid":false,"given":"Dhiraj","family":"Kumar","sequence":"additional","affiliation":[{"name":"National Centre for Cell Science (NCCS), NCCS Complex, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6011-7791","authenticated-orcid":false,"given":"Ramesh","family":"Butti","sequence":"additional","affiliation":[{"name":"National Centre for Cell Science (NCCS), NCCS Complex, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3133-425X","authenticated-orcid":false,"given":"Mahadeo","family":"Gorain","sequence":"additional","affiliation":[{"name":"National Centre for Cell Science (NCCS), NCCS Complex, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7683-5504","authenticated-orcid":false,"given":"Sabyasachi","family":"Parida","sequence":"additional","affiliation":[{"name":"Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha24, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3534-4033","authenticated-orcid":false,"given":"Gopal C","family":"Kundu","sequence":"additional","affiliation":[{"name":"School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India"},{"name":"National Centre for Cell Science (NCCS), NCCS Complex, Pune, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya","family":"Shidhaye","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Vivekanand Education Society\u2019s College of Pharmacy, Mumbai, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinivas","family":"Patnaik","sequence":"additional","affiliation":[{"name":"School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,5,16]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2018.06.024"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2015.03.018"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S87271"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.06.001"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S146315"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers6031769"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.15171\/apb.2017.041"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13402-016-0281-9"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.6b00437"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S596"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0160042"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0373-9"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20133312"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-017-0004-3"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano9030474"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.15171\/apb.2015.043"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA03491F"},{"issue":"5","key":"e_1_3_5_19_1","first-page":"132","article-title":"Formulation and QBD based optimization of methotrexate-loaded solid lipid nanoparticles for an effective anti-cancer treatment","volume":"13","author":"Surve C","year":"2021","unstructured":"Surve C , SinghR, BanerjeeA, PatnaikS, ShidhayeS. Formulation and QBD based optimization of methotrexate-loaded solid lipid nanoparticles for an effective anti-cancer treatment. IJAP13(5), 132\u2013143 (2021).","journal-title":"IJAP"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2006.03.052"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/mp400269z"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-0661"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-2126"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2011.05.075"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.12.017"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/nano8020110"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.07.013"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2015.09.084"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/mp700086j"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2014.07.024"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297914080070"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2015.06.027"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.11.53"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S120969"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.12.201"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep28983"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2016.05.051"},{"key":"e_1_3_5_38_1","article-title":"Formulation, characterization and in vitro evaluation of methotrexate solid lipid nanoparticles","author":"Mulla J","year":"2009","unstructured":"Mulla J , SureshS, KhaziI. Formulation, characterization and in vitro evaluation of methotrexate solid lipid nanoparticles. RJPT (2009). https:\/\/rjptonline.org\/AbstractView.aspx?PID=2009-2-4-74","journal-title":"RJPT"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1166\/jnn.2006.457"}],"container-title":["Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/nnm-2021-0446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T19:50:11Z","timestamp":1716493811000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/nnm-2021-0446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":38,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.2217\/nnm-2021-0446"],"URL":"https:\/\/doi.org\/10.2217\/nnm-2021-0446","relation":{},"ISSN":["1743-5889","1748-6963"],"issn-type":[{"type":"print","value":"1743-5889"},{"type":"electronic","value":"1748-6963"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-11-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}