{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:22:50Z","timestamp":1767374570090,"version":"3.40.5"},"reference-count":92,"publisher":"Informa UK Limited","issue":"24","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine (Lond.)"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.2217\/nnm-2022-0234","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T10:49:28Z","timestamp":1674643768000},"page":"1871-1889","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["Intraductal Delivery of Nanocarriers for Ductal Carcinoma\n            <i>In Situ<\/i>\n            Treatment: A Strategy to Enhance Localized Delivery"],"prefix":"10.1080","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8249-9743","authenticated-orcid":false,"given":"Manisha","family":"Pandey","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Technology, School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"},{"name":"Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, 123031, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pung Xiau","family":"Wen","sequence":"additional","affiliation":[{"name":"School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giam Mun","family":"Ning","sequence":"additional","affiliation":[{"name":"School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gan Jia","family":"Xing","sequence":"additional","affiliation":[{"name":"School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liu Man","family":"Wei","sequence":"additional","affiliation":[{"name":"School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dinesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, 123031, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayashree","family":"Mayuren","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Technology, School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayuren","family":"Candasamy","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, School of Pharmacy, International Medical University, Kuala Lumpur, 57000, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bapi","family":"Gorain","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences &amp; Technology, Birla Institute of Technology, Mesra, Ranchi, 835215, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7941-0229","authenticated-orcid":false,"given":"Gaurav","family":"Gupta","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur, 302017, India"},{"name":"Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical &amp; Technical Sciences, Saveetha University, Chennai, 602105, India"},{"name":"Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, 248007, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7507-1159","authenticated-orcid":false,"given":"Kamal","family":"Dua","sequence":"additional","affiliation":[{"name":"Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, NSW 2007, Australia"},{"name":"Faculty of Health, Australian Research Centre in Complementary &amp; Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,1,25]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_3_3_3_1","DOI":"10.29289\/25945394202020200024"},{"doi-asserted-by":"publisher","key":"e_1_3_3_4_1","DOI":"10.1001\/jamanetworkopen.2020.17124"},{"unstructured":"World Health Organization. Breast cancer (2021). www.who.int\/news-room\/fact-sheets\/detail\/breast-cancer","key":"e_1_3_3_5_1"},{"unstructured":"American Cancer Society. Ductal carcinoma in situ (DCIS) (2021). www.cancer.org\/cancer\/breast-cancer\/about\/types-of-breast-cancer\/dcis.html","key":"e_1_3_3_6_1"},{"doi-asserted-by":"publisher","key":"e_1_3_3_7_1","DOI":"10.3390\/cancers13174287"},{"doi-asserted-by":"publisher","key":"e_1_3_3_8_1","DOI":"10.1210\/endocr\/bqab195"},{"doi-asserted-by":"publisher","key":"e_1_3_3_9_1","DOI":"10.1097\/PPO.0000000000000500"},{"unstructured":"International Agency for Research on Cancer World Health Organization. Global Cancer Observatory 2018 (2020). https:\/\/www.breastcancer.org\/facts-statistics","key":"e_1_3_3_10_1"},{"unstructured":"Canadian Cancer Statistics Advisory Committee Canadian Cancer Society. Canadian Cancer Statistics 2021. Statistics Canada and the Public Health Agency of Canada. (2021). https:\/\/cancer.ca\/en\/research\/cancer-statistics","key":"e_1_3_3_11_1"},{"unstructured":"Breastcancer.orgU.S. Breast Cancer Statistics. Breastcancer.org (2021). www.breastcancer.org\/symptoms\/understand_bc\/statistics","key":"e_1_3_3_12_1"},{"doi-asserted-by":"publisher","key":"e_1_3_3_13_1","DOI":"10.2217\/fon-2018-0555"},{"doi-asserted-by":"publisher","key":"e_1_3_3_14_1","DOI":"10.2217\/bmt.14.9"},{"doi-asserted-by":"publisher","key":"e_1_3_3_15_1","DOI":"10.1016\/j.ajpath.2019.03.002"},{"doi-asserted-by":"publisher","key":"e_1_3_3_16_1","DOI":"10.2217\/fon.11.72"},{"doi-asserted-by":"publisher","key":"e_1_3_3_17_1","DOI":"10.1186\/bcr2157"},{"unstructured":"Tomlinson-Hansen S Khan M Cassaro S. Breast ductal carcinoma in situ. StatPearls Publishing FL USA (2022).","key":"e_1_3_3_18_1"},{"doi-asserted-by":"publisher","key":"e_1_3_3_19_1","DOI":"10.1038\/s41416-019-0478-6"},{"doi-asserted-by":"publisher","key":"e_1_3_3_20_1","DOI":"10.1159\/000329005"},{"doi-asserted-by":"publisher","key":"e_1_3_3_21_1","DOI":"10.2217\/fon-2015-0071"},{"doi-asserted-by":"publisher","key":"e_1_3_3_22_1","DOI":"10.2217\/cer.13.3"},{"doi-asserted-by":"publisher","key":"e_1_3_3_23_1","DOI":"10.2217\/fon.09.25"},{"doi-asserted-by":"publisher","key":"e_1_3_3_24_1","DOI":"10.1159\/000485737"},{"doi-asserted-by":"publisher","key":"e_1_3_3_25_1","DOI":"10.1016\/j.ejcsup.2013.07.028"},{"doi-asserted-by":"publisher","key":"e_1_3_3_26_1","DOI":"10.1111\/tbj.13425"},{"doi-asserted-by":"publisher","key":"e_1_3_3_27_1","DOI":"10.1007\/s10549-021-06129-3"},{"doi-asserted-by":"publisher","key":"e_1_3_3_28_1","DOI":"10.1200\/JCO.21.00831"},{"doi-asserted-by":"publisher","key":"e_1_3_3_29_1","DOI":"10.1200\/JCO.2015.60.8588"},{"doi-asserted-by":"publisher","key":"e_1_3_3_30_1","DOI":"10.2217\/nnm-2021-0281"},{"doi-asserted-by":"publisher","key":"e_1_3_3_31_1","DOI":"10.2217\/epi-2021-0405"},{"doi-asserted-by":"publisher","key":"e_1_3_3_32_1","DOI":"10.1016\/j.ejps.2021.105890"},{"doi-asserted-by":"publisher","key":"e_1_3_3_33_1","DOI":"10.1016\/B978-0-12-821789-4.00006-0"},{"doi-asserted-by":"publisher","key":"e_1_3_3_34_1","DOI":"10.3390\/biomedicines9020114"},{"doi-asserted-by":"publisher","key":"e_1_3_3_35_1","DOI":"10.2217\/nnm-2017-0210"},{"doi-asserted-by":"publisher","key":"e_1_3_3_36_1","DOI":"10.2217\/nnm-2021-0123"},{"doi-asserted-by":"publisher","key":"e_1_3_3_37_1","DOI":"10.3892\/mco.2014.297"},{"doi-asserted-by":"publisher","key":"e_1_3_3_38_1","DOI":"10.1148\/radiol.2019181844"},{"doi-asserted-by":"publisher","key":"e_1_3_3_39_1","DOI":"10.2217\/bmt-2016-0026"},{"doi-asserted-by":"publisher","key":"e_1_3_3_40_1","DOI":"10.32604\/cmc.2021.013774"},{"doi-asserted-by":"publisher","key":"e_1_3_3_41_1","DOI":"10.1016\/j.ejso.2021.10.030"},{"doi-asserted-by":"publisher","key":"e_1_3_3_42_1","DOI":"10.1038\/s41416-019-0478-6"},{"doi-asserted-by":"publisher","key":"e_1_3_3_43_1","DOI":"10.1016\/j.gendis.2018.05.001"},{"issue":"3","key":"e_1_3_3_44_1","first-page":"179","article-title":"Is anti-hormonal treatment in DCIS of the breast a need?","volume":"8","author":"Tjalma W","year":"2016","unstructured":"Tjalma W. Is anti-hormonal treatment in DCIS of the breast a need? Facts Views Vis. Obstetr. Gynaecol. 8(3), 179\u2013181 (2016).","journal-title":"Facts Views Vis. Obstetr. Gynaecol."},{"doi-asserted-by":"publisher","key":"e_1_3_3_45_1","DOI":"10.1001\/jamanetworkopen.2021.1785"},{"doi-asserted-by":"publisher","key":"e_1_3_3_46_1","DOI":"10.1111\/tbj.12418"},{"issue":"2","key":"e_1_3_3_47_1","first-page":"17","article-title":"Breast cancer: conventional diagnosis and treatment modalities and recent patents and technologies","volume":"9","author":"Nounou MI","year":"2015","unstructured":"Nounou MI, ElAmrawy F, Ahmed N et al. Breast cancer: conventional diagnosis and treatment modalities and recent patents and technologies. Breast Cancer (Auckl) 9(Suppl. 2) 17\u201334 (2015).","journal-title":"Breast Cancer (Auckl)"},{"doi-asserted-by":"publisher","key":"e_1_3_3_48_1","DOI":"10.1016\/j.jconrel.2020.04.016"},{"key":"e_1_3_3_49_1","first-page":"2013","article-title":"Nanocarriers for diagnosis and targeting of breast cancer","author":"Sharma A","year":"2013","unstructured":"Sharma A, Jain N, Sareen R. Nanocarriers for diagnosis and targeting of breast cancer. Biomed. Res. Int. 2013 (2013).","journal-title":"Biomed. Res. Int."},{"doi-asserted-by":"publisher","key":"e_1_3_3_50_1","DOI":"10.2217\/bmt.12.69"},{"doi-asserted-by":"publisher","key":"e_1_3_3_51_1","DOI":"10.1053\/j.seminoncol.2015.09.003"},{"doi-asserted-by":"publisher","key":"e_1_3_3_52_1","DOI":"10.1016\/j.clbc.2013.02.002"},{"doi-asserted-by":"publisher","key":"e_1_3_3_53_1","DOI":"10.3390\/pharmaceutics13070960"},{"doi-asserted-by":"publisher","key":"e_1_3_3_54_1","DOI":"10.2147\/IJN.S140325"},{"doi-asserted-by":"publisher","key":"e_1_3_3_55_1","DOI":"10.1186\/bcr1410"},{"doi-asserted-by":"publisher","key":"e_1_3_3_56_1","DOI":"10.1126\/scitranslmed.3002368"},{"issue":"80","key":"e_1_3_3_57_1","first-page":"50692","article-title":"Intraductal injection for localized drug delivery to the mouse mammary gland","author":"Krause S","year":"2013","unstructured":"Krause S, Brock A, Ingber DE. Intraductal injection for localized drug delivery to the mouse mammary gland. J. Vis. Exp. (80), 50692 (2013).","journal-title":"J. Vis. Exp."},{"issue":"5","key":"e_1_3_3_58_1","first-page":"579","article-title":"The safety parameters of the study on intraductal cytotoxic agent delivery to the breast before mastectomy","volume":"26","author":"Zhang B","year":"2014","unstructured":"Zhang B, Love SM, Chen G et al. The safety parameters of the study on intraductal cytotoxic agent delivery to the breast before mastectomy. Chin. J. Cancer 26(5), 579 (2014).","journal-title":"Chin. J. Cancer"},{"doi-asserted-by":"publisher","key":"e_1_3_3_59_1","DOI":"10.2217\/nnm.14.154"},{"doi-asserted-by":"publisher","key":"e_1_3_3_60_1","DOI":"10.2147\/IJN.S146315"},{"doi-asserted-by":"publisher","key":"e_1_3_3_61_1","DOI":"10.2217\/nnm-2019-0308"},{"doi-asserted-by":"publisher","key":"e_1_3_3_62_1","DOI":"10.1016\/j.amjsurg.2011.06.027"},{"doi-asserted-by":"publisher","key":"e_1_3_3_63_1","DOI":"10.3389\/fmolb.2020.00193"},{"doi-asserted-by":"publisher","key":"e_1_3_3_64_1","DOI":"10.3390\/pharmaceutics10030134"},{"doi-asserted-by":"publisher","key":"e_1_3_3_65_1","DOI":"10.1155\/2020\/9184284"},{"doi-asserted-by":"publisher","key":"e_1_3_3_66_1","DOI":"10.3390\/cancers11050640"},{"doi-asserted-by":"publisher","key":"e_1_3_3_67_1","DOI":"10.1039\/C9TB02711D"},{"doi-asserted-by":"publisher","key":"e_1_3_3_68_1","DOI":"10.3389\/fchem.2020.597806"},{"doi-asserted-by":"publisher","key":"e_1_3_3_69_1","DOI":"10.1021\/acsabm.0c01272"},{"doi-asserted-by":"publisher","key":"e_1_3_3_70_1","DOI":"10.1186\/s12951-022-01605-4"},{"doi-asserted-by":"publisher","key":"e_1_3_3_71_1","DOI":"10.1158\/0008-5472.CAN-12-1683"},{"doi-asserted-by":"publisher","key":"e_1_3_3_72_1","DOI":"10.1186\/s12951-018-0392-8"},{"doi-asserted-by":"publisher","key":"e_1_3_3_73_1","DOI":"10.1002\/jin2.51"},{"doi-asserted-by":"publisher","key":"e_1_3_3_74_1","DOI":"10.1080\/10717544.2018.1440665"},{"doi-asserted-by":"publisher","key":"e_1_3_3_75_1","DOI":"10.2217\/nnm-2021-0130"},{"unstructured":"Husain S Yu M Khalid A. Optimizing a novel intraductal delivery of calcineurin inhibitors as a radiocontrast infusion formulation to prevent post-ERCP pancreatitis. STANFORD UNIV CA (2021). https:\/\/apps.dtic.mil\/sti\/citations\/AD1118329","key":"e_1_3_3_76_1"},{"doi-asserted-by":"publisher","key":"e_1_3_3_77_1","DOI":"10.1002\/lio2.306"},{"doi-asserted-by":"publisher","key":"e_1_3_3_78_1","DOI":"10.3390\/ph15091110"},{"key":"e_1_3_3_79_1","first-page":"21","article-title":"The role of drug delivery systems in cancer chemotherapy","volume":"9","author":"Juliano RL","year":"1976","unstructured":"Juliano RL. The role of drug delivery systems in cancer chemotherapy. Prog. Clin. Biol. Res. 9, 21\u201332 (1976).","journal-title":"Prog. Clin. Biol. Res."},{"issue":"2","key":"e_1_3_3_80_1","first-page":"441","article-title":"Intraductal drug delivery to the breast: effect of particle size and formulation on breast duct and lymph node retention","volume":"17","author":"Joseph MK","year":"2020","unstructured":"Joseph MK, Islam M, Reineke J et al. Intraductal drug delivery to the breast: effect of particle size and formulation on breast duct and lymph node retention. Mol. Pharm. 17(2), 441\u2013452 (2020).","journal-title":"Mol. Pharm."},{"doi-asserted-by":"publisher","key":"e_1_3_3_81_1","DOI":"10.1158\/1940-6207.CAPR-12-0228"},{"doi-asserted-by":"publisher","key":"e_1_3_3_82_1","DOI":"10.1007\/s10549-004-6455-6"},{"doi-asserted-by":"publisher","key":"e_1_3_3_83_1","DOI":"10.1158\/0008-5472.CAN-05-4329"},{"doi-asserted-by":"publisher","key":"e_1_3_3_84_1","DOI":"10.1093\/carcin\/bgs248"},{"doi-asserted-by":"publisher","key":"e_1_3_3_85_1","DOI":"10.3390\/ijms22010385"},{"doi-asserted-by":"publisher","key":"e_1_3_3_86_1","DOI":"10.1016\/j.toxrep.2019.04.003"},{"issue":"1","key":"e_1_3_3_87_1","first-page":"62","article-title":"Surgery versus monitoring and endocrine therapy for low-risk DCIS: the COMET Trial","volume":"102","author":"Youngwirth LM","year":"2017","unstructured":"Youngwirth LM, Boughey JC, Hwang ES. Surgery versus monitoring and endocrine therapy for low-risk DCIS: the COMET Trial. Bull. Am. Coll. Surg. 102(1), 62\u201363 (2017).","journal-title":"Bull. Am. Coll. Surg."},{"doi-asserted-by":"publisher","key":"e_1_3_3_88_1","DOI":"10.1016\/j.ejca.2015.05.008"},{"doi-asserted-by":"publisher","key":"e_1_3_3_89_1","DOI":"10.1016\/j.breast.2022.01.001"},{"doi-asserted-by":"publisher","key":"e_1_3_3_90_1","DOI":"10.1200\/JCO.19.00510"},{"issue":"2","key":"e_1_3_3_91_1","first-page":"441","article-title":"Intraductal drug delivery to the breast: effect of particle size and formulation on breast duct and lymph node retention","volume":"17","author":"Joseph MK","year":"2020","unstructured":"Joseph MK, Islam M, Reineke J et al. Intraductal drug delivery to the breast: effect of particle size and formulation on breast duct and lymph node retention. Mol. Pharm. 17(2), 441\u2013452 (2020).","journal-title":"Mol. Pharm."},{"issue":"36","key":"e_1_3_3_92_1","first-page":"7153","article-title":"An overview of nanotoxicity and nanomedicine research: principles, progress and implications for cancer therapy","volume":"3","author":"Wang Y","year":"2015","unstructured":"Wang Y, Santos A, Evdokiou A, Losic D. An overview of nanotoxicity and nanomedicine research: principles, progress and implications for cancer therapy. J. Mater. Chem. B3(36), 7153\u20137172 (2015).","journal-title":"J. Mater. Chem."},{"doi-asserted-by":"publisher","key":"e_1_3_3_93_1","DOI":"10.1016\/j.jare.2018.06.005"},{"doi-asserted-by":"publisher","key":"e_1_3_3_94_1","DOI":"10.1016\/j.addr.2018.06.024"}],"container-title":["Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.2217\/nnm-2022-0234","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T19:49:37Z","timestamp":1716493777000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.2217\/nnm-2022-0234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":92,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.2217\/nnm-2022-0234"],"URL":"https:\/\/doi.org\/10.2217\/nnm-2022-0234","relation":{},"ISSN":["1743-5889","1748-6963"],"issn-type":[{"type":"print","value":"1743-5889"},{"type":"electronic","value":"1748-6963"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}